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View Structure Prediction Details

Protein: VPS13
Organism: Saccharomyces cerevisiae
Length: 3144 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

No multiple sequence alignment data found for VPS13.

Predicted Domain #1
Region A:
Residues: [1-394]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLESLAANLL NRLLGSYVEN FDPNQLNVGI WSGDVKLKNL KLRKDCLDSL NLPIDVKSGI  60
   61 LGDLVLTVPW SSLKNKPVKI IIEDCYLLCS PRSEDHENDE EMIKRAFRLK MRKVSEWELT 120
  121 NQARILSTQS ENKTSSSSSE KNNAGFMQSL TTKIIDNLQV TIKNIHLRYE DMDGIFTTGP 180
  181 SSVGLTLNEL SAVSTDSNWA PSFIDITQNI THKLLTLNSL CLYWNTDSPP LISDDDQDRS 240
  241 LENFVRGFKD MIASKNSTAP KHQYILKPVS GLGKLSINKL GSTEEQPHID LQMFYDEFGL 300
  301 ELDDTEYNDI LHVLSSIQLR QITKKFKKAR PSFAVSENPT EWFKYIAACV INEIHEKNKM 360
  361 WTWESMKEKC EQRRLYTKLW VEKLKLKNLE APLR

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [395-473]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPIQEAQLSE LHKDLTYDEI ILFRSVAKRQ YAQYKLGMTE DSPTPTASSN IEPQTSNKSA  60
   61 TKNNGSWLSS WWNGKPTEE

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [474-863]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDEDLIMTEE QRQELYDAIE FDENEDKGPV LQVPRERVEL RVTSLLKKGS FTIRKKKQNL  60
   61 NLGSIIFENC KVDFAQRPDS FLSSFQLNKF SLEDGSPNAL YKHIISVRNS SKDQSSIDNH 120
  121 ATGEEEEEDE PLLRASFELN PLDGLADSNL NIKLLGMTVF YHVHFITEVH KFFKASNQHM 180
  181 ETIGNIVNAA EATVEGWTTQ TRMGIESLLE DHKTVNVSLD LQAPLIILPL DPHDWDTPCA 240
  241 IIDAGHMSIL SDLVPKEKIK EIKELSPEEY DKIDGNEINR LMFDRFQILS QDTQIFVGPD 300
  301 IQSTIGKINT ASSTNDFRIL DKMKLELTVD LSILPKAYKL PTIRVFGHLP RLSLSINDIQ 360
  361 YKTIMNLIAN SIPSMIDDEE NNGDYVNYSS 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [864-1227]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GSEKEMKKQI QLQLKNTLKA LENMQPLQIE QKFLELHFDI DQAKIAFFQC IKNDSRNSEK  60
   61 LVDILCQRLN FNFDKRAKEM NLDLRVHSLD VEDYIELTDN KEFKNLISSG VEKVTRSQKD 120
  121 LFTLKYKRVQ RIVPHNDTLI ELFDQDIVMH MSELQLVLTP RSVLTLMNYA MLTFTDPNAP 180
  181 EMPADVLRHN KEDRDDAPQK INMKIKMEAV NVIFNDDSIK LATLVLSAGE FTMVLLPERY 240
  241 NINLKLGGLE LTDETNESFS RDSVFRKIIQ MKGQELVELS YESFDPATNT KDYDSFLKYS 300
  301 TGSMHVNFIE SAVNRMVNFF AKFQKSKVSF DRARLAAYNQ APSIDAVNNM KMDIVIKAPI 360
  361 IQFP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [1228-1353]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KLVGTQENNY DTMRFYLGEF FIENKFSVID ESHKINHIKL GVREGQLSSN LNFDGSSQQL  60
   61 YLVENIGLLF NIDRDPLPQD DTPELKVTSN FESFALDLTE NQLTYLLEIS NKVSSAFNIT 120
  121 DENSGE

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [1354-1739]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGGKGEIKSP SPDPASLSSE SERTATPQSL QGSNKSNIKN PEQKYLDFSF KAPKIALTLY  60
   61 NKTKGVTSLN DCGLTRIMFQ DIGCSLGLKN DGTVDGQAHV AAFRIEDVRN IKDNKHTELI 120
  121 PKSKNKEYQF VANISRKNLE VGRLLNISMT MDSPKMILAM DYLVSLKEFF DAIMSKSHEN 180
  181 NLYYPENTNQ KPENKAIVES VQEGGDVTKI QYSVNIIETA LILLADPCDM NSEAISFKIG 240
  241 QFLVTDQNIM TVAANNVGIF LFKMNSSEEK LRLLDDFSSS LTIDKRNSTP QTLMTNIQLS 300
  301 VQPLLMRISL RDIRLAMLIF KRVTTLLNKM TEKEDNGEEE ESTDKIQFSH EFERKLAVLD 360
  361 PSILGERSRA SQSSDSESIE VPTAIL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #7
Region A:
Residues: [1740-1864]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNETFNADLG GLRFILIGDV HEMPILDMNV NEITASAKDW STDFEALASL ETYVNIFNYS  60
   61 RSSWEPLLEM IPITFHLSKG HSEMDPAFSF DILTQRIAEI TLSARSIAML SHIPASLTEE 120
  121 LPLAS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #8
Region A:
Residues: [1865-2169]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RVSQKPYQLV NDTELDFDVW IQDKTTEDNK NEVVLLKANT SLPWEFEDWR SIREKLDIDK  60
   61 SKNILGVCVS GQNYKTIMNI DATTEGENLH VLSPPRNNVH NRIVCEARCD ENNVKIITFR 120
  121 STLVIENTTS TEIELLVDSK DPNKPSLKYA IKPHQSKSVP VEYAYDSDIR IRPASEDIYD 180
  181 WSQQTLSWKS LLSNQMSIFC SSKEDSNQRF HFEIGAKYDE REPLAKIFPH MKIVVSASMT 240
  241 IENLLPADIN FSIFDKREEK RTDFLKTGES MEVHHISLDS FLLMSVQPLQ DEASASKPSI 300
  301 VNTPH

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #9
Region A:
Residues: [2170-2278]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSPLNPEDSL SLTLSGGQNL LLKLDYKNID GTRSKVIRIY SPYIIMNSTD RELYIQSSLL  60
   61 NIAQSKILLE NEKRYTIPKM FSFDKEDDKS NRARIRFKES EWSSKLSFD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [2279-2541]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AIGQSFDASV RIKNKEQESN LGINISEGKG KYLLSKVIEI APRYIISNTL DIPIEVCETG  60
   61 SMDVQQIESN ITKPLYRMRN IVDKQLVLKF LGGDSNWSQP FFIKNVGVTY LKVLKNSRHK 120
  121 LLKIEILLDK ATIFIRIKDG GDRWPFSIRN FSDHDFIFYQ RDPRKVSDPY KDDQSNESSS 180
  181 RSFKPIFYRI PSKSIMPYAW DFPTAKEKYL VLESGTRTRE VRLAEIGELP PLRLDKRSKD 240
  241 KPAPIVGLHV VADDDMQALV IVN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #11
Region A:
Residues: [2542-2619]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YKANVGLYKL KTASATTTSS VSVNSSVTDG FVQKDEDEKV NTQIVVSFKG VGISLINGRL  60
   61 QELLYINMRG IELRYNES

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.851 b.55.2 Description not found.

Predicted Domain #12
Region A:
Residues: [2620-3021]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KAYQTFSWKM KWMQIDNQLF SGNYSNILYP TEIPYTEKEI ENHPVISGSI SKVNDSLQAV  60
   61 PYFKHVTLLI QEFSIQLDED MLYAMMDFIK FPGSPWIMDS RDYKYDEEIQ LPDVSELKTA 120
  121 GDIYFEIFHI QPTVLHLSFI RSDEISPGLA EETEESFSSS LYYVHMFAMT LGNINEAPVK 180
  181 VNSLFMDNVR VPLPILMDHI ERHYTTQFVY QIHKILGSAD CFGNPVGLFN TISSGVWDLF 240
  241 YEPYQGYMMN DRPQEIGIHL AKGGLSFAKK TVFGLSDSMS KFTGSMAKGL SVTQDLEFQR 300
  301 VRRLQQRINK NNRNALANSA QSFASTLGSG LSGIALDPYK AMQKEGAAGF LKGLGKGIVG 360
  361 LPTKTAIGFL DLTSNLSQGV KSTTTVLDMQ KGCRVRLPRY VD

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #13
Region A:
Residues: [3022-3144]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HDQIIKPYDL REAQGQYWLK TVNGGVFMND EYLSHVILPG KELAVIVSMQ HIAEVQMATQ  60
   61 ELMWSTGYPS IQGITLERSG LQIKLKSQSE YFIPISDPEE RRSLYRNIAI AVREYNKYCE 120
  121 AIL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.841 b.55.1 PH domain-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle