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View Structure Prediction Details

Protein: YKR015C
Organism: Saccharomyces cerevisiae
Length: 568 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YKR015C.

Description E-value Query
Range
Subject
Range
gi|7494165, gi|9... - gi|914921|gb|AAA89134.1| PfEMP1 variant 2 of strain MC, pir||T18396 erythrocyte membrane protein var...
295.0 [0..162] [544..66]
gi|23613363, gi|... - gi|7670005|emb|CAB89209.1| erythrocyte membrane protein 1, PfEMP1 [Plasmodium falciparum 3D7], gi|23...
282.0 [0..168] [544..74]

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Predicted Domain #1
Region A:
Residues: [1-111]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFLDYSGYEA LTEINSSFGK YVLLLQQFEG CRSLKDRLQM LKDLGREFMI FENLNVEDFR  60
   61 ESKNMIHRFY TMVISLRQIM EIGPLVRRSP AVLVVEFDCP VEDCLDELDP L

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [112-180]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPLNRAFIFI HKQWTYYHQY YIVEKVKKVI LDMAPVKEDD WSILHKVVYS EGFVERRYKK  60
   61 KKYLGDIYI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [181-568]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQPLMKSNKI TTISNFSQLT KISNVRVYRF NATAACDPQN LNKKNLSIKE LKDKDLPNLI  60
   61 WTLEPEKFYV DMRPYKEHEE RKKRREEEAK VRMQGEEQEN IMIERKKMDS IEVEASSGLK 120
  121 NIIKTPLANR VVNTFNNCAA VVIGYVTEVD KVKDDNEEKN NDRPKIANDG IAQKSRSESE 180
  181 DNAGTPMENA YFQPEPQDND QNNISWNTTM KDIDPIYMSE RCARVWRKEQ QMLGLEKAQT 240
  241 FEKKYCKDQM VMDENQVEEP GKHSERHTKN QVVRPRTKIA SSASKNDNSN NKNSKSCKNC 300
  301 HKEEAHGLVR EYLKIKLNIS PHGERNQRTK DKRKCIMKYN ASSNNINKMP GESEVLGSTI 360
  361 LTDIHFKDVV TVKFRDFKAK FRKVKINA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 33.69897
Match: 1zrlA
Description: Crystal structure of EBA-175 Region II (RII)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle