YRC Public Data Repository - Protein Structure Prediction

Protein:	YJR149W
Organism:	Saccharomyces cerevisiae
Length:	404 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJR149W.

Description	E-value	Query Range	Subject Range
gi\|25284006 - pir\|\|D97232 IMP dehydrogenase (EC 1.1.1.205) [similarity] - Clostridium acetobutylicum gi\|15025734, gi\|... - gi\|15895958\|ref\|NP_349307.1\| inositol-5-monophosphate dehydrogenase [Clostridium acetobutylicum ATCC...	6.0E-81	[6..401]	[8..466]
IMDH_BACSU - Inosine-5'-monophosphate dehydrogenase OS=Bacillus subtilis (strain 168) GN=guaB PE=1 SV=2 gi\|221312140 - gi\|221312140\|ref\|ZP_03593945.1\| inositol-5'-monophosphate dehydrogenase [Bacillus subtilis subsp. su... gi\|221317073 - gi\|221317073\|ref\|ZP_03598367.1\| inositol-5'-monophosphate dehydrogenase [Bacillus subtilis subsp. su... IMDH_BACSU - Inosine-5'-monophosphate dehydrogenase OS=Bacillus subtilis GN=guaB PE=1 SV=2 gi\|221321336 - gi\|221321336\|ref\|ZP_03602630.1\| inositol-5'-monophosphate dehydrogenase [Bacillus subtilis subsp. su...	2.0E-80	[5..401]	[9..470]
IMDH_BACHD - Inosine-5'-monophosphate dehydrogenase OS=Bacillus halodurans GN=guaB PE=3 SV=1 IMDH_BACHD - Inosine-5'-monophosphate dehydrogenase OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18197 / FER...	6.0E-80	[5..401]	[9..468]
IMDH_BACSU - Inosine-5'-monophosphate dehydrogenase OS=Bacillus subtilis (strain 168) GN=guaB PE=1 SV=2 gi\|221312140 - gi\|221312140\|ref\|ZP_03593945.1\| inositol-5'-monophosphate dehydrogenase [Bacillus subtilis subsp. su... gi\|221317073 - gi\|221317073\|ref\|ZP_03598367.1\| inositol-5'-monophosphate dehydrogenase [Bacillus subtilis subsp. su... IMDH_BACSU - Inosine-5'-monophosphate dehydrogenase OS=Bacillus subtilis GN=guaB PE=1 SV=2 gi\|221321336 - gi\|221321336\|ref\|ZP_03602630.1\| inositol-5'-monophosphate dehydrogenase [Bacillus subtilis subsp. su...	4.0E-79	[5..401]	[9..470]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	5.0E-78	[5..401]	[9..470]
gi\|6705995 - gi\|6705995\|dbj\|BAA89464.1\| IMPDH [Bacillus cereus]	6.0E-77	[5..401]	[9..470]
IMDH_AQUAE - Inosine-5'-monophosphate dehydrogenase OS=Aquifex aeolicus GN=guaB PE=3 SV=1 IMDH_AQUAE - Inosine-5'-monophosphate dehydrogenase OS=Aquifex aeolicus (strain VF5) GN=guaB PE=3 SV=1	9.0E-77	[3..401]	[8..472]
gi\|147736109, gi... - gi\|148270565\|ref\|YP_001245025.1\| inosine-5'-monophosphate dehydrogenase [Thermotoga petrophila RKU-1... gi\|254483680, gi... - gi\|254483680\|ref\|ZP_05096897.1\| inosine-5'-monophosphate dehydrogenase [Marinitoga piezophila KA3], ... gi\|4981907, gi\|1... - gi\|4981907\|gb\|AAD36418.1\|AE001789_3 inosine-5'-monophosphate dehydrogenase [Thermotoga maritima MSB8... gi\|7431403 - pir\|\|C72264 IMP dehydrogenase (EC 1.1.1.205) - Thermotoga maritima (strain MSB8)	1.0E-76	[5..401]	[3..463]
IMDH_HELPY - Inosine-5'-monophosphate dehydrogenase OS=Helicobacter pylori (strain ATCC 700392 / 26695) GN=guaB P... IMDH_HELPY - Inosine-5'-monophosphate dehydrogenase OS=Helicobacter pylori GN=guaB PE=3 SV=1	6.0E-76	[1..401]	[1..464]
gi\|7427686 - pir\|\|H71890 IMP dehydrogenase (EC 1.1.1.205) - Helicobacter pylori (strain J99) IMDH_HELPJ - Inosine-5'-monophosphate dehydrogenase OS=Helicobacter pylori (strain J99 / ATCC 700824) GN=guaB PE=...	1.0E-75	[1..401]	[1..464]

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Predicted Domain #1

Region A:
Residues: [1-404]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYFLNQLIFQ DVSVMSVDKR EDMSRSFQKC LNLRYPIIQA PMAGVTTIEM AAKACIAGAI  60
   61 ASLPLSHLDF RKVNDIEKLK LMVSQFRDQV ADESLEGNLN LNFFCHDIVD KPTDLQTANW 120
  121 AKLYRKSMNV PIDMNEIKFD NGNVSFKAFE KENALQDFFQ YLSDGFRPKI ISFHFGHPSK 180
  181 STIEYLQKIG ILIFVTATSV REVRLLARLG INGIVCQGYE AGGHRGNFLV NDPKDDENLS 240
  241 TVQLVKRTVD ELAEMKNKGL IHATPFVIAA GGIMDSKDIS YMLSQQADAV QVGTAFLGCS 300
  301 ESNASKNFSS PFTRETTTKM VNIISGKPAR TISTPFIEKV IANFQGEELP PYGYMYSAFK 360
  361 QVRKKYPELA NFILAGQGFQ NVQSGITTDK KIETMGARLK IVGK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	70.522879
Match:	1jr1A_
Description:	Inosine monophosphate dehydrogenase (IMPDH); Type II inosine monophosphate dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits