YRC Public Data Repository - Protein Structure Prediction

Protein:	CDC123
Organism:	Saccharomyces cerevisiae
Length:	360 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CDC123.

Description	E-value	Query Range	Subject Range
gi\|73949144 - gi\|73949144\|ref\|XP_535189.2\| PREDICTED: similar to D123 gene product [Canis familiaris]	539.0	[0..14]	[355..106]
CD123_MOUSE - Cell division cycle protein 123 homolog OS=Mus musculus GN=Cdc123 PE=1 SV=2	530.0	[0..14]	[355..1]
CD123_RAT - Cell division cycle protein 123 homolog OS=Rattus norvegicus GN=Cdc123 PE=1 SV=1	527.0	[0..14]	[355..1]
CD123_MACFA - Cell division cycle protein 123 homolog OS=Macaca fascicularis GN=CDC123 PE=2 SV=1 gi\|109088205 - gi\|109088205\|ref\|XP_001083055.1\| PREDICTED: similar to D123 gene product [Macaca mulatta]	523.0	[0..14]	[355..1]
gi\|114629341, gi... - gi\|114629343\|ref\|XP_001136850.1\| PREDICTED: hypothetical protein isoform 9 [Pan troglodytes], gi\|114...	522.0	[0..14]	[355..1]
CDC123 - cell division cycle 123 homolog (S. cerevisiae)	520.0	[0..14]	[355..1]
CD123_BOVIN - Cell division cycle protein 123 homolog OS=Bos taurus GN=CDC123 PE=2 SV=1	515.0	[0..14]	[355..1]

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Predicted Domain #1

Region A:
Residues: [1-174]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQEYTTFI DIPVTRAQVE HCSYSFWSSL YPKYVPKSIV LKSLPKKFIQ YLEQDGIKLP  60
   61 QEENSRSVYT EEIIRNEDND YSDWEDDEDT ATEFVQEVEP LIDFPELHQK LKDALNELGA 120
  121 VAPKLNWSAP RDATWILPNN TMKCNEVNEL YLLLNASNYI MHDLQRAFKG CVDG

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [175-360]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DDIKGLKFDL VLRQWCDMNP ALEFRVFVKN AHIVGATQRD LNYYDYLDEL SDTFKDLIDE  60
   61 IVHDVVLPKF PDKSFVLDVY IPRPFNKIFI VDINPFARKT DSLLFSWNEI AAIAPPKNDV 120
  121 EDYELRLVTR HNTGRFASKE HSENHVPQDL VEASLNPEAI RELTQKWKEL LSQQAKEESS 180
  181 DSENET

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits