YRC Public Data Repository - Protein Structure Prediction

Protein:	MTC2
Organism:	Saccharomyces cerevisiae
Length:	357 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTC2.

Description	E-value	Query Range	Subject Range
gi\|7442961 - pir\|\|B71126 hypothetical protein PH0776 - Pyrococcus horikoshii gi\|14590644, gi\|... - gi\|3257185\|dbj\|BAA29868.1\| 314aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14590644\|...	4.0E-67	[1..330]	[19..314]
gi\|7442969, gi\|5... - pir\|\|C75037 methanol dehydrogenase regulatory protein (moxr-3) PAB0848 - Pyrococcus abyssi (strain O... gi\|14521486, gi\|... - gi\|5458705\|emb\|CAB50192.1\| moxR-3 methanol dehydrogenase regulatory protein [Pyrococcus abyssi GE5],...	5.0E-66	[1..330]	[19..314]
gi\|18976889, gi\|... - gi\|18976889\|ref\|NP_578246.1\| methanol dehydrogenase regulatory protein [Pyrococcus furiosus DSM 3638...	3.0E-65	[8..330]	[23..314]
MTC2_YEAS7 - Maintenance of telomere capping protein 2 OS=Saccharomyces cerevisiae (strain YJM789) GN=MTC2 PE=3 S... MTC2_YEAST - Maintenance of telomere capping protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G... MTC2 - Protein of unknown function; mtc2 is synthetically sick with cdc13-1	2.0E-64	[1..357]	[1..357]
gi\|7799213, gi\|2... - gi\|7799213\|emb\|CAB90929.1\| putative regulatory protein [Streptomyces coelicolor A3(2)], gi\|21221461\|...	2.0E-64	[1..328]	[33..329]
gi\|215405743 - gi\|215405743\|ref\|ZP_03417924.1\| methanol dehydrogenase transcriptional regulatory protein moxR2 [Myc... gi\|224775217, gi... - gi\|224992102\|ref\|YP_002646791.1\| putative methanol dehydrogenase transcriptional regulatory protein ... gi\|218755472 - gi\|218755472\|ref\|ZP_03534268.1\| methanol dehydrogenase transcriptional regulatory protein moxR2 [Myc... gi\|121495254, gi... - gi\|121639606\|ref\|YP_979830.1\| putative methanol dehydrogenase transcriptional regulatory protein mox... gi\|215448029 - gi\|215448029\|ref\|ZP_03434781.1\| methanol dehydrogenase transcriptional regulatory protein moxR2 [Myc... gi\|215413618 - gi\|215413618\|ref\|ZP_03422286.1\| methanol dehydrogenase transcriptional regulatory protein moxR2 [Myc... gi\|194542240, gi... - gi\|254233189\|ref\|ZP_04926515.1\| methanol dehydrogenase transcriptional regulatory protein moxR2 [Myc... gi\|148824896, gi... - gi\|148824896\|ref\|YP_001289650.1\| methanol dehydrogenase transcriptional regulatory protein moxR2 [My... gi\|13883670, gi\|... - gi\|15843310\|ref\|NP_338347.1\| magnesium chelatase, putative [Mycobacterium tuberculosis CDC1551], gi\|... gi\|134151749, gi... - gi\|254366237\|ref\|ZP_04982281.1\| methanol dehydrogenase transcriptional regulatory protein moxR2 [Myc... gi\|148507707, gi... - gi\|148663555\|ref\|YP_001285078.1\| putative methanol dehydrogenase transcriptional regulatory protein ... gi\|254552804 - gi\|254552804\|ref\|ZP_05143251.1\| methanol dehydrogenase transcriptional regulator moxR2 [Mycobacteriu... gi\|253800736, gi... - gi\|253800736\|ref\|YP_003033737.1\| methanol dehydrogenase transcriptional regulator moxR2 [Mycobacteri... gi\|7442964 - pir\|\|E70792 probable regulatory protein - Mycobacterium tuberculosis (strain H37RV) gi\|255095000 - gi\|255095000\|ref\|ZP_05324478.1\| putative methanol dehydrogenase transcriptional regulatory protein [... gi\|254818085 - gi\|254818085\|ref\|ZP_05223086.1\| putative methanol dehydrogenase transcriptional regulatory protein [... gi\|2960116, gi\|1... - gi\|2960116\|emb\|CAA18014.1\| PROBABLE METHANOL DEHYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN MOXR2 ... gi\|31620461, gi\|... - gi\|31794863\|ref\|NP_857356.1\| putative methanol dehydrogenase transcriptional regulatory protein MOXR...	5.0E-63	[1..328]	[64..358]
gi\|4981679, gi\|1... - gi\|4981679\|gb\|AAD36208.1\|AE001771_1 moxR protein, putative [Thermotoga maritima MSB8], gi\|15643889\|r... gi\|7442971 - pir\|\|H72289 hypothetical protein TM1132 - Thermotoga maritima (strain MSB8)	7.0E-63	[4..328]	[14..305]
gi\|9657565, gi\|1... - gi\|9657565\|gb\|AAF96088.1\| MoxR-related protein [Vibrio cholerae O1 biovar eltor str. N16961], gi\|156... gi\|11277522 - pir\|\|H82493 MoxR-related protein VCA0175 [imported] - Vibrio cholerae (strain N16961 serogroup O1) gi\|229510542, gi... - gi\|229510542\|ref\|ZP_04400022.1\| hypothetical protein VCE_001950 [Vibrio cholerae B33], gi\|229352987\|... gi\|75830957, gi\|... - gi\|75830957\|ref\|ZP_00760226.1\| COG0714: MoxR-like ATPases [Vibrio cholerae MO10], gi\|254850441\|ref\|Z... gi\|229605137, gi... - gi\|229605137\|ref\|YP_002875841.1\| hypothetical protein VCD_000075 [Vibrio cholerae MJ-1236], gi\|22937... gi\|229345362, gi... - gi\|229517326\|ref\|ZP_04406771.1\| hypothetical protein VCC_001347 [Vibrio cholerae RC9], gi\|229345362\|...	8.0E-63	[1..313]	[18..308]
gi\|25298526 - pir\|\|C83741 hypothetical protein BH0731 [imported] - Bacillus halodurans (strain C-125) gi\|10173345, gi\|... - gi\|15613294\|ref\|NP_241597.1\| hypothetical protein BH0731 [Bacillus halodurans C-125], gi\|10173345\|db...	8.0E-63	[3..328]	[16..308]

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Predicted Domain #1

Region A:
Residues: [1-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGDHNLPDFQ TCLKFSVTAK KSFLCMYRDS VSKEKLASSM PSTCDIQLKR AINDAYPGGG  60
   61 IKVTVLNSTT ASLDSLATTH VKEFEIVIIP DINSLLQPDQ AKLVKIMRDC TVAIEKAQST 120
  121 RIFIGVVHWN NPVQPSGAAK DGDEAGKPAP KTRIFLPTSF RMGAWLKHKF WFACAPPYLD 180
  181 FESSTESSIN TRANNSIGMA EEEKQEPESK RSIILNEE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.69897
Match:	1g8pA_
Description:	ATPase subunit of magnesium chelatase, BchI
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [219-357]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANLNDVFVGS TVRRYILDIM VHLRTHRLTY NAKAGGVYTN SLDDVVLLSR LIGLHSGKMF  60
   61 VSPSHVKEAS RWYFPMHLEL VQRSSMDSSL LYGSDPNLVD EMLEKLAKIK CEEVNEFENP 120
  121 LFLESLVVKN VLSKVVPPV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	36.69897
Match:	1g8pA_
Description:	ATPase subunit of magnesium chelatase, BchI
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits