YRC Public Data Repository - Protein Structure Prediction

Protein:	YLR290C
Organism:	Saccharomyces cerevisiae
Length:	277 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YLR290C.

Description	E-value	Query Range	Subject Range
gi\|4240415 - gi\|4240415\|gb\|AAD13546.1\| NDP-hexose 4,6-dehydratase homolog [Streptomyces cyanogenus]	8.0E-75	[3..272]	[2..242]
gi\|160285643, gi... - gi\|209870414\|pdb\|3BXX\|F Chain F, Binding Of Two Substrate Analogue Molecules To Dihydroflavonol 4-Re...	9.0E-75	[2..269]	[5..251]
gi\|10505382 - gi\|10505382\|gb\|AAG18457.1\|AF306787_1 AprE [Streptomyces tenebrarius]	3.0E-74	[3..272]	[1..245]
gi\|7437238 - pir\|\|H69105 dTDP-glucose 4,6-dehydratase - Methanobacterium thermoautotrophicum (strain Delta H) gi\|15679777, gi\|... - gi\|2622920\|gb\|AAB86255.1\| dTDP-glucose 4,6-dehydratase [Methanothermobacter thermautotrophicus str. ...	1.0E-73	[4..272]	[3..239]
gi\|3789898 - gi\|3789898\|gb\|AAC68681.1\| TDP-glucose-4,6-dehydratase [Streptomyces venezuelae]	2.0E-72	[3..272]	[1..243]
gi\|6002934 - gi\|6002934\|gb\|AAF00211.1\|AF164960_7 dNDP-glucose 4,6-dehydratase [Streptomyces fradiae]	2.0E-72	[3..272]	[1..241]
gi\|134102913, gi... - gi\|134102913\|ref\|YP_001108574.1\| dTDP-glucose 4,6-dehydratase [Saccharopolyspora erythraea NRRL 2338... gi\|567874 - gi\|567874\|gb\|AAA68211.1\| thymidine diphosphoglucose 4,6-dehydratase [Saccharopolyspora erythraea NRR...	2.0E-72	[3..272]	[1..243]
gi\|5579434 - gi\|5579434\|gb\|AAD45555.1\|U70376_20 SpcJ [Streptomyces netropsis]	9.0E-72	[3..272]	[1..243]
gi\|9055396 - gi\|9055396\|gb\|AAF82605.1\| dTDP-glucose 4,6-dehydratase [Streptomyces rimosus subsp. paromomycinus]	2.0E-71	[3..272]	[1..240]

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Predicted Domain #1

Region A:
Residues: [1-201]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIPKLIVFGG NGFLGKRICQ EAVTSGYQVV SVSRSGKAPH SNELNDKQWM QEVQWTAADI  60
   61 FKPDSYHELL NNATNVVHSL GILLENENYK QTLSKSPTYD SKSRLLSFGA GPNPLKKSSP 120
  121 YFTYEMMNKQ SAIILADTFK QKILKKSKKE QEKANQRSFT YISADKGFPL IPSGYINSKR 180
  181 EAEIELEKMQ RYFRPIIVRP G

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [250-277]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QQVSKSVLKN IENPDFKGVV TLEEILKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.69897
Match:	1lrkA_
Description:	Uridine diphosphogalactose-4-epimerase (UDP-galactose 4-epimerase)
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [202-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FMFDEHRNAI GPRSFIHTAL ELLYCGNKFL LRNKLQLLND LIRPTVST

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	71.69897
Match:	1lrkA_
Description:	Uridine diphosphogalactose-4-epimerase (UDP-galactose 4-epimerase)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits