YRC Public Data Repository - Protein Structure Prediction

Protein:	AYT1
Organism:	Saccharomyces cerevisiae
Length:	474 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AYT1.

Description	E-value	Query Range	Subject Range
gi\|190405992 - gi\|190405992\|gb\|EDV09259.1\| trichothecene 3-O-acetyltransferase [Saccharomyces cerevisiae RM11-1a] AYT1 - Acetyltransferase; catalyzes trichothecene 3-O-acetylation, suggesting a possible role in trichothec... AYT1_YEAST - Trichothecene 3-O-acetyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AYT1...	0.0	[1..474]	[1..474]
gi\|21436437, gi\|... - gi\|21536885\|gb\|AAM61217.1\| anthranilate N-hydroxycinnamoyl/benzoyltransferase-like protein [Arabidop...	2.0E-96	[1..473]	[1..448]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	2.0E-93	[2..463]	[11..437]
gi\|3724330 - gi\|3724330\|dbj\|BAA33771.1\| trichothecene 3-O-acetyltransferase [Fusarium sporotrichioides]	6.0E-93	[15..474]	[8..459]
gi\|18652312 - gi\|18652312\|gb\|AAL77060.1\|AF468022_1 putative acyltransferase [Cucumis melo]	3.0E-92	[2..465]	[11..438]

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Predicted Domain #1

Region A:
Residues: [1-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFRVKIISQK RTKSVQMLEN DQLDILGQQP SLYKLYTQIC SIYRVPDPSA HDHIVNTLTR  60
   61 GLETLAKNFQ WLAGNVVNEG ADEGNTGTYR IVPSDKIPLI VQDLREDLSA PTMDSLEKAD 120
  121 FPIYMLDEKT FAPCMTINPP GNTIGMAAKS GPVFAVQANF ISGGLVLTIV GQHNIMDITG 180
  181 QESIINLLNK SCHQKPFSDE ELLIGNIDKS KSIPLFDETW EPDTTLVHE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [314-329]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDVRKRLGLP ETYPGL

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [403-429]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WAKVSLYDVD FNLGLGKPKS VRRPRFI

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	9.77
Match:	1l5aA
Description:	VibH
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [230-313]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IVETSRNTSG EEKEQSCSSN STWAYVEFSA ISLQNLRILA MQTCTSGTKF VSTDDIVTAF  60
   61 IWKSVSRARL SRLKPETKSN LGRA

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [330-402]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LVNMTFNTGS LKSLDHKSLG VLASQIRRKL DPKVFDLAYN TCALATLLSR CPDKTKVSIP  60
   61 QPIDTLSGIM VSS

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [430-474]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SLESLIYFMP RSSRGEMVVA LCLRDKDWEC LNADKEWTNY ATHIG

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	9.77
Match:	1l5aA
Description:	VibH
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits