YRC Public Data Repository - Protein Structure Prediction

Protein:	HOT13
Organism:	Saccharomyces cerevisiae
Length:	116 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HOT13.

Description	E-value	Query Range	Subject Range
HOT13_YEAST - Helper of Tim protein 13 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HOT13 PE=1 SV=1 gi\|190409746 - gi\|190409746\|gb\|EDV13011.1\| assembly factor for the Translocase of the Inner Membrane complexes [Sac... HOT13 - Mitochondrial intermembrane space protein, first component of a pathway mediating assembly of small ...	5.0E-40	[1..116]	[1..116]
YEMC_SCHPO - Uncharacterized protein C29B12.12 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC29B1... SPAC29B12.12 - helper of TIM	6.0E-31	[4..110]	[10..112]
gi\|15923727, gi\|... - gi\|15923727\|ref\|NP_371261.1\| hypothetical protein SAV0737 [Staphylococcus aureus subsp. aureus Mu50]... gi\|15926414, gi\|... - gi\|15926414\|ref\|NP_373947.1\| hypothetical protein SA0692 [Staphylococcus aureus subsp. aureus N315],... gi\|49482994, gi\|... - gi\|49482994\|ref\|YP_040218.1\| hypothetical protein SAR0791 [Staphylococcus aureus subsp. aureus MRSA2... gi\|49244052, gi\|... - gi\|49485609\|ref\|YP_042830.1\| hypothetical protein SAS0702 [Staphylococcus aureus subsp. aureus MSSA4... gi\|156721200, gi... - gi\|156979065\|ref\|YP_001441324.1\| hypothetical protein SAHV_0734 [Staphylococcus aureus subsp. aureus... gi\|25353254 - pir\|\|B89846 conserved hypothetical protein SA0692 [imported] - Staphylococcus aureus (strain N315) gi\|150373718, gi... - gi\|151220918\|ref\|YP_001331740.1\| hypothetical protein NWMN_0706 [Staphylococcus aureus subsp. aureus... gi\|21282428, gi\|... - gi\|21282428\|ref\|NP_645516.1\| hypothetical protein MW0699 [Staphylococcus aureus subsp. aureus MW2], ... gi\|221140824 - gi\|221140824\|ref\|ZP_03565317.1\| hypothetical protein SauraJ_04198 [Staphylococcus aureus subsp. aure... gi\|227246435, gi... - gi\|227557171\|ref\|ZP_03987218.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|227899263, gi... - gi\|227899263\|ref\|ZP_04017068.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|251802813, gi... - gi\|251813707\|ref\|ZP_04828180.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|253315830 - gi\|253315830\|ref\|ZP_04839043.1\| hypothetical protein SauraC_06725 [Staphylococcus aureus subsp. aure... gi\|253731365, gi... - gi\|253731365\|ref\|ZP_04865530.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|253732815, gi... - gi\|253732815\|ref\|ZP_04866980.1\| CHY zinc finger family protein [Staphylococcus aureus subsp. aureus ... gi\|255005528 - gi\|255005528\|ref\|ZP_05144129.2\| hypothetical protein SauraM_03635 [Staphylococcus aureus subsp. aure... gi\|90582497, gi\|... - gi\|90582497\|ref\|ZP_01238260.1\| CHY zinc finger [Staphylococcus aureus subsp. aureus JH1], gi\|9042828... gi\|57285761, gi\|... - gi\|57651575\|ref\|YP_185674.1\| hypothetical protein SACOL0800 [Staphylococcus aureus subsp. aureus COL... gi\|90585254, gi\|... - gi\|90585254\|ref\|ZP_01240964.1\| CHY zinc finger [Staphylococcus aureus subsp. aureus JH9], gi\|9043098... gi\|88194515, gi\|... - gi\|88194515\|ref\|YP_499310.1\| hypothetical protein SAOUHSC_00751 [Staphylococcus aureus subsp. aureus... gi\|82655972, gi\|... - gi\|82750441\|ref\|YP_416182.1\| hypothetical protein SAB0689c [Staphylococcus aureus RF122], gi\|8265597... gi\|221137636 - gi\|221137636\|ref\|ZP_03562442.1\| hypothetical protein SauraJK_03148 [Staphylococcus aureus subsp. aur...	5.0E-29	[6..109]	[4..103]
gi\|25353253 - pir\|\|D95166 conserved hypothetical protein SP1428 [imported] - Streptococcus pneumoniae (strain TIGR... gi\|14972917, gi\|... - gi\|15901281\|ref\|NP_345885.1\| hypothetical protein SP_1428 [Streptococcus pneumoniae TIGR4], gi\|14972... gi\|148990557, gi... - gi\|148990557\|ref\|ZP_01821683.1\| hypothetical protein CGSSp6BS73_01188 [Streptococcus pneumoniae SP6-...	2.0E-27	[8..109]	[6..103]
gi\|21909686, gi\|... - gi\|21909686\|ref\|NP_663954.1\| hypothetical protein SpyM3_0150 [Streptococcus pyogenes MGAS315], gi\|21... gi\|19747458, gi\|... - gi\|19747458\|gb\|AAL96989.1\| hypothetical protein spyM18_0191 [Streptococcus pyogenes MGAS8232], gi\|19... gi\|209539950, gi... - gi\|209558749\|ref\|YP_002285221.1\| hypothetical protein Spy49_0182 [Streptococcus pyogenes NZ131], gi\|... gi\|28895067, gi\|... - gi\|28895067\|ref\|NP_801417.1\| hypothetical protein SPs0155 [Streptococcus pyogenes SSI-1], gi\|2881031... gi\|139473040, gi... - gi\|139473040\|ref\|YP_001127755.1\| CHY zinc finger protein [Streptococcus pyogenes str. Manfredo], gi\|... gi\|71801935, gi\|... - gi\|71902840\|ref\|YP_279643.1\| zinc finger protein [Streptococcus pyogenes MGAS6180], gi\|71801935\|gb\|A... gi\|94989688, gi\|... - gi\|94989688\|ref\|YP_597788.1\| Zinc finger protein [Streptococcus pyogenes MGAS10270], gi\|94543196\|gb\|... gi\|94991684, gi\|... - gi\|94991684\|ref\|YP_599783.1\| Zinc finger protein [Streptococcus pyogenes MGAS2096], gi\|94545192\|gb\|A... gi\|94541317, gi\|... - gi\|94987809\|ref\|YP_595910.1\| zinc finger protein [Streptococcus pyogenes MGAS9429], gi\|94541317\|gb\|A...	1.0E-26	[4..108]	[2..99]
gi\|15674404, gi\|... - gi\|15674404\|ref\|NP_268578.1\| hypothetical protein SPy_0205 [Streptococcus pyogenes M1 GAS], gi\|13621... gi\|71909990, gi\|... - gi\|71909990\|ref\|YP_281540.1\| zinc finger protein [Streptococcus pyogenes MGAS5005], gi\|71852772\|gb\|A...	6.0E-26	[4..108]	[2..99]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-17	[18..96]	[13..86]

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Predicted Domain #1

Region A:
Residues: [1-116]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIETAIYGKT VDDQSRCVHW HLPKDVIAIR FKCCDKYYAC FECHQELSSH PLEKYDLLDD  60
   61 ANKHLIICGV CRHEMTFAEY YDYNSNLICP NCRSPFNPGC KLHYHLYFQN PPPAMC

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.494	b.55.1	PH domain-like
View	Download	0.371	a.3.1	Cytochrome c
View	Download	0.231	c.47.1	Thioredoxin-like
View	Download	0.212	a.26.1	4-helical cytokines

Predicted functions:

Term	Confidence	Notes
binding	2.27826637472119	bayes_pls_golite062009
protein binding	1.29668949042818	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: