YRC Public Data Repository - Protein Structure Prediction

Protein:	AAT2
Organism:	Saccharomyces cerevisiae
Length:	432 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AAT2.

Description	E-value	Query Range	Subject Range
gi\|447739 - gi\|447739\|prf\|\|1915304A nylB upstream ORF	0.0	[17..424]	[1..401]
AATM_MOUSE - Aspartate aminotransferase, mitochondrial OS=Mus musculus GN=Got2 PE=1 SV=1	0.0	[8..424]	[21..430]
gi\|123981960, gi... - gi\|123996785\|gb\|ABM85994.1\| glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotrans... gi\|12653507 - gi\|12653507\|gb\|AAH00525.1\| Glutamic-oxaloacetic transaminase 2, mitochondrial (aspartate aminotransf...	0.0	[8..424]	[21..430]
AATM_HORSE - Aspartate aminotransferase, mitochondrial OS=Equus caballus GN=GOT2 PE=1 SV=1	0.0	[17..424]	[1..401]
AATM_RAT - Aspartate aminotransferase, mitochondrial OS=Rattus norvegicus GN=Got2 PE=1 SV=2	0.0	[8..424]	[21..430]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[8..424]	[21..433]
gi\|625212 - pir\|\|XNPGDM aspartate transaminase (EC 2.6.1.1) precursor, mitochondrial - pig AATM_PIG - Aspartate aminotransferase, mitochondrial OS=Sus scrofa GN=GOT2 PE=1 SV=2	0.0	[8..424]	[21..430]
AATM_BOVIN - Aspartate aminotransferase, mitochondrial OS=Bos taurus GN=GOT2 PE=1 SV=2	0.0	[8..424]	[21..430]

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Predicted Domain #1

Region A:
Residues: [1-61]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNKRTQEYKN TRAIMSATLF NNIELLPPDA LFGIKQRYGQ DQRATKVDLG IGAYRDDNGK  60
   61 P

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [342-432]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SSRITKMRHA LRDHLVKLGT PGNWDHIVNQ CGMFSFTGLT PQMVKRLEET HAVYLVASGR  60
   61 ASIAGLNQGN VEYVAKAIDE VVRFYTIEAK L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10111.0
Match:	1yaaA_
Description:	Aspartate aminotransferase, AAT
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [62-341]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WVLPSVKAAE KLIHNDSSYN HEYLGITGLP SLTSNAAKII FGTQSDAFQE DRVISVQSLS  60
   61 GTGALHISAK FFSKFFPDKL VYLSKPTWAN HMAIFENQGL KTATYPYWAN ETKSLDLNGF 120
  121 LNAIQKAPEG SIFVLHSCAH NPTGLDPTSE QWVQIVDAIA SKNHIALFDT AYQGFATGDL 180
  181 DKDAYAVRLG VEKLSTVSPV FVCQSFAKNA GMYGERVGCF HLALTKQAQN KTIKPAVTSQ 240
  241 LAKIIRSEVS NPPAYGAKIV AKLLETPELT EQWHKDMVTM

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	10111.0
Match:	1yaaA_
Description:	Aspartate aminotransferase, AAT
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits