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View Structure Prediction Details

Protein: ENT2
Organism: Saccharomyces cerevisiae
Length: 613 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ENT2.

Description E-value Query
Range
Subject
Range
gi|119592811, gi... - gi|194248095|ref|NP_001123544.1| epsin 1 isoform b [Homo sapiens], gi|119592814|gb|EAW72408.1| epsin...
6.0E-71 [7..267] [8..269]
EPN1_RAT - Epsin-1 OS=Rattus norvegicus GN=Epn1 PE=1 SV=1
5.0E-70 [7..270] [8..272]
gi|147906994, gi... - gi|2072301|gb|AAC60123.1| mitotic phosphoprotein 90 [Xenopus laevis], gi|147906994|ref|NP_001081892....
4.0E-62 [9..270] [1..268]
lqf-PB, lqf-PD - The gene liquid facets is referred to in FlyBase by the symbol Dmel\lqf (CG8532, FBgn0028582). It is...
9.0E-61 [7..264] [10..259]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-60 [7..257] [139..374]
EPN3_MOUSE - Epsin-3 OS=Mus musculus GN=Epn3 PE=1 SV=1
3.0E-56 [7..235] [8..258]

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Predicted Domain #1
Region A:
Residues: [1-159]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKQFVRSAK NMMKGYSSTQ VLVRDATAND SRTPSIDTLD DLAQRSYDSV DFFEIMDMLD  60
   61 KRLNDKGKYW RHVAKSLTVL DYLVRFGSEN CVLWCRENFY VIKTLREFRH ENESGFDEGQ 120
  121 IIRVKAKELV SLLNDEERLR EERSMNTRNR RANRAARPR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 330.54902
Match: 1inzA_
Description: Epsin 1
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.229007340928547 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [160-521]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRRQRTRSNP HDSSPSYQDD LEKALEESRI TAQEDEQRRR ELAQYDDEDP DFQAALQLSK  60
   61 EEEELKQLQE LQRLQKQQQS LSQFQAPLQQ QQPQQQPAYY DIFGNPISQD EYLQYQYQQD 120
  121 QEQAMAQQRW LDQQQEQQQL AEQQYFQQQQ QAAAAASALQ QQQTAANMQQ QQQQPADFQQ 180
  181 PLPTGSNNPF SMDNLERQKQ EQQHAQLQRQ QEEARQQQEQ LKLQQLQRQQ QEEAQLHQKR 240
  241 QEEAQLQQQQ AQLLQQQAQF QQQQPLKQTR TGNQSISDKY SDLNTLLATG TGIDTFGNTG 300
  301 EARIPAQHTK TGTFINSQGT GYKQVTNEPK NNPFLSNQYT GLPSTNIVPT QTGYGFGNQP 360
  361 QS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [522-613]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PPTNSPQQNP TGISYSQPQQ QQQPQQQPQY MQNFQQQQPQ YAQNFQQQPQ YTQNYQQQPQ  60
   61 YIQPHQQQQQ QQQQQQQQQG YTPDQGVSLI DL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.431 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.546 d.120.1 Cytochrome b5
View Download 0.309 a.118.14 FliG
View Download 0.360 a.7.6 Ribosomal protein S20
View Download 0.281 a.4.5 "Winged helix" DNA-binding domain
View Download 0.275 a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.272 a.46.1 Methionine synthase domain
View Download 0.270 a.60.9 lambda integrase-like, N-terminal domain
View Download 0.269 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.240 c.23.1 CheY-like
View Download 0.226 a.29.4 RecG, N-terminal domain
View Download 0.225 a.7.6 Ribosomal protein S20
View Download 0.222 d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.221 a.163.1 Crustacean CHH/MIH/GIH neurohormone
View Download 0.214 d.15.3 MoaD/ThiS
View Download 0.209 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.207 a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.205 a.156.1 S13-like H2TH domain
View Download 0.205 d.15.2 CAD & PB1 domains
View Download 0.203 a.7.1 Spectrin repeat


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle