YRC Public Data Repository - Protein Structure Prediction

Protein:	YKR051W
Organism:	Saccharomyces cerevisiae
Length:	418 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKR051W.

Description	E-value	Query Range	Subject Range
gi\|42563535, gi\|... - gi\|6671963\|gb\|AAF23222.1\|AC013454_9 unknown protein [Arabidopsis thaliana], gi\|62320520\|dbj\|BAD95090...	399.0	[0..5]	[313..4]
T184B_BOVIN - Transmembrane protein 184B OS=Bos taurus GN=TMEM184B PE=2 SV=1	397.0	[0..13]	[317..49]
TMEM184B - transmembrane protein 184B HGNC:1310\|Ensemb... - protein 184B gi\|109451086, gi... - gi\|109451664\|emb\|CAK54703.1\| C22orf5 [synthetic construct], gi\|109451086\|emb\|CAK54404.1\| C22orf5 [sy...	396.0	[0..13]	[317..49]
gi\|109482563, gi... - gi\|109482563\|ref\|XP_001076493.1\| PREDICTED: similar to Putative MAP kinase-activating protein C22orf...	396.0	[0..14]	[317..114]
gi\|73969645 - gi\|73969645\|ref\|XP_538375.2\| PREDICTED: similar to Putative MAP kinase-activating protein C22orf5 [C...	395.0	[0..13]	[317..49]
T184B_MOUSE - Transmembrane protein 184B OS=Mus musculus GN=Tmem184b PE=2 SV=1	393.0	[0..13]	[317..49]
gi\|109094178, gi... - gi\|109094180\|ref\|XP_001093546.1\| PREDICTED: chromosome 22 open reading frame 5 isoform 2 [Macaca mul...	392.0	[0..13]	[317..49]
gi\|60099007, gi\|... - gi\|71896895\|ref\|NP_001025930.1\| transmembrane protein 184B [Gallus gallus], gi\|60099007\|emb\|CAH65334...	392.0	[0..13]	[317..52]

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Predicted Domain #1

Region A:
Residues: [1-317]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MENKLLCWWL YWPCVYSSII ATIISFYTIT RHLLNYRKPY EQRLSIRILL LVPIFSVSCA  60
   61 SGIIKPEAAQ FYVDPIREFY EAFVIYTFFT FLTLLLGGER NIITVLSLNH APTRHPIPLI 120
  121 GKICKPIDLS DPFDFLFVKK GILQYVWFKP FYCFGTLICS AWKLPKFEIF LNVFYNISVT 180
  181 WSLYSLALFW KCLYPELTPY KPWLKFLCVK LIIFASYWQS IIIQGLVVTG KLGTGNQDRT 240
  241 SGYVYKNGLL CIEMVPFAIL HAVAFPWNKY TAFSIPYGAR MKFIYALKDF LGCGDLIWDF 300
  301 KQTLFAGPLY YNYRNFD

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	158.309804
Match:	PF03619
Description:	Domain of unknown function

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [318-418]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PEAMDLLSTR QQSGATMERL KHGLRFTDNG RNSYWVAYGS IDNNLVPESI EESWEDDIAG  60
   61 QRTFPEDPNY PVVHDYTMGH RYSRSMNDLR RDVQSRSSMA C

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.445	b.1.2	Fibronectin type III
View	Download	0.372	d.87.2	CO dehydrogenase flavoprotein C-terminal domain-like
View	Download	0.299	a.4.2	Methylated DNA-protein cysteine methyltransferase, C-terminal domain
View	Download	0.290	c.55.1	Actin-like ATPase domain
View	Download	0.270	d.109.1	Actin depolymerizing proteins
View	Download	0.249	a.100.1	6-phosphogluconate dehydrogenase C-terminal domain-like
View	Download	0.220	d.109.1	Actin depolymerizing proteins
View	Download	0.204	a.60.9	lambda integrase-like, N-terminal domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits