YRC Public Data Repository - Protein Structure Prediction

Protein:	YJR107W
Organism:	Saccharomyces cerevisiae
Length:	328 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJR107W.

Description	E-value	Query Range	Subject Range
YJR107W - Putative protein of unknown function; has sequence or structural similarity to lipases	3.0E-80	[1..328]	[1..328]
gi\|7801378, gi\|4... - gi\|7801378\|emb\|CAB91111.1\| triacylglycerol lipase [Yarrowia lipolytica], gi\|49646147\|emb\|CAG84220.1\|... gi\|50545489, gi\|... - gi\|50545489\|ref\|XP_500282.1\| YALI0A20350p [Yarrowia lipolytica], gi\|49646147\|emb\|CAG84220.1\| YlLIP2 ...	4.0E-56	[3..325]	[34..332]
LIP_THELA - Lipase OS=Thermomyces lanuginosus GN=LIP PE=1 SV=1	4.0E-54	[12..326]	[24..291]
PLA16_ARATH - Phospholipase A1-Igamma2, chloroplastic OS=Arabidopsis thaliana GN=At2g30550 PE=1 SV=2	1.0E-52	[11..315]	[120..464]
gi\|11124698 - gi\|11124698\|emb\|CAC15040.1\| triacylglycerol lipase [Candida ernobii]	2.0E-52	[8..325]	[25..327]

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Predicted Domain #1

Region A:
Residues: [1-328]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPVVHCSSNL PITLYIYERL VYFIKASSIS SCISDNLLLV NKTFNDGGCP PHINFCNDEI  60
   61 INPTAPQTVV ELVLNAKKGE LGSGYLAVDH GKKVVILAFR GSTTRQDWFS DFEIYPVNYS 120
  121 PLCVKEYRKL IEEGKIRECE GCKMHRGFLR FTETLGMDVF KKMESILESF PEYRIVVTGH 180
  181 SLGAALASLA GIELKIRGFD PLVLTFATPK IFNSEMKQWV DELFETDAIE KESILKDEIQ 240
  241 FRKGYFRVVH TGDYIPMVPP FYHPAGLEMF INKVGLPQNA EDIEYRGKNN RLTLKDGFRE 300
  301 GMSGLVEDWL HVYEHRAYFI DVVGCSGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	251.68867
Match:	1dt3A_
Description:	Triacylglycerol lipase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.41921458445725	bayes_pls_golite062009
catalytic activity	0.853693238072967	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.642148959457837	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: