YRC Public Data Repository - Protein Structure Prediction

Protein:	SPE1
Organism:	Saccharomyces cerevisiae
Length:	466 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPE1.

Description	E-value	Query Range	Subject Range
DCOR_YEAST - Ornithine decarboxylase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SPE1 PE=1 SV=1 SPE1 - Ornithine decarboxylase, catalyzes the first step in polyamine biosynthesis; degraded in a proteasom...	0.0	[1..466]	[1..466]
ODC1 - ornithine decarboxylase 1 gi\|123998958, gi... - gi\|190690881\|gb\|ACE87215.1\| ornithine decarboxylase 1 protein [synthetic construct], gi\|157929112\|gb...	0.0	[42..463]	[2..411]
DCOR_BOVIN - Ornithine decarboxylase OS=Bos taurus GN=ODC1 PE=2 SV=1	0.0	[45..463]	[5..411]
gi\|6435612 - gi\|6435612\|pdb\|7ODC\|A Chain A, Crystal Structure Ornithine Decarboxylase From Mouse, Truncated 37 Re...	0.0	[45..461]	[5..409]
DCOR_MUSPA - Ornithine decarboxylase OS=Mus pahari GN=Odc1 PE=2 SV=1	0.0	[45..461]	[5..409]
DCOR_RAT - Ornithine decarboxylase OS=Rattus norvegicus GN=Odc1 PE=1 SV=1	0.0	[45..461]	[5..409]
DCOR_CHICK - Ornithine decarboxylase (Fragment) OS=Gallus gallus GN=ODC1 PE=2 SV=1	0.0	[54..461]	[4..399]

Back

Predicted Domain #1

Region A:
Residues: [1-94]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSTQVGNAL SSSTTTLVDL SNSTVTQKKQ YYKDGETLHN LLLELKNNQD LELLPHEQAH  60
   61 PKIFQALKAR IGRINNETCD PGEENSFFIC DLGE

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [457-466]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIVYIDSELD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1026.457575
Match:	7odcA_
Description:	Eukaryotic ornithine decarboxylase (ODC); Eukaryotic ornithine decarboxylase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [95-326]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKRLFNNWVK ELPRIKPFYA VKCNPDTKVL SLLAELGVNF DCASKVEIDR VLSMNISPDR  60
   61 IVYANPCKVA SFIRYAASKN VMKSTFDNVE ELHKIKKFHP ESQLLLRIAT DDSTAQCRLS 120
  121 TKYGCEMENV DVLLKAIKEL GLNLAGVSFH VGSGASDFTS LYKAVRDART VFDKAANEYG 180
  181 LPPLKILDVG GGFQFESFKE STAVLRLALE EFFPVGCGVD IIAEPGRYFV AT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1026.457575
Match:	7odcA_
Description:	Eukaryotic ornithine decarboxylase (ODC); Eukaryotic ornithine decarboxylase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [327-456]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AFTLASHVIA KRKLSENEAM IYTNDGVYGN MNCILFDHQE PHPRTLYHNL EFHYDDFEST  60
   61 TAVLDSINKT RSEYPYKVSI WGPTCDGLDC IAKEYYMKHD VIVGDWFYFP ALGAYTSSAA 120
  121 TQFNGFEQTA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	1026.457575
Match:	7odcA_
Description:	Eukaryotic ornithine decarboxylase (ODC); Eukaryotic ornithine decarboxylase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits