| Protein: | SIR1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 678 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SIR1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..678] | [1..678] |
|
Region A: Residues: [1-678] |
1 11 21 31 41 51
| | | | | |
1 MRTIMSIITR RYKQLKNYKI ISKKMLQINS RLAVIDGWLV DTVKRKPINF RSPEVRLLLP 60
61 NDDDYKKLSQ QNLVDWTRLK KDSNSVLVGV KSMELFKHIK LVLREFFLLE DGRIILKRIR 120
121 SKLRYKVVKK LTCKCCRLYL PKWGTVYIHP MLKDKEKPLA GVCEFSLDVN PDREYPLIEI 180
181 NVSHQYIIIE GFLLYLNERR LYRWNDNNLR SQVGLTKWAH LRKTYNPVSL DILYSLNSNF 240
241 YFVKDDLLFQ LLGKRVFVKF CKVMENGKCG KAPLWYRVKR TTTAKATHIA YAISNSTAPD 300
301 SFKSKNNDYR FIVREKPIVE NTISNLDYSD IKKQQFTEAE VVKRKISADI SQIENVHTQF 360
361 NSQKEKNNIR VNKVSSEVLD QISKFPVSRV TLLLMSAGQD KNYIELVEEL ARRLEKICIE 420
421 KTTQSLEEIR DTFQANPEMQ ASFDKEYYQS IEEYKITLEL IKEDLLITLI KQMENMWAAE 480
481 KKFSTEEEYV SPRFLVADGF LIDLAEEKPI NPKDPRLLTL LKDHQRAMID QMNLVKWNDF 540
541 KKYQDPIPLK AKTLFKFCKQ IKKKFLRGAD FKLHTLPTEA NLKYEPERMT VLCSCVPILL 600
601 DDQTVQYLYD DSIIPEFEAT SSYATKQSKC GRKMSLQMEP DLLFQEAIRR MRHLTAYDVL 660
661 RRNYIAAFEE LYMGNCND
|
| Detection Method: |  |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [154-298] |
1 11 21 31 41 51
| | | | | |
1 DKEKPLAGVC EFSLDVNPDR EYPLIEINVS HQYIIIEGFL LYLNERRLYR WNDNNLRSQV 60
61 GLTKWAHLRK TYNPVSLDIL YSLNSNFYFV KDDLLFQLLG KRVFVKFCKV MENGKCGKAP 120
121 LWYRVKRTTT AKATHIAYAI SNSTA
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [299-483] |
1 11 21 31 41 51
| | | | | |
1 PDSFKSKNND YRFIVREKPI VENTISNLDY SDIKKQQFTE AEVVKRKISA DISQIENVHT 60
61 QFNSQKEKNN IRVNKVSSEV LDQISKFPVS RVTLLLMSAG QDKNYIELVE ELARRLEKIC 120
121 IEKTTQSLEE IRDTFQANPE MQASFDKEYY QSIEEYKITL ELIKEDLLIT LIKQMENMWA 180
181 AEKKF
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [484-678] |
1 11 21 31 41 51
| | | | | |
1 STEEEYVSPR FLVADGFLID LAEEKPINPK DPRLLTLLKD HQRAMIDQMN LVKWNDFKKY 60
61 QDPIPLKAKT LFKFCKQIKK KFLRGADFKL HTLPTEANLK YEPERMTVLC SCVPILLDDQ 120
121 TVQYLYDDSI IPEFEATSSY ATKQSKCGRK MSLQMEPDLL FQEAIRRMRH LTAYDVLRRN 180
181 YIAAFEELYM GNCND
|
| Detection Method: | |
| Confidence: | 80.09691 |
| Match: | 1z1aA |
| Description: | S. cerevisiae Sir1 ORC-interaction domain |
Matching Structure (courtesy of the PDB): |
|
