YRC Public Data Repository - Protein Structure Prediction

Protein:	DID4
Organism:	Saccharomyces cerevisiae
Length:	232 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for DID4.

Description	E-value	Query Range	Subject Range
DID4_YEAST - DOA4-independent degradation protein 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=D... DID4 - Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins int...	1.0E-35	[1..232]	[1..232]
VPS2A_ARATH - Vacuolar protein sorting-associated protein 2 homolog 1 OS=Arabidopsis thaliana GN=VPS2.1 PE=1 SV=2	8.0E-32	[3..230]	[1..224]
gi\|24059999, gi\|... - gi\|34900542\|ref\|NP_911617.1\| breast adenocarcinoma marker-like [Oryza sativa (japonica cultivar-grou...	3.0E-31	[4..230]	[1..224]
gi\|46438467, gi\|... - gi\|68478326\|ref\|XP_716784.1\| hypothetical protein CaO19.945 [Candida albicans SC5314], gi\|68478205\|r... gi\|238882456 - gi\|238882456\|gb\|EEQ46094.1\| DOA4-independent degradation protein 4 [Candida albicans WO-1] orf19.945, orf19... - VPS2 CGDID:CAL0003689 Assembly 19, Contig19-10080 (77819, 78526) CDS, translated using codon table 1...	3.0E-31	[1..230]	[1..235]
gi\|44980889 - gi\|44980889\|gb\|AAS50772.1\| ABR002Cp [Ashbya gossypii ATCC 10895] gi\|45185231, gi\|... - gi\|45185231\|ref\|NP_982948.1\| ABR002Cp [Ashbya gossypii ATCC 10895], gi\|44980889\|gb\|AAS50772.1\| ABR00...	4.0E-31	[1..230]	[1..233]
gi\|46116540, gi\|... - gi\|46116540\|ref\|XP_384288.1\| hypothetical protein FG04112.1 [Gibberella zeae PH-1], gi\|42549471\|gb\|E...	8.0E-31	[1..230]	[1..228]
CE06928 - WBGene00016497 status:Predicted TR:Q22916 protein_id:AAC25860.1	1.0E-30	[1..223]	[49..262]
gi\|4680707 - gi\|4680707\|gb\|AAD27743.1\|AF132968_1 CGI-34 protein [Homo sapiens]	5.0E-30	[4..207]	[1..209]

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Predicted Domain #1

Region A:
Residues: [1-232]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLFEWVFGK NVTPQERLKK NQRALERTQR ELEREKRKLE LQDKKLVSEI KKSAKNGQVA  60
   61 AAKVQAKDLV RTRNYIQKFD NMKAQLQAIS LRIQAVRSSD QMTRSMSEAT GLLAGMNRTM 120
  121 NLPQLQRISM EFEKQSDLMG QRQEFMDEAI DNVMGDEVDE DEEADEIVNK VLDEIGVDLN 180
  181 SQLQSTPQNL VSNAPIAETA MGIPEPIGAG SEFHGNPDDD LQARLNTLKK QT

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	35.040959
Match:	PF03357.7
Description:	No description for PF03357.7 was found.

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits