YRC Public Data Repository - Protein Structure Prediction

Protein:	YJR096W
Organism:	Saccharomyces cerevisiae
Length:	282 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YJR096W.

Description	E-value	Query Range	Subject Range
AKR1B10 - aldo-keto reductase family 1, member B10 (aldose reductase) gi\|157927952, gi... - gi\|60656339\|gb\|AAX32733.1\| aldo-keto reductase family 1 member B10 [synthetic construct], gi\|6065633...	0.0	[2..273]	[1..297]
gi\|14330324, gi\|... - gi\|45382879\|ref\|NP_989960.1\| aldo-keto reductase family 1, member B10 [Gallus gallus], gi\|14330324\|e...	0.0	[1..278]	[1..303]
ALDR_RAT - Aldose reductase OS=Rattus norvegicus GN=Akr1b1 PE=1 SV=3	0.0	[2..274]	[1..298]
DHB5_MOUSE - Estradiol 17 beta-dehydrogenase 5 OS=Mus musculus GN=Akr1c6 PE=1 SV=1	0.0	[3..282]	[5..315]
gi\|15208400 - gi\|15208400\|dbj\|BAB63207.1\| 3(20)alpha-hydroxysteroid/dihydrodiol/indanol dehydrogenase [Macaca fusc... AK1C1_MACFU - Aldo-keto reductase family 1 member C1 homolog OS=Macaca fuscata fuscata GN=AKR1C1 PE=2 SV=1 gi\|109088079, gi... - gi\|109088083\|ref\|XP_001103887.1\| PREDICTED: aldo-keto reductase family 1, member C1 isoform 5 [Macac...	0.0	[1..274]	[1..305]
ALDR_RABIT - Aldose reductase OS=Oryctolagus cuniculus GN=AKR1B1 PE=2 SV=3	0.0	[2..274]	[1..298]
AK1C1_MACFA - Aldo-keto reductase family 1 member C1 homolog OS=Macaca fascicularis GN=AKR1C1 PE=1 SV=1	0.0	[1..274]	[1..305]

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Predicted Domain #1

Region A:
Residues: [1-196]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVPKFYKLSN GFKIPSIALG TYDIPRSQTA EIVYEGVKCG YRHFDTAVLY GNEKEVGDGI  60
   61 IKWLNEDPGN HKREEIFYTT KLWNSQNGYK RAKAAIRQCL NEVSGLQYID LLLIHSPLEG 120
  121 SKLRLETWRA MQEAVDEGLV KSIGVSNYGK KHIDELLNWP ELKHKPVVNQ IEISPWIMRQ 180
  181 ELADYCKSKG LVVEAF

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [230-253]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQHGYLPLPK TKTVKRLEGN LAAY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	525.0
Match:	1ihiA_
Description:	3-alpha-hydroxysteroid dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [197-229]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 APLCHGYKMT NPDLLKVCKE VDRNPGQVLI RWS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [254-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFELSDEQMK FLDHPDAYEP TDWECTDAP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	525.0
Match:	1ihiA_
Description:	3-alpha-hydroxysteroid dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits