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View Structure Prediction Details

Protein: ATG26
Organism: Saccharomyces cerevisiae
Length: 1198 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATG26.

Description E-value Query
Range
Subject
Range
ATG26 - UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside m...
ATG26_YEAST - Sterol 3-beta-glucosyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ATG26 ...
0.0 [1..1198] [1..1198]
jgi|Picpa1|39633... - null
ATG26_PICPA - Sterol 3-beta-glucosyltransferase OS=Pichia pastoris GN=ATG26 PE=3 SV=1
ATG26_PICPG - Sterol 3-beta-glucosyltransferase OS=Komagataella pastoris (strain GS115 / ATCC 20864) GN=ATG26 PE=3...
0.0 [58..1181] [31..1200]
gi|4768599 - gi|4768599|gb|AAD29571.1|AF091398_1 UDP-glucose:sterol glucosyltransferase [Candida albicans]
0.0 [62..1188] [170..1466]
UGT1A10 - UDP glucuronosyltransferase 1 family, polypeptide A10
0.0 [714..1185] [2..483]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [714..1185] [2..483]
gi|6537142 - gi|6537142|gb|AAF15548.1|AF104338_1 UDP-glucuronosyltransferase UGT1A08 [Macaca fascicularis]
0.0 [714..1185] [2..483]
gi|18308170, gi|... - gi|28461127|ref|NP_787040.1| UDP glycosyltransferase 1 family, polypeptide A8 [Rattus norvegicus], g...
0.0 [720..1185] [6..483]

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Predicted Domain #1
Region A:
Residues: [1-161]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPITQIISAS DSEAGPKPSI SLVPDKPSEP ETSPRHHRLS RSLSKFKRWR GRSNSSLSMG  60
   61 SSEQQELQDS PNEARSDDDE NGYNNDNADD LAKSKYMMKS IAGLLTTASV YAGMNNAQEM 120
  121 NVLSQVDSEE SDSSDSFQEN IGRNEVKSKK ENLKTKSHPE V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [162-374]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PRLDKRKPTL FDFSITREKL SKDNVAKLRQ RFCLDEQEPF LNDFPAWLLK DVLVQGHIFI  60
   61 TTKHFLFFAY LPKNPRSVKM SGNLNIRTKL IRSTRYWCVL KNHLFSMYTS STELYFPVLT 120
  121 IDLREVQKIE TQKHTLNGSA TKTFKLYTDE STFKFNADSE FSAKSWVNAL KKEQFAAQNS 180
  181 ENNSISLKIP LPNIIEIDDQ PIVNKALTLR LRA

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 13.65
Match: 1eazA
Description: Tapp1
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [375-443]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LESSQTYAID DFMFVFMDGS GSQVKESLGE QLAILQKSGV NTLYYDIPAK KSKSSFGKET  60
   61 PATVEQKNN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [444-712]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEDSKYLNVP TSAVPSSENG KKSRFRFRER SNSWFRRAKP LEDSQVEDVE EIYKDAANDI  60
   61 DSSVHSTIHI HEQEDSQEQT VAWKPSHLKN FAEMWAAKPI HYRNKFIPFQ KDDTYLIKET 120
  121 EEVSANERFR YHFKFNKEKS LISTYYTYLN RNVPVYGKIY VSNDTVCFRS LLPGSNTYMV 180
  181 LPLVDVETCY KEKGFRFGYF VLVIVIHGHE ELFFEFSTEV ARDDIERILL KLLDNIYASS 240
  241 AEGSNISSAS LGDVQHNPDS AKLKLFEDK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [713-866]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INAEGFEVPL MIDENPHYKT SIKPNKSYKF GLLTIGSRGD VQPYIALGKG LIKEGHQVVI  60
   61 ITHSEFRDFV ESHGIQFEEI AGNPVELMSL MVENESMNVK MLREASSKFR GWIDALLQTS 120
  121 WEVCNRRKFD ILIESPSAMV GIHITEALQI PYFR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [1148-1198]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKTAISAIYN ELEYARSVTL SRVKTPRKKE ENVDATKLTP AETTDEGWTM I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 192.758605
Match: 1iirA_
Description: UDP-glucosyltransferase GtfB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring hexosyl groups 3.55635413938621 bayes_pls_golite062009
catalytic activity 2.65148466065976 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 2.62403914335522 bayes_pls_golite062009
glycogen phosphorylase activity 2.3376682145987 bayes_pls_golite062009
glucosyltransferase activity 2.11024512158394 bayes_pls_golite062009
UDP-glycosyltransferase activity 1.93518808027897 bayes_pls_golite062009
UDP-glucosyltransferase activity 1.84595685206241 bayes_pls_golite062009
UDP-N-acetylglucosamine 2-epimerase activity 1.55280519670033 bayes_pls_golite062009
transferase activity 1.47703555225615 bayes_pls_golite062009
alpha,alpha-trehalose-phosphate synthase (UDP-forming) activity 0.665466604531839 bayes_pls_golite062009
binding 0.634126409568608 bayes_pls_golite062009
phosphorylase activity 0.296436712681472 bayes_pls_golite062009
protein binding 0.198267161626932 bayes_pls_golite062009

Predicted Domain #6
Region A:
Residues: [867-974]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFTMPWTRTR AYPHAFIVPD QKRGGNYNYL THVLFENVFW KGISGQVNKW RVETLGLGKT  60
   61 NLFLLQQNNV PFLYNVSPTI FPPSIDFSEW VRVTGYWFLD DKSTFKPP

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [1143-1147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKEDG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 192.758605
Match: 1iirA_
Description: UDP-glucosyltransferase GtfB
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [975-1142]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AELQEFISEA RSKGKKLVYI GFGSIVVSNA KEMTEALVEA VMEADVYCIL NKGWSERLGD  60
   61 KAAKKTEVDL PRNILNIGNV PHDWLFPQVD AAVHHGGSGT TGASLRAGLP TVIKPFFGDQ 120
  121 FFYAGRVEDI GVGIALKKLN AQTLADALKV ATTNKIMKDR AGLIKKKI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 192.758605
Match: 1iirA_
Description: UDP-glucosyltransferase GtfB
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle