YRC Public Data Repository - Protein Structure Prediction

Protein:	LAP4
Organism:	Saccharomyces cerevisiae
Length:	514 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LAP4.

Description	E-value	Query Range	Subject Range
DNPEP - aspartyl aminopeptidase	0.0	[45..507]	[10..468]
LAP4 - Vacuolar aminopeptidase yscI; zinc metalloproteinase that belongs to the peptidase family M18; often... AMPL_YEAST - Vacuolar aminopeptidase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APE1 PE=1 SV=2 gi\|151941700 - gi\|151941700\|gb\|EDN60062.1\| vacuolar aminopeptidase ysc1 [Saccharomyces cerevisiae YJM789]	0.0	[1..514]	[1..514]
gi\|34905926, gi\|... - gi\|34905926\|ref\|NP_914310.1\| aspartyl aminopeptidase-like protein [Oryza sativa (japonica cultivar-g...	0.0	[51..510]	[63..521]
gi\|7413533, gi\|1... - gi\|9758446\|dbj\|BAB08975.1\| aspartyl aminopeptidase [Arabidopsis thaliana], gi\|7413533\|emb\|CAB86013.1...	0.0	[51..510]	[65..521]
DNPEP_SCHPO - Aspartyl aminopeptidase 1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=aap1 PE=1 SV=1 SPAC4F10.02 - aminopeptidase	0.0	[50..510]	[6..462]
gi\|16226017, gi\|... - gi\|16226017\|gb\|AAL16055.1\|AF420304_1 aspartyl aminopeptidase [Coccidioides immitis], gi\|16225946\|gb\|...	0.0	[48..507]	[3..488]

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Predicted Domain #1

Region A:
Residues: [1-514]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEEQREILEQ LKKTLQMLTV EPSKNNQIAN EEKEKKENEN SWCILEHNYE DIAQEFIDFI  60
   61 YKNPTTYHVV SFFAELLDKH NFKYLSEKSN WQDSIGEDGG KFYTIRNGTN LSAFILGKNW 120
  121 RAEKGVGVIG SHVDALTVKL KPVSFKDTAE GYGRIAVAPY GGTLNELWLD RDLGIGGRLL 180
  181 YKKKGTNEIK SALVDSTPLP VCRIPSLAPH FGKPAEGPFD KEDQTIPVIG FPTPDEEGNE 240
  241 PPTDDEKKSP LFGKHCIHLL RYVAKLAGVE VSELIQMDLD LFDVQKGTIG GIGKHFLFAP 300
  301 RLDDRLCSFA AMIALICYAK DVNTEESDLF STVTLYDNEE IGSLTRQGAK GGLLESVVER 360
  361 SSSAFTKKPV DLHTVWANSI ILSADVNHLY NPNFPEVYLK NHFPVPNVGI TLSLDPNGHM 420
  421 ATDVVGTALV EELARRNGDK VQYFQIKNNS RSGGTIGPSL ASQTGARTID LGIAQLSMHS 480
  481 IRAATGSKDV GLGVKFFNGF FKHWRSVYDE FGEL

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	262.744727
Match:	PF02127
Description:	Aminopeptidase I zinc metalloprotease (M18)

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits