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View Structure Prediction Details

Protein: AIM27
Organism: Saccharomyces cerevisiae
Length: 260 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AIM27.

Description E-value Query
Range
Subject
Range
gi|5823570, gi|2... - gi|7267961|emb|CAB78302.1| putative protein [Arabidopsis thaliana], gi|5823570|emb|CAB53752.1| putat...
1.0E-79 [27..245] [2..214]
gi|194130449, gi... - gi|195339929|ref|XP_002036569.1| GM11489 [Drosophila sechellia], gi|194130449|gb|EDW52492.1| GM11489...
gi|194191018, gi... - gi|195578311|ref|XP_002079009.1| GD22233 [Drosophila simulans], gi|194191018|gb|EDX04594.1| GD22233 ...
CG6750-PA - This gene is referred to in FlyBase by the symbol Dmel\CG6750 (CG6750, FBgn0032292). It is a protein...
gi|220950088, gi... - gi|220959142|gb|ACL92114.1| CG6750-PA [synthetic construct], gi|220950088|gb|ACL87587.1| CG6750-PA [...
1.0E-77 [29..244] [3..211]
EMC3_RAT - ER membrane protein complex subunit 3 OS=Rattus norvegicus GN=Emc3 PE=2 SV=3
EMC3_MOUSE - ER membrane protein complex subunit 3 OS=Mus musculus GN=Emc3 PE=1 SV=3
5.0E-76 [28..241] [4..213]
ENSCJAT00000031683 - null
gi|55619789 - gi|55619789|ref|XP_516272.1| PREDICTED: hypothetical protein isoform 3 [Pan troglodytes]
TM111_PONPY - Transmembrane protein 111 - Pongo pygmaeus (Orangutan)
tr|M3WUY6|M3WUY6... - ER membrane protein complex subunit 3 OS=Felis catus GN=EMC3 PE=3 SV=1
gi|149728297 - gi|149728297|ref|XP_001494113.1| PREDICTED: similar to Transmembrane protein 111 [Equus caballus]
EMC3_PONAB - ER membrane protein complex subunit 3 OS=Pongo abelii GN=EMC3 PE=2 SV=3
TMEM111 - transmembrane protein 111
gi|57100904 - gi|57100904|ref|XP_533744.1| PREDICTED: similar to 30 kDa protein isoform 1 [Canis familiaris]
5.0E-76 [28..241] [4..213]
CE22698 - status:Partially_confirmed UniProt:Q9U1X6 protein_id:CAB60598.1
2.0E-74 [29..244] [3..216]
SPBC1711.03 - conserved eukaryotic protein
YNY3_SCHPO - ER membrane protein complex subunit 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPBC...
2.0E-73 [29..244] [3..215]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTINQHLQQL LFNRIDKTTS SIQQARAPQM LLDDQLKYWV LLPISIVMVL TGVLKQYIMT  60
   61 LITGSSANEA QPRVKLTEWQ YLQWAQLLIG NGGNLSSDAF AAKKEFLVKD LTEERHLAKA 120
  121 KQQDGSQAGE VP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.634 a.29.3 Acyl-CoA dehydrogenase C-terminal domain-like
View Download 0.514 a.24.17 Group V grass pollen allergen
View Download 0.479 a.2.7 tRNA-binding arm
View Download 0.435 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.422 a.118.8 TPR-like
View Download 0.400 a.47.2 t-snare proteins
View Download 0.392 a.47.2 t-snare proteins
View Download 0.353 a.118.8 TPR-like
View Download 0.342 c.55.1 Actin-like ATPase domain
View Download 0.339 a.24.9 alpha-catenin/vinculin
View Download 0.334 a.79.1 Antitermination factor NusB
View Download 0.327 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.325 a.7.1 Spectrin repeat
View Download 0.319 a.25.1 Ferritin-like
View Download 0.305 a.26.1 4-helical cytokines
View Download 0.302 a.24.1 Apolipoprotein
View Download 0.299 a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.289 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.288 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.288 a.118.12 Ran-GTPase activating protein 1 (RanGAP1), C-terminal domain
View Download 0.283 f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.278 f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.268 f.14.1 Voltage-gated potassium channels
View Download 0.263 a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.236 a.19.1 Fertilization protein
View Download 0.234 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.234 a.74.1 Cyclin-like
View Download 0.232 a.24.14 FAT domain of focal adhesion kinase
View Download 0.227 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.220 a.63.1 Apolipophorin-III
View Download 0.220 a.1.2 alpha-helical ferredoxin
View Download 0.218 a.1.1 Globin-like
View Download 0.216 a.118.8 TPR-like
View Download 0.214 a.25.1 Ferritin-like
View Download 0.213 a.69.1 C-terminal domain of alpha and beta subunits of F1 ATP synthase
View Download 0.211 a.39.1 EF-hand
View Download 0.209 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.202 a.47.1 STAT
View Download 0.201 a.8.2 Plasmid maintenance system epsilon/zeta, antidote epsilon subunit

Predicted Domain #2
Region A:
Residues: [133-260]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPFNDPSMSN AMMNMAKGNM ASFIPQTIIM WWVNHFFAGF ILMQLPFPLT AKFKEMLQTG  60
   61 IICQDLDVRW VSSISWYFIS VLGLNPVYNL IGLNDQDMGI QAGIGGPQAP KALHNHRLTK 120
  121 QCMRWLTI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.421 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.345 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.340 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.298 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.275 N/A N/A a.74.1 Cyclin-like
View Download 0.257 N/A N/A a.118.8 TPR-like
View Download 0.256 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.243 N/A N/A a.4.12 TrpR-like
View Download 0.237 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.225 N/A N/A d.129.4 Cell-division protein ZipA, C-terminal domain
View Download 0.216 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.212 N/A N/A a.24.9 alpha-catenin/vinculin


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle