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View Structure Prediction Details

Protein: COY1
Organism: Saccharomyces cerevisiae
Length: 679 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for COY1.

Description E-value Query
Range
Subject
Range
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1
8.0E-73 [29..614] [841..1421]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
5.0E-72 [29..613] [55..634]
gi|179508, gi|10... - sp|P12883|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta), gi|4557773|ref|NP...
7.0E-72 [29..613] [839..1418]
MYH2_BOVIN - Myosin-2 OS=Bos taurus GN=MYH2 PE=2 SV=1
1.0E-71 [29..614] [844..1424]
gi|14250231, gi|... - ref|NP_659210.1| myosin, heavy polypeptide 2, skeletal muscle, adult [Mus musculus], gi|14250231|gb...
1.0E-71 [29..614] [846..1426]

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Predicted Domain #1
Region A:
Residues: [1-359]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTSVYSHAL DIWAKADLTN LQRELDADVI EIKDKETLSL NSRKSLATET KKFKKLEPEE  60
   61 KLNNVNKIIK QYQREIDNLT QRSKFSEKVL FDVYEKLSEA PDPQPLLQSS LEKLGKIDDS 120
  121 KELKEKISYL EDKLAKYADY ETLKSRLLDL EQSSAKTLAK RLTAKTQEIN STWEEKGRNW 180
  181 KEREADLLKQ LTNVQEQNKA LEAKISKNID IEGNGNEDGD QENNQKEVST RIAEYNLVTQ 240
  241 ELETTQARIY QLEKRNEELS GALAKATSEA EKETELHAKE LKLNQLESEN ALLSASYEQE 300
  301 RKSTSHAINE LKEQLNSVVA ESESYKSELE TVRRKLNNYS DYNKIKEELS ALKKIEFGV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 23.0
Match: 1i84S_
Description: Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [360-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NEDDSDNDIR SEDKNDNTFE SSLLSANKKL QATLAEYRSK STAQEEERNE LKKSVDQLKQ  60
   61 QIATLKEANE KLETDLEKVE NVSPHFNETA SMMSGVTRQM NNRTSHKMSP TSSIIGIPED 120
  121 GELSGNQSTI LPIVTKQRDR FRSRNMDLEK QLRQGNSEKG KLKLEISKLK GDNTKLYERI 180
  181 RYLQSYNNNN APVNQSTERI DVESQYSRVY DESLHPMANF RQNELNHYKN KKLSALEKLF 240
  241 SSFAKVILQN KMTRMVFLFY CIGLHGLVFM MSMYVINISG YMTPEVGIVQ SAKSSSNLNG 300
  301 GLGGAEKVAA GVGSVHGINR 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [442-609]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPHFNETASM MSGVTRQMNN RTSHKMSPTS SIIGIPEDGE LSGNQSTILP IVTKQRDRFR  60
   61 SRNMDLEKQL RQGNSEKGKL KLEISKLKGD NTKLYERIRY LQSYNNNNAP VNQSTERIDV 120
  121 ESQYSRVYDE SLHPMANFRQ NELNHYKNKK LSALEKLFSS FAKVILQN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 4.522879
Match: 2iw5A
Description: No description for 2iw5A was found.

Predicted Domain #4
Region A:
Residues: [610-679]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KMTRMVFLFY CIGLHGLVFM MSMYVINISG YMTPEVGIVQ SAKSSSNLNG GLGGAEKVAA  60
   61 GVGSVHGINR 

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle