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View Structure Prediction Details

Protein: YCS4
Organism: Saccharomyces cerevisiae
Length: 1176 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YCS4.

Description E-value Query
Range
Subject
Range
NCAPD2 - non-SMC condensin I complex, subunit D2
1510.0 [0..51] [1167..59]
gi|20072034, gi|... - gi|22165392|ref|NP_666283.1| non-SMC condensin I complex, subunit D2 [Mus musculus], gi|20072034|gb|...
1509.0 [0..50] [1175..58]
gi|114643042, gi... - gi|114643044|ref|XP_001161664.1| PREDICTED: chromosome condensation-related SMC-associated protein 1...
1506.0 [0..51] [1167..59]
gi|109095218 - gi|109095218|ref|XP_001105024.1| PREDICTED: chromosome condensation-related SMC-associated protein 1...
1479.0 [0..50] [1167..58]
gi|73997747 - gi|73997747|ref|XP_534910.2| PREDICTED: similar to Condensin subunit 1 (Chromosome condensation-rela...
1466.0 [0..50] [1167..70]

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Predicted Domain #1
Region A:
Residues: [1-129]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGFSLSEYL TKFQTTDRES YPRLQDPSRE LNVIIDQLAV SPEQIDASPD SLEALIDLCH  60
   61 DFPHLTPKLQ TQLSYLISSS LSNLSKDIKA NLSSNVNFTE IGGLIPQWKR HLEEYGYLIQ 120
  121 VLLTFLQDE

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 12.5
Match:
Description: No description for 1ejlI was found.

Predicted Domain #2
Region A:
Residues: [130-191]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LHKVSSQSTN LNRSAKNSKN DSANVELFKR DCNQMENLLE SITKLLEINL SKIFQTTPEK  60
   61 DL

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 12.5
Match:
Description: No description for 1ejlI was found.

Predicted Domain #3
Region A:
Residues: [192-253]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FIGLFTRPLF VLLEIEPVTK VSSLKMFIQR ILAMCVKNHG QSSSIQSSLM TNLTYFLHLS  60
   61 VF

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 12.5
Match:
Description: No description for 1ejlI was found.

Predicted Domain #4
Region A:
Residues: [254-399]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NAELLKLLND EYNYPQLTED ILKEISTRVF NAKDTTGPKA ISNFLIKLSE LSPGIMLRQM  60
   61 NLVITLLNNS SITLRCSVVE ACGNIVAELA QDPQTMEHYK QQIAVLIELL EERFQDSNPY 120
  121 VRTKAIQGCS KICDLSSKFN KSKAKF

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.05
Match:
Description: No description for 1jpwA was found.

Predicted Domain #5
Region A:
Residues: [400-526]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TSLAVRSLQD RSSLVRRNSV KLLSKLLLKH PFKAIHGSQL RLSEWEEYLK GSESQLNSTL  60
   61 KKVESQETLN DTIERSLIEE EVEQDEGQCR TELEGSFNKS AELSRIENEV ENINATNTSV 120
  121 LMKLKLM

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.05
Match:
Description: No description for 1jpwA was found.

Predicted Domain #6
Region A:
Residues: [527-649]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVYYKDAISF IKEIHKSIEL ISNLLFSKNR NEVLESMDFL VLADAFDIEL SEFGIKKMLH  60
   61 LVWMKGTNDE GTSISVHLIE CYKQLFLTAP DSCNMQEKAA HIAKNLINLS IGASIADLAS 120
  121 LEQ

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.05
Match:
Description: No description for 1jpwA was found.

Predicted Domain #7
Region A:
Residues: [650-703]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LLGMMYEQKL IDQHVINILW AIYNSASKAS MQKEQNVNNR DSEKGFSKEQ IHGS

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.05
Match:
Description: No description for 1jpwA was found.

Predicted Domain #8
Region A:
Residues: [704-887]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IIILGMLSLA DNEIALKGLE SLLNIGLGAV GLKDLTLCRY SCLALERMVP KRSTIITKAI  60
   61 NQELEDVAVK KLYAIIINYT KDNEYYPMCE QALSALFTIS SKPDILATDL IREKTMMTFG 120
  121 KPEEEDSILS LEQSSRVVSL SQLLFIVGQV AIKTLVYLEK CEAEFKKRKI EAETRNGKVK 180
  181 NQGA

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 14.05
Match:
Description: No description for 1jpwA was found.

Predicted Domain #9
Region A:
Residues: [888-945]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DVTNTTQDNG GDKELEMIGG TNEDDFTDAI QFVKENELLF GEKSILGKFC PIVEEIVS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.682 a.60.1 SAM/Pointed domain
View Download 0.682 a.60.1 SAM/Pointed domain
View Download 0.646 a.8.1 Bacterial immunoglobulin/albumin-binding domains
View Download 0.636 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.636 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.609 a.5.1 DNA helicase RuvA subunit, C-terminal domain
View Download 0.523 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.523 a.5.7 4-hydroxy-2-oxovalerate aldolase DmpG, communication domain
View Download 0.478 a.4.1 Homeodomain-like

Predicted Domain #10
Region A:
Residues: [946-1176]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NSSRFSDPML QRTATLCLEK LMCLSSKYCE KSLPLLITVM EKSPDPTIRS NAVLGLGDMA  60
   61 VCFNNLVDEN TDYLYRRLHD ENLMVQRTCL MTVTFLILAG QVKVKGQLGE MAKCLDNPDQ 120
  121 GISDMCRLFF TELASKDNAI YNGFIDIFSN LSSDDLLGKE SFKKIIKFLL TFIDKERHQK 180
  181 QLNEKLVGRL RKCETQKQWD DIAFVLNNLP YKNEDVTALL EQGFKVVSAK E

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.30103
Match: 1gw5B
Description: Adaptin beta subunit N-terminal fragment
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle