YRC Public Data Repository - Protein Structure Prediction

Protein:	AVT3
Organism:	Saccharomyces cerevisiae
Length:	692 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AVT3.

Description	E-value	Query Range	Subject Range
AVT3_YEAST - Vacuolar amino acid transporter 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=AVT3 P... AVT3 - Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seve...	0.0	[1..692]	[1..692]
SPAC3H1.09c - vacuolar amino acid transporter AVT3_SCHPO - Vacuolar amino acid transporter 3 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=avt3 PE=...	3.0E-92	[79..688]	[72..656]
gi\|215485276, gi... - gi\|215485276\|ref\|YP_002327707.1\| aromatic amino acid transporter [Escherichia coli O127:H6 str. E234... gi\|170079749, gi... - gi\|170079749\|ref\|YP_001729069.1\| aromatic amino acid transporter [Escherichia coli str. K-12 substr.... gi\|218359460, gi... - gi\|218552692\|ref\|YP_002385605.1\| aromatic amino acid transporter [Escherichia coli IAI1], gi\|2183594... gi\|218547567, gi... - gi\|218547567\|ref\|YP_002381358.1\| aromatic amino acid transporter [Escherichia fergusonii ATCC 35469]... EG10084 - aromatic amino acid transporter / General aromatic amino acid transport permease gi\|85674334, gi\|... - gi\|89106993\|ref\|AP_000773.1\| aromatic amino acid transporter [Escherichia coli str. K-12 substr. W31... gi\|75258895 - gi\|75258895\|ref\|ZP_00730285.1\| COG1113: Gamma-aminobutyrate permease and related permeases [Escheric... gi\|75233839 - gi\|75233839\|ref\|ZP_00718309.1\| COG1113: Gamma-aminobutyrate permease and related permeases [Escheric... gi\|75230526 - gi\|75230526\|ref\|ZP_00717007.1\| COG1113: Gamma-aminobutyrate permease and related permeases [Escheric... gi\|75208424 - gi\|75208424\|ref\|ZP_00708756.1\| COG1113: Gamma-aminobutyrate permease and related permeases [Escheric... gi\|75194327 - gi\|75194327\|ref\|ZP_00704397.1\| COG1113: Gamma-aminobutyrate permease and related permeases [Escheric... EG10084 - aromatic amino acid transporter / General aromatic amino acid transport permease AROP_ECOLI - Aromatic amino acid transport protein aroP (General aromatic amino acid permease) - Escherichia coli gi\|238860015, gi... - gi\|238899511\|ref\|YP_002925307.1\| aromatic amino acid transporter [Escherichia coli BW2952], gi\|23886... gi\|242375946, gi... - gi\|251783673\|ref\|YP_002997977.1\| hypothetical protein B21_00110 [Escherichia coli BL21], gi\|24237594... gi\|253972133, gi... - gi\|254160232\|ref\|YP_003043340.1\| aromatic amino acid transporter [Escherichia coli B str. REL606], g... gi\|254287035, gi... - gi\|254287035\|ref\|YP_003052783.1\| aromatic amino acid transporter [Escherichia coli BL21(DE3)], gi\|25...	1.0E-79	[287..683]	[5..421]
gi\|1778491 - gi\|1778491\|gb\|AAB40774.1\| phenylalanine-specific permease [Escherichia coli]	1.0E-79	[282..682]	[20..440]
gi\|68470470, gi\|... - gi\|68470731\|ref\|XP_720611.1\| N-acetylglucosamine-inducible general amino acid permease [Candida albi... gi\|18568390 - gi\|18568390\|gb\|AAL76065.1\| Gap1 protein [Candida albicans] gi\|238882678 - gi\|238882678\|gb\|EEQ46316.1\| general amino-acid permease GAP1 [Candida albicans WO-1]	1.0E-79	[230..688]	[4..499]
gi\|13360072, gi\|... - gi\|15829868\|ref\|NP_308641.1\| phenylalanine transporter [Escherichia coli O157:H7 str. Sakai], gi\|133... gi\|209777706, gi... - pir\|\|A85556 phenylalanine-specific transport system [imported] - Escherichia coli (strain O157:H7, s... gi\|208726466, gi... - gi\|208806665\|ref\|ZP_03249002.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. EC420... gi\|254791741, gi... - gi\|254791741\|ref\|YP_003076578.1\| phenylalanine transporter [Escherichia coli O157:H7 str. TW14359], ... gi\|217326443, gi... - gi\|217326443\|ref\|ZP_03442527.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. TW145... gi\|12513461, gi\|... - gi\|15800289\|ref\|NP_286301.1\| phenylalanine transporter [Escherichia coli O157:H7 EDL933], gi\|1251346... gi\|13360072, gi\|... - gi\|15829868\|ref\|NP_308641.1\| phenylalanine-specific transport system [Escherichia coli O157:H7], gi\|... gi\|168754668, gi... - gi\|189357991\|gb\|EDU76410.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. EC4401], ... gi\|189369115, gi... - gi\|189369115\|gb\|EDU87531.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. EC4501], ... gi\|189360870, gi... - gi\|189360870\|gb\|EDU79289.1\| phenylalanine-specific permease [Escherichia coli O157:H7 str. EC4486], ... gi\|195936121 - gi\|195936121\|ref\|ZP_03081503.1\| phenylalanine transporter [Escherichia coli O157:H7 str. EC4024]	3.0E-79	[282..682]	[8..428]

Back

Predicted Domain #1

Region A:
Residues: [1-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNGKEVSSGS GRTQSNNNKK NNNGGSTGIS HASGSPLTDG NGGNSNGNSR SRSRSRKSSG  60
   61 TTGGLLKKPP LLVNNEAVHA SVPDASHTSC NNGTLEVSIN NPEPHVVDAV ARHLIRNPSN 120
  121 SLQLQGGDIT RDLYKWTNDH PSSPSQYQYP SQPALSTSIP SQAPSFSNRK RSMSFSAASI 180
  181 ASSSHLNNNS EANGNPLAAI GLAPAPMTHE EIRAPGGFRR SFIIQKRRKH NVDAPIPNFF 240
  241 TRNFIEFLTL YGHFAGEDLS EEEEEEEETE EEPEEEALET ES

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [283-692]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TQLVSREHGR HPHKSSTVKA VLLLLKSFVG TGVLFLPKAF HNGGWGFSAL CLLSCALISY  60
   61 GCFVSLITTK DKVGVDGYGD MGRILYGPKM KFAILSSIAL SQIGFSAAYT VFTATNLQVF 120
  121 SENFFHLKPG SISLATYIFA QVLIFVPLSL TRNIAKLSGT ALIADLFILL GLVYVYVYSI 180
  181 YYIAVNGVAS DTMLMFNKAD WSLFIGTAIF TFEGIGLLIP IQESMKHPKH FRPSLSAVMC 240
  241 IVAVIFISCG LLCYAAFGSD VKTVVLLNFP QDTSYTLTVQ LLYALAILLS TPLQLFPAIR 300
  301 ILENWTFPSN ASGKYNPKVK WLKNYFRCAI VVLTSILAWV GANDLDKFVS LVGSFACIPL 360
  361 IYIYPPLLHY KASILSGTSR ARLLLDLIVI VFGVAVMAYT SWQTIKMWSQ

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	145.69897
Match:	PF01490
Description:	Transmembrane amino acid transporter protein

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [293-692]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HPHKSSTVKA VLLLLKSFVG TGVLFLPKAF HNGGWGFSAL CLLSCALISY GCFVSLITTK  60
   61 DKVGVDGYGD MGRILYGPKM KFAILSSIAL SQIGFSAAYT VFTATNLQVF SENFFHLKPG 120
  121 SISLATYIFA QVLIFVPLSL TRNIAKLSGT ALIADLFILL GLVYVYVYSI YYIAVNGVAS 180
  181 DTMLMFNKAD WSLFIGTAIF TFEGIGLLIP IQESMKHPKH FRPSLSAVMC IVAVIFISCG 240
  241 LLCYAAFGSD VKTVVLLNFP QDTSYTLTVQ LLYALAILLS TPLQLFPAIR ILENWTFPSN 300
  301 ASGKYNPKVK WLKNYFRCAI VVLTSILAWV GANDLDKFVS LVGSFACIPL IYIYPPLLHY 360
  361 KASILSGTSR ARLLLDLIVI VFGVAVMAYT SWQTIKMWSQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.522879
Match:	2a65A
Description:	Crystal structure of LEUTAA, a bacterial homolog of Na+/Cl--dependent neurotransmitter transporters
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits