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View Structure Prediction Details

Protein: HRT3
Organism: Saccharomyces cerevisiae
Length: 344 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HRT3.

Description E-value Query
Range
Subject
Range
HRT3_YEAST - F-box protein HRT3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HRT3 PE=1 SV=1
HRT3 - Putative SCF-ubiquitin ligase F-box protein, based on both genetic and physical interactions and seq...
0.0 [1..344] [1..344]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
0.0 [7..340] [185..539]
FBXO9 - F-box protein 9
0.0 [7..340] [85..439]
gi|125628673, gi... - gi|18044861|gb|AAH20074.1| F-box protein 9 [Mus musculus], gi|125628673|ref|NP_076094.2| f-box only ...
0.0 [7..340] [74..428]
SKI32_ARATH - F-box protein 7 OS=Arabidopsis thaliana GN=SKIP32 PE=1 SV=1
4.0E-48 [87..252] [46..194]

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Predicted Domain #1
Region A:
Residues: [1-73]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVDYEKDPR AKEAIAIWEK GVLKEKDGSM SDAINFYRSA LKIHDNVESL YRKKILDEWM  60
   61 LHKKLSGLSM TTD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.905 0.987 nuclear ubiquitin ligase complex a.4.5 "Winged helix" DNA-binding domain

Predicted Domain #2
Region A:
Residues: [74-189]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APDEQNETGK DDLSVEENAE LQPCWILEIL PDDILLRIIK KVILMSGESW VNLSMTCSTF  60
   61 SKLCFHDSVP FKTFAKYIYS KQIYDKMAMD LNGITDINTF EKEIWRGDDY RMLRER

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 2.481486
Match: PF00646
Description: F-box domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [190-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PYIKFEGVYI SVVNYVRYGS NAESSLSLLK PVHMITYYRY FRFYENGQCL RLLSTDEPSA  60
   61 VVKHFSKENK PRHSHMCYWS LGFDYDFGHL KITRSDEKYT FIEEFQIKNQ GNKRYQRLKW 120
  121 LSSIVVDKEG NASNCSLRNE KSFFFSRVKS FKDPG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle