YRC Public Data Repository - Protein Structure Prediction

Protein:	TOS4
Organism:	Saccharomyces cerevisiae
Length:	489 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TOS4.

Description	E-value	Query Range	Subject Range
PLM2 - Forkhead Associated domain containing protein and putative transcription factor found associated wit... PLM2_YEAST - Protein PLM2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=PLM2 PE=1 SV=1	672.0	[0..18]	[489..6]
gi\|49641411 - gi\|49641411\|emb\|CAH01129.1\| KLLA0C01848p [Kluyveromyces lactis] gi\|49641411, gi\|... - gi\|50304645\|ref\|XP_452278.1\| unnamed protein product [Kluyveromyces lactis], gi\|49641411\|emb\|CAH0112...	345.0	[0..1]	[489..1]
gi\|44985348 - gi\|44985348\|gb\|AAS54061.1\| AFR689Wp [Ashbya gossypii ATCC 10895] gi\|44985348, gi\|... - gi\|45199208\|ref\|NP_986237.1\| AFR689Wp [Ashbya gossypii ATCC 10895], gi\|44985348\|gb\|AAS54061.1\| AFR68...	326.0	[0..18]	[489..26]
YK42_SCHPO - Transcription factor P14E8.02 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAP14E8.02 ... SPAP14E8.02 - transcription factor	318.0	[0..236]	[487..302]
gi\|50285185, gi\|... - gi\|50285185\|ref\|XP_445021.1\| unnamed protein product [Candida glabrata], gi\|49524324\|emb\|CAG57921.1\|... gi\|27948798, gi\|... - gi\|49524324\|emb\|CAG57921.1\| unnamed protein product [Candida glabrata], gi\|27948798\|gb\|AAO25588.1\| T...	286.0	[0..1]	[489..1]
gi\|27948810 - gi\|27948810\|gb\|AAO25598.1\| TOS4 [Kluyveromyces delphensis]	275.0	[0..18]	[489..4]
gi\|50422673, gi\|... - gi\|50422673\|ref\|XP_459913.1\| hypothetical protein DEHA0E14531g [Debaryomyces hansenii CBS767], gi\|49...	189.0	[0..18]	[488..8]
orf19.668, orf19... - orf19.668 CGDID:CAL0001066 Assembly 19, Contig19-10064 (31727, 33205) CDS, translated using codon ta... gi\|46435357, gi\|... - gi\|68484540\|ref\|XP_713801.1\| hypothetical protein CaO19.668 [Candida albicans SC5314], gi\|68484461\|r...	188.0	[0..1]	[488..4]
gi\|49649284 - gi\|49649284\|emb\|CAG78994.1\| YALI0E01430p [Yarrowia lipolytica] gi\|50551881, gi\|... - gi\|50551881\|ref\|XP_503415.1\| YALI0E01430p [Yarrowia lipolytica], gi\|49649284\|emb\|CAG78994.1\| unnamed...	150.0	[0..242]	[488..511]
gi\|116195016, gi... - gi\|88180019\|gb\|EAQ87487.1\| hypothetical protein CHGG_04106 [Chaetomium globosum CBS 148.51], gi\|1161...	123.0	[0..293]	[487..324]

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Predicted Domain #1

Region A:
Residues: [1-183]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSQFPSSPY RTVDPYSPPN YKQQPNCPSS NYEKAGKTAS ESIGNFGKGD YPTPFPSSSI  60
   61 GRVSSPVRSN KVDAIPSSPA FPGQLAETSP KFSSKLSSPS RHTRVINAEL DPSKISTITV 120
  121 GRNSSQCDVA LCKNKFISRV HASITYLPQT NEVKIHCFSM NGLIVTYRKQ FDCYQLKDTM 180
  181 NNN

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	7.02
Match:
Description:	No description for 1g3gA was found.

Predicted Domain #2

Region A:
Residues: [184-266]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NRAYRLVPRF SNEKCVKEIQ DEGGFINFTL EEGDTVYMTY YKGIMLDFRQ VLLRISLKEK  60
   61 NSSSEPLRFE KKAEFESESE TKH

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.616	d.304.1	Description not found.
View	Download	0.613	d.317.1	Description not found.
View	Download	0.564	d.52.8	Description not found.
View	Download	0.544	d.109.1	Actin depolymerizing proteins
View	Download	0.544	d.109.1	Actin depolymerizing proteins
View	Download	0.532	d.58.4	Dimeric alpha+beta barrel
View	Download	0.529	d.50.3	PI-Pfui intein middle domain
View	Download	0.495	c.55.7	Methylated DNA-protein cysteine methyltransferase domain
View	Download	0.480	d.54.1	Enolase N-terminal domain-like

Predicted Domain #3

Region A:
Residues: [267-489]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSIRKHPLI FTDTSMDRPK KILKDSNKIS IGSDSGVAER MLNHFLNSKS SPLSSVSSVD  60
   61 HEEQTLRQDS LSSDKNPMTM KKPKLNKRVL PSKPKKSVKE NLDELSRRNI DVMHLQHILT 120
  121 NHLAFANVQQ TPLFQLQQVN SQISELSRDE LRSILSDAKC VGVIYRHGKD AAGKPLDEEY 180
  181 FYDLENDDDY ERRNLVSSLK GGRTGLRSCR RTHKQYFWKK PAK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits