YRC Public Data Repository - Protein Structure Prediction

Protein:	ZRT2
Organism:	Saccharomyces cerevisiae
Length:	422 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ZRT2.

Description	E-value	Query Range	Subject Range
ZRT2_YEAST - Zinc-regulated transporter 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ZRT2 PE=1 S... gi\|190406159 - gi\|190406159\|gb\|EDV09426.1\| zinc-regulated transporter 2 [Saccharomyces cerevisiae RM11-1a] ZRT2 - Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc condit...	3.0E-85	[1..422]	[1..422]
gi\|6331192 - gi\|6331192\|dbj\|BAA86579.1\| KIAA1265 protein [Homo sapiens]	2.0E-67	[21..421]	[408..825]
IRT3_ARATH - Fe(2+) transport protein 3, chloroplastic OS=Arabidopsis thaliana GN=IRT3 PE=2 SV=3	2.0E-64	[9..422]	[46..425]
gi\|14582255 - gi\|14582255\|gb\|AAK69429.1\|AF275751_1 ZIP-like zinc transporter [Thlaspi caerulescens]	2.0E-63	[9..422]	[40..408]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	6.0E-63	[3..418]	[296..736]

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Predicted Domain #1

Region A:
Residues: [1-205]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDLIARDDS VDTCQASNGY NGHAGLRILA VFIILISSGL GVYFPILSSR YSFIRLPNWC  60
   61 FFIAKFFGSG VIVATAFVHL LQPAAEALGD ECLGGTFAEY PWAFGICLMS LFLLFFTEII 120
  121 THYFVAKTLG HDHGDHGEVT SIDVDAPSSG FVIRNMDSDP VSFNNEAAYS IHNDKTPYTT 180
  181 RNEEIVATPI KEKEPGSNVT NYDLE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [206-422]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PGKTESLANE LVPTSSHATN LASVPGKDHY SHENDHQDVS QLATRIEEED KEQYLNQILA  60
   61 VFILEFGIIF HSVFVGLSLS VAGEEFETLF IVLTFHQMFE GLGLGTRVAE TNWPESKKYM 120
  121 PWLMGLAFTL TSPIAVAVGI GVRHSWIPGS RRALIANGVF DSISSGILIY TGLVELMAHE 180
  181 FLYSNQFKGP DGLKKMLSAY LIMCCGAALM ALLGKWA

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	57.167491
Match:	PF02535
Description:	ZIP Zinc transporter

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [245-422]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SQLATRIEEE DKEQYLNQIL AVFILEFGII FHSVFVGLSL SVAGEEFETL FIVLTFHQMF  60
   61 EGLGLGTRVA ETNWPESKKY MPWLMGLAFT LTSPIAVAVG IGVRHSWIPG SRRALIANGV 120
  121 FDSISSGILI YTGLVELMAH EFLYSNQFKG PDGLKKMLSA YLIMCCGAAL MALLGKWA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits