| Protein: | ORC3 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 616 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORC3.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..616] | [1..616] |
|
|
0.005 | [37..479] | [241..668] |
|
Region A: Residues: [1-122] |
1 11 21 31 41 51
| | | | | |
1 MSDLNQSKKM NVSEFADAQR SHYTVYPSLP QSNKNDKHIP FVKLLSGKES EVNVEKRWEL 60
61 YHQLHSHFHD QVDHIIDNIE ADLKAEISDL LYSETTQKRR CFNTIFLLGS DSTTKIELKD 120
121 ES
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.599 | b.1.18 | E set domains |
| View | Download | 0.621 | a.7.1 | Spectrin repeat |
| View | Download | 0.621 | a.7.1 | Spectrin repeat |
| View | Download | 0.527 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.582 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.570 | a.69.1 | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| View | Download | 0.564 | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.570 | a.69.1 | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| View | Download | 0.564 | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.703 | b.2.4 | Alpha-macroglobulin receptor domain |
| View | Download | 0.571 | a.118.13 | Arp2/3 complex 16 kDa subunit ARPC5 |
| View | Download | 0.571 | a.118.13 | Arp2/3 complex 16 kDa subunit ARPC5 |
| View | Download | 0.563 | a.7.1 | Spectrin repeat |
| View | Download | 0.509 | d.58.9 | RuBisCO, large subunit, small (N-terminal) domain |
| View | Download | 0.489 | a.66.1 | Transducin (alpha subunit), insertion domain |
| View | Download | 0.481 | a.26.1 | 4-helical cytokines |
| View | Download | 0.472 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.462 | a.7.1 | Spectrin repeat |
| View | Download | 0.454 | a.1.1 | Globin-like |
| View | Download | 0.452 | a.29.2 | Bromodomain |
| View | Download | 0.450 | c.47.1 | Thioredoxin-like |
| View | Download | 0.448 | d.122.1 | ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase |
| View | Download | 0.444 | b.1.7 | Actinoxanthin-like |
| View | Download | 0.442 | a.177.1 | Sigma2 domain of RNA polymerase sigma factors |
| View | Download | 0.442 | a.24.3 | Cytochromes |
| View | Download | 0.437 | a.118.8 | TPR-like |
| View | Download | 0.435 | b.24.1 | Hyaluronate lyase-like, C-terminal domain |
| View | Download | 0.428 | b.7.1 | C2 domain (Calcium/lipid-binding domain, CaLB) |
| View | Download | 0.427 | c.49.1 | Pyruvate kinase, C-terminal domain |
| View | Download | 0.426 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.426 | g.45.1 | Pyk2-associated protein beta ARF-GAP domain |
| View | Download | 0.424 | a.74.1 | Cyclin-like |
| View | Download | 0.422 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.414 | c.47.1 | Thioredoxin-like |
| View | Download | 0.411 | a.46.1 | Methionine synthase domain |
| View | Download | 0.407 | a.24.14 | FAT domain of focal adhesion kinase |
| View | Download | 0.407 | a.4.1 | Homeodomain-like |
| View | Download | 0.391 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.390 | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.390 | b.1.1 | Immunoglobulin |
| View | Download | 0.388 | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.387 | c.47.1 | Thioredoxin-like |
| View | Download | 0.387 | d.32.1 | Glyoxalase/Bleomycin resistance protein/Dihydroxybiphenyl dioxygenase |
| View | Download | 0.382 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.379 | f.32.1 | a domain/subunit of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase) |
| View | Download | 0.377 | d.91.1 | N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 |
| View | Download | 0.371 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.368 | a.26.1 | 4-helical cytokines |
| View | Download | 0.365 | d.236.1 | DNA-binding protein Tfx |
| View | Download | 0.364 | a.78.1 | Fatty acid responsive transcription factor FadR, C-terminal domain |
| View | Download | 0.362 | d.110.3 | PYP-like sensor domain (PAS domain) |
| View | Download | 0.362 | c.53.1 | Resolvase-like |
| View | Download | 0.361 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.360 | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.359 | d.212.1 | TolA/TonB C-terminal domain |
| View | Download | 0.359 | d.15.6 | Superantigen toxins, C-terminal domain |
| View | Download | 0.356 | d.33.1 | Bacterial protein-export protein SecB |
| View | Download | 0.355 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.351 | a.5.4 | Elongation factor TFIIS domain 2 |
| View | Download | 0.351 | c.23.5 | Flavoproteins |
| View | Download | 0.347 | b.1.1 | Immunoglobulin |
| View | Download | 0.342 | b.1.5 | Transglutaminase, two C-terminal domains |
| View | Download | 0.338 | a.26.1 | 4-helical cytokines |
| View | Download | 0.335 | a.75.1 | Ribosomal protein S7 |
| View | Download | 0.333 | b.1.6 | Cadherin |
| View | Download | 0.331 | a.7.3 | Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain |
| View | Download | 0.330 | f.21.2 | Fumarate reductase respiratory complex transmembrane subunits |
| View | Download | 0.328 | b.40.4 | Nucleic acid-binding proteins |
| View | Download | 0.326 | a.47.2 | t-snare proteins |
| View | Download | 0.325 | a.26.1 | 4-helical cytokines |
| View | Download | 0.324 | b.1.5 | Transglutaminase, two C-terminal domains |
| View | Download | 0.320 | a.26.1 | 4-helical cytokines |
| View | Download | 0.319 | a.133.1 | Phospholipase A2, PLA2 |
| View | Download | 0.319 | d.162.1 | LDH C-terminal domain-like |
| View | Download | 0.318 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.315 | b.59.1 | XRCC4, N-terminal domain |
| View | Download | 0.315 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.314 | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.312 | a.66.1 | Transducin (alpha subunit), insertion domain |
| View | Download | 0.312 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.309 | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.305 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.297 | c.52.1 | Restriction endonuclease-like |
| View | Download | 0.292 | d.81.1 | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |
| View | Download | 0.292 | a.118.14 | FliG |
| View | Download | 0.292 | a.18.1 | T4 endonuclease V |
| View | Download | 0.288 | d.84.1 | Subtilisin inhibitor |
| View | Download | 0.282 | d.60.1 | Probable bacterial effector-binding domain |
| View | Download | 0.281 | d.91.1 | N-terminal domain of eukaryotic peptide chain release factor subunit 1, ERF1 |
| View | Download | 0.275 | a.4.3 | ARID-like |
| View | Download | 0.275 | a.2.7 | tRNA-binding arm |
| View | Download | 0.272 | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.270 | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.268 | a.26.1 | 4-helical cytokines |
| View | Download | 0.268 | a.26.1 | 4-helical cytokines |
| View | Download | 0.266 | d.15.4 | 2Fe-2S ferredoxin-like |
| View | Download | 0.263 | a.23.4 | Mitochondrial import receptor subunit Tom20 |
| View | Download | 0.263 | a.118.1 | ARM repeat |
| View | Download | 0.262 | d.123.1 | Sporulation responce regulatory protein Spo0B |
| View | Download | 0.259 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.256 | a.1.1 | Globin-like |
| View | Download | 0.255 | a.47.2 | t-snare proteins |
| View | Download | 0.253 | a.26.1 | 4-helical cytokines |
| View | Download | 0.253 | d.96.1 | Tetrahydrobiopterin biosynthesis enzymes-like |
| View | Download | 0.247 | a.63.1 | Apolipophorin-III |
| View | Download | 0.245 | a.22.1 | Histone-fold |
| View | Download | 0.245 | a.4.3 | ARID-like |
| View | Download | 0.241 | d.81.1 | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |
| View | Download | 0.239 | a.1.1 | Globin-like |
| View | Download | 0.239 | b.1.2 | Fibronectin type III |
| View | Download | 0.239 | d.81.1 | Glyceraldehyde-3-phosphate dehydrogenase-like, C-terminal domain |
| View | Download | 0.236 | a.126.1 | Serum albumin-like |
| View | Download | 0.235 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.235 | c.3.1 | FAD/NAD(P)-binding domain |
| View | Download | 0.234 | d.162.1 | LDH C-terminal domain-like |
| View | Download | 0.231 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.230 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.228 | d.16.1 | FAD-linked reductases, C-terminal domain |
| View | Download | 0.228 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.226 | a.2.3 | Chaperone J-domain |
| View | Download | 0.226 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.226 | a.116.1 | GTPase activation domain, GAP |
| View | Download | 0.225 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.222 | c.26.2 | Adenine nucleotide alpha hydrolases-like |
| View | Download | 0.222 | a.22.1 | Histone-fold |
| View | Download | 0.220 | a.126.1 | Serum albumin-like |
| View | Download | 0.219 | a.62.1 | Hepatitis B viral capsid (hbcag) |
| View | Download | 0.218 | a.24.1 | Apolipoprotein |
| View | Download | 0.217 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.217 | a.25.1 | Ferritin-like |
| View | Download | 0.214 | d.13.1 | HIT-like |
| View | Download | 0.213 | a.77.1 | DEATH domain |
| View | Download | 0.211 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.209 | a.29.3 | Acyl-CoA dehydrogenase C-terminal domain-like |
| View | Download | 0.208 | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.208 | a.24.2 | Aspartate receptor, ligand-binding domain |
| View | Download | 0.207 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.205 | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.205 | a.39.1 | EF-hand |
| View | Download | 0.204 | a.24.1 | Apolipoprotein |
| View | Download | 0.204 | a.130.1 | Chorismate mutase II |
| View | Download | 0.202 | a.2.1 | GreA transcript cleavage protein, N-terminal domain |
| View | Download | 0.202 | a.73.1 | Retrovirus capsid protein, N-terminal core domain |
| View | Download | 0.201 | a.24.12 | Outer surface protein C (OspC) |
| View | Download | 0.200 | b.6.1 | Cupredoxins |
|
Region A: Residues: [123-144] |
1 11 21 31 41 51
| | | | | |
1 SRYNVLIELT PKESPNVRMM LR
|
|
Region B: Residues: [156-289] |
1 11 21 31 41 51
| | | | | |
1 AEEHPTIKYE DINDEDGDFT EQNNDVSYDL SLVENFKRLF GKDLAMVFNF KDVDSINFNT 60
61 LDNFIILLKS AFKYDHVKIS LIFNINTNLS NIEKNLRQST IRLLKRNYHK LDVSSNKGFK 120
121 YGNQIFQSFL DTVD
|
| Detection Method: | |
| Confidence: | 7.56 |
| Match: | 1n1bA |
| Description: | (+)-bornyl diphosphate synthase |
Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [145-155] |
1 11 21 31 41 51
| | | | | |
1 RSMYKLYSAA D
|
|
Region B: Residues: [290-506] |
1 11 21 31 41 51
| | | | | |
1 GKLNLSDRFV EFILSKMANN TNHNLQLLTK MLDYSLMSYF FQNAFSVFID PVNVDFLNDD 60
61 YLKILSRCPT FMFFVEGLIK QHAPADEILS LLTNKNRGLE EFFVEFLVRE NPINGHAKFV 120
121 ARFLEEELNI TNFNLIELYH NLLIGKLDSY LDRWSACKEY KDRLHFEPID TIFQELFTLD 180
181 NRSGLLTQSI FPSYKSNIED NLLSWEQVLP SLDKENY
|
| Detection Method: | |
| Confidence: | 7.56 |
| Match: | 1n1bA |
| Description: | (+)-bornyl diphosphate synthase |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [507-616] |
1 11 21 31 41 51
| | | | | |
1 DTLSGDLDKI MAPVLGQLFK LYREANMTIN IYDFYIAFRE TLPKEEILNF IRKDPSNTKL 60
61 LELAETPDAF DKVALILFMQ AIFAFENMGL IKFQSTKSYD LVEKCVWRGI
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.447 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.447 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.404 | a.1.1 | Globin-like |
| View | Download | 0.404 | a.1.1 | Globin-like |
| View | Download | 0.408 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.408 | a.48.3 | Conserved domain common to transcription factors TFIIS, elongin A, CRSP70 |
| View | Download | 0.385 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.385 | a.76.1 | Iron-dependent represor protein, dimerization domain |
| View | Download | 0.379 | a.182.1 | GatB/YqeY domain |
| View | Download | 0.379 | a.182.1 | GatB/YqeY domain |
| View | Download | 0.365 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.348 | d.49.1 | Signal recognition particle alu RNA binding heterodimer, SRP9/14 |
| View | Download | 0.348 | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.346 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.342 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.312 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.294 | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.290 | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.275 | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.257 | f.31.1 | Photosystem I reaction center subunit XI, PsaL |
| View | Download | 0.257 | a.1.1 | Globin-like |
| View | Download | 0.252 | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.252 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.246 | a.24.15 | FAD-dependent thiol oxidase |
| View | Download | 0.243 | d.56.1 | GroEL-intermediate domain like |
| View | Download | 0.242 | a.118.14 | FliG |
| View | Download | 0.236 | a.69.2 | Ypt/Rab-GAP domain of gyp1p |
| View | Download | 0.235 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.232 | f.18.1 | F1F0 ATP synthase subunit A |
| View | Download | 0.224 | c.30.1 | PreATP-grasp domain |
| View | Download | 0.220 | d.58.20 | NAD-binding domain of HMG-CoA reductase |
| View | Download | 0.219 | a.24.16 | Nucleotidyltransferase substrate binding subunit/domain |
| View | Download | 0.216 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.216 | a.74.1 | Cyclin-like |
| View | Download | 0.215 | a.28.3 | Retrovirus capsid protein C-terminal domain |
| View | Download | 0.213 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.209 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.209 | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.208 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.204 | a.24.3 | Cytochromes |
| View | Download | 0.203 | a.74.1 | Cyclin-like |
| View | Download | 0.202 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
