YRC Public Data Repository - Protein Structure Prediction

Protein:	STE18
Organism:	Saccharomyces cerevisiae
Length:	110 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for STE18.

Description	E-value	Query Range	Subject Range
GBG_CANGA - Guanine nucleotide-binding protein subunit gamma OS=Candida glabrata (strain ATCC 2001 / CBS 138 / J... GBG_CANGA - Guanine nucleotide-binding protein subunit gamma OS=Candida glabrata GN=CAGL0M09207g PE=3 SV=1	115.0	[0..20]	[110..5]
GBG_ASHGO - Guanine nucleotide-binding protein subunit gamma OS=Ashbya gossypii (strain ATCC 10895 / CBS 109.51 ... GBG_ASHGO - Guanine nucleotide-binding protein subunit gamma OS=Ashbya gossypii GN=ACR176C PE=3 SV=2	109.0	[0..20]	[110..3]
GBG_KLULA - Guanine nucleotide-binding protein subunit gamma OS=Kluyveromyces lactis (strain ATCC 8585 / CBS 235... GBG_KLULA - Guanine nucleotide-binding protein subunit gamma OS=Kluyveromyces lactis GN=KLLA0E06138g PE=3 SV=1	107.0	[0..22]	[110..3]
GBG_NEUCR - Guanine nucleotide-binding protein subunit gamma OS=Neurospora crassa GN=gng-1 PE=3 SV=2 GBG_NEUCR - Guanine nucleotide-binding protein subunit gamma OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1...	68.0	[0..13]	[110..12]
gi\|216408347 - gi\|216408347\|gb\|ACJ72865.1\| G protein gamma subunit [Gibberella moniliformis] gi\|42554990, gi\|... - gi\|46125715\|ref\|XP_387411.1\| hypothetical protein FG07235.1 [Gibberella zeae PH-1], gi\|42554990\|gb\|E...	66.0	[0..13]	[86..12]
gi\|116192069, gi... - gi\|88181665\|gb\|EAQ89133.1\| guanine nucleotide-binding protein gamma subunit [Chaetomium globosum CBS...	64.0	[0..13]	[80..12]
gi\|115388523, gi... - gi\|115388523\|ref\|XP_001211767.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	63.0	[0..27]	[77..19]
gi\|86611487 - gi\|86611487\|gb\|ABD14415.1\| G-protein gamma subunit [Magnaporthe grisea] gi\|145614320, gi... - gi\|145614320\|ref\|XP_365973.2\| hypothetical protein MGG_10193 [Magnaporthe grisea 70-15], gi\|14502126...	62.0	[0..7]	[110..6]
gi\|111380687 - gi\|111380687\|gb\|ABH09719.1\| STE18-like protein [Penicillium marneffei]	61.0	[0..27]	[77..19]

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Predicted Domain #1

Region A:
Residues: [1-110]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSVQNSPRL QQPQEQQQQQ QQLSLKIKQL KLKRINELNN KLRKELSRER ITASNACLTI  60
   61 INYTSNTKDY TLPELWGYPV AGSNHFIEGL KNAQKNSQMS NSNSVCCTLM

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.47
Match:	1xhmB
Description:	The Crystal Structure of a Biologically Active Peptide (SIGK) Bound to a G Protein Beta:Gamma Heterodimer
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits