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View Structure Prediction Details

Protein: RSC4
Organism: Saccharomyces cerevisiae
Length: 625 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RSC4.

Description E-value Query
Range
Subject
Range
RSC4 - Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; disp...
0.0 [1..625] [1..625]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
4.0E-61 [40..298] [10..294]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
9.0E-55 [18..303] [1367..1638]
gi|12083875, gi|... - gi|12083875|gb|AAG48933.1|AF177387_1 polybromo-1 [Homo sapiens], gi|119585646|gb|EAW65242.1| polybro...
2.0E-54 [1..409] [480..866]

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Predicted Domain #1
Region A:
Residues: [1-163]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVVKKRKLAT EAGGSDERPK YLPGKHPKNQ EKTPHVDYNA PLNPKSELFL DDWHIPKFNR  60
   61 FISFTLDVLI DKYKDIFKDF IKLPSRKFHP QYYYKIQQPM SINEIKSRDY EYEDGPSNFL 120
  121 LDVELLTKNC QAYNEYDSLI VKNSMQVVML IEFEVLKAKN LKR

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 18.721246
Match: PF00439
Description: Bromodomain

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [164-338]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NYLINSEVKA KLLHYLNKLV DATEKKINQA LLGASSPKNL DDKVKLSEPF MELVDKDELP  60
   61 EYYEIVHSPM ALSIVKQNLE IGQYSKIYDF IIDMLLVFQN AHIFNDPSAL IYKDATTLTN 120
  121 YFNYLIQKEF FPELQDLNER GEINLEFDKF EFENYLAIGG GGPAAAGALA ISALD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 126.512579
Match: 1e6iA_
Description: GCN5
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [339-458]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDIEPESNRE DLIDQADYDF NHFEGLGNGY NRSLLTEDYL LNPNNFKKLI AIPETVQSEV  60
   61 KNERSTTSDI EKTNSLESEH LKIPKYNVIK SMQKEMQSLS EQHTMEYKPY KLIQQIYIFS 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.334 N/A N/A a.1.1 Globin-like
View Download 0.300 N/A N/A d.58.26 GHMP Kinase, C-terminal domain
View Download 0.277 N/A N/A a.138.1 Multiheme cytochromes
View Download 0.237 N/A N/A c.84.1 Phosphoglucomutase, first 3 domains
View Download 0.214 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.207 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.205 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore

Predicted Domain #4
Region A:
Residues: [459-625]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SKNLYSQATK PLLGSRPSCN QNWVEYIFNG NELSQNENAF SFMLQPMQTF LTLQSHLTSS  60
   61 LKDTETLLTI NKEPVKSRTS NVNSNLSQPQ QQENDVIGND TKQDIENLTI GGGNNNDIVG 120
  121 NDNDKRNNIT EIFDIRLSEG LNHLMFRCED KISHETEFMN FWINVLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.300 d.58.26 GHMP Kinase, C-terminal domain
View Download 0.207 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle