YRC Public Data Repository - Protein Structure Prediction

Protein:	PDC1
Organism:	Saccharomyces cerevisiae
Length:	563 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PDC1.

Description	E-value	Query Range	Subject Range
gi\|17232105, gi\|... - gi\|17232105\|ref\|NP_488653.1\| acetolactate synthase 3 catalytic subunit [Nostoc sp. PCC 7120], gi\|171... gi\|25291313 - pir\|\|AE2382 acetohydroxy acid synthase [imported] - Nostoc sp. (strain PCC 7120)	0.0	[3..558]	[32..593]
gi\|7436698 - pir\|\|C70341 acetolactate synthase (EC 4.1.3.18) large chain - Aquifex aeolicus gi\|15605942, gi\|... - gi\|2983101\|gb\|AAC06706.1\| acetolactate synthase large subunit [Aquifex aeolicus VF5], gi\|15605942\|re...	0.0	[1..555]	[1..563]
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	0.0	[3..558]	[11..572]
Q66EL8\|Q66EL8_YERPS - Acetolactate synthase III, valine sensitive, large subunit FAD and thiamine PPi binding - Yersinia p... gi\|77631655, gi\|... - gi\|77631655\|ref\|ZP_00794241.1\| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate synth... gi\|161511301 - gi\|161511301\|ref\|NP_994917.2\| acetolactate synthase 3 catalytic subunit [Yersinia pestis biovar Micr... gi\|161484748 - gi\|161484748\|ref\|NP_670937.2\| acetolactate synthase 3 catalytic subunit [Yersinia pestis KIM] gi\|186894031, gi... - gi\|186894031\|ref\|YP_001871143.1\| acetolactate synthase 3 catalytic subunit [Yersinia pseudotuberculo... gi\|169752280, gi... - gi\|170025746\|ref\|YP_001722251.1\| acetolactate synthase 3 catalytic subunit [Yersinia pseudotuberculo... gi\|229837069, gi... - gi\|229837069\|ref\|ZP_04457234.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis Pes... gi\|150260425, gi... - gi\|150260425\|ref\|ZP_01917153.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis CA8... gi\|229696794, gi... - gi\|229840428\|ref\|ZP_04460587.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis bio... gi\|229843030, gi... - gi\|229843030\|ref\|ZP_04463180.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis bio... gi\|89104759 - gi\|89104759\|ref\|ZP_01177293.1\| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate synth... gi\|108809551, gi... - gi\|108809551\|ref\|YP_653467.1\| acetolactate synthase 3 catalytic subunit [Yersinia pestis Antiqua], g... gi\|77633509 - gi\|77633509\|ref\|ZP_00795637.1\| COG0028: Thiamine pyrophosphate-requiring enzymes [acetolactate synth... gi\|229682102, gi... - gi\|229900763\|ref\|ZP_04515887.1\| acetolactate synthase isozyme III large subunit [Yersinia pestis Nep... gi\|25291303 - pir\|\|AI0066 acetolactate synthase (EC 4.1.3.18) isozyme III large chain [imported] - Yersinia pestis... gi\|218927736, gi... - gi\|218927736\|ref\|YP_002345611.1\| acetolactate synthase 3 catalytic subunit [Yersinia pestis CO92], g... gi\|51588307, gi\|... - gi\|51595025\|ref\|YP_069216.1\| acetolactate synthase 3 catalytic subunit [Yersinia pseudotuberculosis ...	0.0	[1..553]	[1..561]
gi\|152905 - gi\|152905\|gb\|AAA26594.1\| acetohydroxy acid synthase (AHAS) gi\|152905 - gi\|152905\|gb\|AAA26594.1\| acetohydroxy acid synthase (AHAS) [Arthrospira platensis]	0.0	[2..558]	[10..572]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[2..558]	[10..572]
gi\|6478282 - gi\|6478282\|gb\|AAF13791.1\|AF129502_2 acetohydroxy acid synthase large subunit [Buchnera aphidicola] ILVI_BUCSC - Acetolactate synthase large subunit OS=Buchnera aphidicola subsp. Schlechtendalia chinensis GN=ilvI ...	0.0	[1..549]	[1..556]
ILVI_BUCAP - Acetolactate synthase large subunit OS=Buchnera aphidicola subsp. Schizaphis graminum GN=ilvI PE=3 S... ILVI_BUCAP - Acetolactate synthase large subunit OS=Buchnera aphidicola subsp. Schizaphis graminum (strain Sg) GN... gi\|3435164 - gi\|3435164\|gb\|AAC32333.1\| acetohydroxy acid synthase large subunit [Buchnera aphidicola]	0.0	[1..553]	[1..557]

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Predicted Domain #1

Region A:
Residues: [1-188]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEITLGKYL FERLKQVNVN TVFGLPGDFN LSLLDKIYEV EGMRWAGNAN ELNAAYAADG  60
   61 YARIKGMSCI ITTFGVGELS ALNGIAGSYA EHVGVLHVVG VPSISAQAKQ LLLHHTLGNG 120
  121 DFTVFHRMSA NISETTAMIT DIATAPAEID RCIRTTYVTQ RPVYLGLPAN LVDLNVPAKL 180
  181 LQTPIDMS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10166.0
Match:	1qpbA_
Description:	Pyruvate decarboxylase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [189-353]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKPNDAESEK EVIDTILALV KDAKNPVILA DACCSRHDVK AETKKLIDLT QFPAFVTPMG  60
   61 KGSIDEQHPR YGGVYVGTLS KPEVKEAVES ADLILSVGAL LSDFNTGSFS YSYKTKNIVE 120
  121 FHSDHMKIRN ATFPGVQMKF VLQKLLTTIA DAAKGYKPVA VPART

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10166.0
Match:	1qpbA_
Description:	Pyruvate decarboxylase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [354-563]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PANAAVPAST PLKQEWMWNQ LGNFLQEGDV VIAETGTSAF GINQTTFPNN TYGISQVLWG  60
   61 SIGFTTGATL GAAFAAEEID PKKRVILFIG DGSLQLTVQE ISTMIRWGLK PYLFVLNNDG 120
  121 YTIEKLIHGP KAQYNEIQGW DHLSLLPTFG AKDYETHRVA TTGEWDKLTQ DKSFNDNSKI 180
  181 RMIEIMLPVF DAPQNLVEQA KLTAATNAKQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10166.0
Match:	1qpbA_
Description:	Pyruvate decarboxylase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits