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View Structure Prediction Details

Protein: EMP46
Organism: Saccharomyces cerevisiae
Length: 444 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EMP46.

Description E-value Query
Range		 Subject
Range
EMP46 - Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function i...
EMP46_YEAST - Protein EMP46 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EMP46 PE=1 SV=1
 0.0 [1..444] [1..444]
LMAN1 - lectin, mannose-binding, 1
 0.0 [21..414] [2..418]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 0.0 [21..414] [2..418]
LMAN1_CHLAE - Protein ERGIC-53 OS=Chlorocebus aethiops GN=LMAN1 PE=2 SV=1
 0.0 [21..414] [2..418]
LMAN1_MOUSE - Protein ERGIC-53 OS=Mus musculus GN=Lman1 PE=1 SV=1
 0.0 [46..397] [42..413]
LMAN1_RAT - Protein ERGIC-53 OS=Rattus norvegicus GN=Lman1 PE=1 SV=1
 0.0 [46..398] [42..414]
ergic53-PA, ergi... - The gene ergic53 is referred to in FlyBase by the symbol Dmel\ergic53 (CG6822, FBgn0035909). It is a...
gi|220956014 - gi|220956014|gb|ACL90550.1| ergic53-PA [synthetic construct]
 1.0E-96 [55..368] [34..352]

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Predicted Domain #1
Region A:
Residues: [1-277] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTTRKTASSL QLLGKITGTK AGTKQKKMNF INGLIWLYMC VWMVHGKVTQ KDELKWNKGY  60
   61 SLPNLLEVTD QQKELSQWTL GDKVKLEEGR FVLTPGKNTK GSLWLKPEYS IKDAMTIEWT 120
  121 FRSFGFRGST KGGLAFWLKQ GNEGDSTELF GGSSKKFNGL MILLRLDDKL GESVTAYLND 180
  181 GTKDLDIESS PYFASCLFQY QDSMVPSTLR LTYNPLDNHL LKLQMDNRVC FQTRKVKFMG 240
  241 SSPFRIGTSA INDASKESFE ILKMKLYDGV IEDSLIP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.522879
Match: 1gv9A_
Description: Carbohydrate-recognition domain of P58/ERGIC-53
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [278-444] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NVNPMGQPRV VTKVINSQTG EESFREKMPF SDKEESITSN ELFEKMNKLE GKIMANDIDP  60
   61 LLRKMNKIVE NERELIQRLR PLLDLKKTAI SDDSFQDFLS MNANLDRLIK EQEKIRQDAK 120
  121 LYGKQTKGHD EIFSKISVWL ALLIFIMITL AYYMFRINQD IKKVKLL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 2.69897
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle