YRC Public Data Repository - Protein Structure Prediction

Protein:	CAP1
Organism:	Saccharomyces cerevisiae
Length:	268 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CAP1.

Description	E-value	Query Range	Subject Range
CAZA1_CHICK - F-actin-capping protein subunit alpha-1 OS=Gallus gallus GN=CAPZA1 PE=1 SV=1	0.0	[1..263]	[8..282]
CAPZA1 - capping protein (actin filament) muscle Z-line, alpha 1 gi\|123979702, gi... - gi\|61355548\|gb\|AAX41151.1\| capping protein muscle Z-line alpha 1 [synthetic construct], gi\|60821852\|...	0.0	[1..263]	[8..282]
CAZA1_MOUSE - F-actin-capping protein subunit alpha-1 OS=Mus musculus GN=Capza1 PE=1 SV=4	0.0	[1..263]	[8..282]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	0.0	[1..263]	[6..280]
cpa-PA - The gene capping protein alpha is referred to in FlyBase by the symbol Dmel\cpa (CG10540, FBgn003457... gi\|195585280, gi... - gi\|195585280\|ref\|XP_002082417.1\| GD11558 [Drosophila simulans], gi\|194194426\|gb\|EDX08002.1\| GD11558 ... gi\|194135043, gi... - gi\|195346281\|ref\|XP_002039694.1\| GM15798 [Drosophila sechellia], gi\|194135043\|gb\|EDW56559.1\| GM15798... gi\|220954928, gi... - gi\|220954928\|gb\|ACL90007.1\| cpa-PA [synthetic construct], gi\|220945024\|gb\|ACL85055.1\| cpa-PA [synthe...	0.0	[1..264]	[6..283]
gi\|226575 - gi\|226575\|prf\|\|1602248A nuclear actin binding protein CAZA1_XENLA - F-actin-capping protein subunit alpha-1 (Fragment) OS=Xenopus laevis GN=capza1 PE=1 SV=1	0.0	[24..263]	[1..252]

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Predicted Domain #1

Region A:
Residues: [1-268]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSKFEEVI NKIINDSPPG ELREVYDDLI KITSENSKNT ILDAIENYNV QNCIPIEVNG  60
   61 NSVIISKYNK EGAKFFDPVN SVIFSVNHLE RKGLDIEPYE FTHAKIEKGQ LKELHDKLHE 120
  121 YLLQSFPGDV SFAVYPVPEE ISKISIIIVS TKYNPNNFWN GHWRSSYIYD LETRELSGQI 180
  181 STQVHYYEDG NVSFQSGKDI NQSNVDDVVC TIRDIETNFE NDLDLSFFDL NEKQFKALRR 240
  241 RLPVTRSKIN WGSAIGSYRL GKNAAEGK

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	172.0
Match:	PF01267
Description:	F-actin capping protein alpha subunit

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
actin binding	6.56144513012007	bayes_pls_golite062009
actin filament binding	5.39928513902709	bayes_pls_golite062009
cytoskeletal protein binding	5.10504476256679	bayes_pls_golite062009
binding	2.03345990933192	bayes_pls_golite062009
protein binding	1.31870344025745	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: