YRC Public Data Repository - Protein Structure Prediction

Protein:	YKR106W
Organism:	Saccharomyces cerevisiae
Length:	615 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKR106W.

Description	E-value	Query Range	Subject Range
GEX1_YEAST - Glutathione exchanger 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GEX1 PE=1 SV=4 YCL073C - Protein of unconfirmed function; displays a topology characteristic of the Major Facilitators Superf...	0.0	[1..615]	[1..615]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[1..615]	[1..615]
gi\|19386936 - gi\|19386936\|gb\|AAL87047.1\|AF448056_3 putative dothistromin transporter [Mycosphaerella pini] gi\|19386936 - gi\|19386936\|gb\|AAL87047.1\|AF448056_3 putative dothistromin transporter [Mycosphaerella pini]	3.0E-87	[18..609]	[7..602]
gi\|21225257, gi\|... - gi\|7649556\|emb\|CAB89031.1\| putative membrane transport protein. [Streptomyces coelicolor A3(2)], gi\|...	4.0E-87	[26..577]	[2..523]
gi\|16944692 - gi\|16944692\|emb\|CAC28808.2\| related to tetracycline efflux protein (otrb) [Neurospora crassa]	1.0E-83	[14..598]	[3..580]

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Predicted Domain #1

Region A:
Residues: [1-406]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSVVGASS NKKSGIRQSC EIIERERHSN DDTYSMTSTF FKLKENEIMS AQFDSLKYKI  60
   61 LLISTAFVCG FGISLDYTLR STYTGYATNS YSEHSLLSTV QVINAVVSVG SQVVYSRLSD 120
  121 HFGRLRLFLV ATIFYIMGTI IQSQATRLTM YAAGSVFYNC GYVGTNLLLT LILSDFSSLK 180
  181 WRMFYQYASY WPYIIIPWIS GNIITAANPQ KNWSWNIAMW AFIYPLSTLP IIFLILYMKY 240
  241 KSSKTAEWRS LKEQARKERT GGLFENLVFL FWKLDIVGIL LITVSLGCIL VPLTLANETS 300
  301 QKWHNSKIIA TLVSGGCLFF IFLYWEAKFA KSPLLPFKLL SDRGIWAPLG VTFFNFFTFF 360
  361 ISCDYLYPVL LVSMKESSTS AARIVNLPDF VAATASPFYS LLVAKT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	5.522879
Match:	1ja5A_
Description:	No description for 1ja5A_ was found.

Predicted Domain #2

Region A:
Residues: [407-615]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RKLKLSVIGG CAAWMVCMGL FYKYRGGSGS HEGVIAASVI MGLSGLLCSN SVIVILQAMT  60
   61 THSRMAVITG IQYTFSKLGA AIGASVSGAI WTQTMPNQLY KNLGNDTLAE IAYASPYTFI 120
  121 SDYPWGSPER DAVVESYRYV QRIIMTVGLA CTVPFFTFTM FMRNPELIDK ATHEEFTEDG 180
  181 LVVLPDEENI FSQIKALFRH NRSNKKSGC

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [531-615]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WGSPERDAVV ESYRYVQRII MTVGLACTVP FFTFTMFMRN PELIDKATHE EFTEDGLVVL  60
   61 PDEENIFSQI KALFRHNRSN KKSGC

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits