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View Structure Prediction Details

Protein: OPI3
Organism: Saccharomyces cerevisiae
Length: 206 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for OPI3.

Description E-value Query
Range
Subject
Range
gi|190409547 - gi|190409547|gb|EDV12812.1| unsaturated phospholipid N-methyltransferase [Saccharomyces cerevisiae R...
gi|207343828 - gi|207343828|gb|EDZ71167.1| YJR073Cp-like protein [Saccharomyces cerevisiae AWRI1631]
PEM2_YEAST - Phosphatidyl-N-methylethanolamine N-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 20450...
OPI3 - Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two ...
gi|151945140 - gi|151945140|gb|EDN63391.1| unsaturated phospholipid N-methyltransferase [Saccharomyces cerevisiae Y...
1.0E-90 [1..206] [1..206]
CHO1_SCHPO - Phosphatidyl-N-methylethanolamine N-methyltransferase OS=Schizosaccharomyces pombe (strain 972 / ATC...
cho1 - phosphatidyl-N-methylethanolamine N-methyltransferase
4.0E-77 [20..205] [32..220]
gi|22538478, gi|... - gi|6523815|gb|AAF14867.1|AF113126_1 phosphotidylethanolamine N-methyltransferase [Homo sapiens], gi|...
1.0E-74 [8..199] [37..228]
PEMT_RAT - Phosphatidylethanolamine N-methyltransferase OS=Rattus norvegicus GN=Pemt PE=1 SV=2
1.0E-73 [9..199] [1..191]
gi|2209105 - gi|2209105|gb|AAB61409.1| phospholipid methyltransferase [Schizosaccharomyces pombe]
1.0E-68 [20..189] [32..204]
gi|14716994 - gi|14716994|emb|CAC44161.1| putative phosphatidylethanolamine N-methyltransferase [Oncorhynchus myki...
5.0E-27 [9..84] [1..76]
gi|18481698 - gi|18481698|gb|AAL73521.1| phosphatidylethanolamine N-methyltransferase [Macaca radiata]
4.0E-16 [147..199] [1..53]

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Predicted Domain #1
Region A:
Residues: [1-132]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKESVQEIIQ QLIHSVDLQS SKFQLAIVCT MFNPIFWNIV ARMEYHKHSL TKMCGGARKG  60
   61 CYMLAATIFS LGIVRDMVYE SALREQPTCS LITGENWTKL GVALFGLGQV LVLSSMYKLG 120
  121 ITGTYLGDYF GI

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.641 0.004 endoplasmic reticulum a.7.1 Spectrin repeat
View Download 0.652 0.002 endoplasmic reticulum a.7.7 BAG domain
View Download 0.709 0.002 endoplasmic reticulum a.19.1 Fertilization protein
View Download 0.813 0.001 endoplasmic reticulum a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.742 0.001 endoplasmic reticulum f.18.1 F1F0 ATP synthase subunit A
View Download 0.813 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.742 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.709 N/A N/A a.19.1 Fertilization protein
View Download 0.652 N/A N/A a.7.7 BAG domain
View Download 0.641 N/A N/A a.7.1 Spectrin repeat
View Download 0.629 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.621 N/A N/A a.7.8 GAT domain
View Download 0.613 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.588 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.580 N/A N/A a.47.2 t-snare proteins
View Download 0.570 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.567 N/A N/A d.79.2 Tubulin/Dihydroxyacetone kinase C-terminal domain
View Download 0.493 N/A N/A a.1.1 Globin-like
View Download 0.490 N/A N/A a.7.7 BAG domain
View Download 0.478 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.476 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.467 N/A N/A f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.466 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.458 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.456 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.451 N/A N/A a.63.1 Apolipophorin-III
View Download 0.418 N/A N/A a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.402 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.394 N/A N/A a.63.1 Apolipophorin-III
View Download 0.387 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.386 N/A N/A d.173.1 Methionine synthase activation domain-like
View Download 0.382 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.377 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.376 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.369 N/A N/A a.47.2 t-snare proteins
View Download 0.369 N/A N/A a.7.1 Spectrin repeat
View Download 0.362 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.361 N/A N/A a.74.1 Cyclin-like
View Download 0.351 N/A N/A f.17.2 Cytochrome c oxidase subunit II-like, transmembrane region
View Download 0.349 N/A N/A a.7.8 GAT domain
View Download 0.348 N/A N/A d.67.3 Ribosome recycling factor, RRF
View Download 0.344 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.341 N/A N/A f.17.1 F1F0 ATP synthase subunit C
View Download 0.341 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.339 N/A N/A d.224.1 SufE-like
View Download 0.337 N/A N/A a.26.1 4-helical cytokines
View Download 0.332 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.330 N/A N/A a.7.8 GAT domain
View Download 0.321 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.320 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.317 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.315 N/A N/A a.7.1 Spectrin repeat
View Download 0.314 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.314 N/A N/A a.41.1 Domain of poly(ADP-ribose) polymerase
View Download 0.313 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.312 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.311 N/A N/A a.74.1 Cyclin-like
View Download 0.310 N/A N/A a.7.7 BAG domain
View Download 0.302 N/A N/A f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.299 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.299 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.299 N/A N/A a.24.1 Apolipoprotein
View Download 0.298 N/A N/A a.47.2 t-snare proteins
View Download 0.298 N/A N/A a.54.1 Domain of early E2A DNA-binding protein, ADDBP
View Download 0.298 N/A N/A a.7.1 Spectrin repeat
View Download 0.297 N/A N/A a.74.1 Cyclin-like
View Download 0.297 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.296 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.296 N/A N/A a.19.1 Fertilization protein
View Download 0.290 N/A N/A f.23.16 Subunit III of photosystem I reaction centre, PsaF
View Download 0.288 N/A N/A a.69.2 Ypt/Rab-GAP domain of gyp1p
View Download 0.286 N/A N/A c.55.1 Actin-like ATPase domain
View Download 0.285 N/A N/A a.39.1 EF-hand
View Download 0.283 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.283 N/A N/A c.2.1 NAD(P)-binding Rossmann-fold domains
View Download 0.279 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.277 N/A N/A d.56.1 GroEL-intermediate domain like
View Download 0.275 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.275 N/A N/A a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.275 N/A N/A a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.275 N/A N/A a.19.1 Fertilization protein
View Download 0.274 N/A N/A a.19.1 Fertilization protein
View Download 0.273 N/A N/A a.1.1 Globin-like
View Download 0.272 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.269 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.269 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.267 N/A N/A f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.266 N/A N/A f.1.3 delta-Endotoxin (insectocide), N-terminal domain
View Download 0.262 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.262 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.261 N/A N/A a.25.2 Thermoplasma ferritin-like 4-helical bundle
View Download 0.260 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.260 N/A N/A a.24.14 FAT domain of focal adhesion kinase
View Download 0.259 N/A N/A a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.258 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.258 N/A N/A a.7.8 GAT domain
View Download 0.257 N/A N/A a.7.8 GAT domain
View Download 0.253 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.253 N/A N/A a.22.1 Histone-fold
View Download 0.252 N/A N/A a.7.2 Enzyme IIa from lactose specific PTS, IIa-lac
View Download 0.251 N/A N/A a.7.1 Spectrin repeat
View Download 0.251 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.248 N/A N/A f.31.1 Photosystem I reaction center subunit XI, PsaL
View Download 0.247 N/A N/A a.149.1 RNase III endonuclease catalytic domain
View Download 0.246 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.246 N/A N/A a.22.1 Histone-fold
View Download 0.244 N/A N/A a.25.1 Ferritin-like
View Download 0.244 N/A N/A d.2.1 Lysozyme-like
View Download 0.240 N/A N/A a.24.1 Apolipoprotein
View Download 0.237 N/A N/A a.174.1 Double Clp-N motif
View Download 0.236 N/A N/A a.59.1 PAH2 domain
View Download 0.236 N/A N/A c.55.1 Actin-like ATPase domain
View Download 0.235 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.235 N/A N/A a.19.1 Fertilization protein
View Download 0.234 N/A N/A a.74.1 Cyclin-like
View Download 0.234 N/A N/A a.7.7 BAG domain
View Download 0.233 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.232 N/A N/A a.74.1 Cyclin-like
View Download 0.231 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.229 N/A N/A a.26.1 4-helical cytokines
View Download 0.227 N/A N/A a.7.5 Tubulin chaperone cofactor A
View Download 0.227 N/A N/A a.7.1 Spectrin repeat
View Download 0.227 N/A N/A f.14.1 Voltage-gated potassium channels
View Download 0.224 N/A N/A f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.219 N/A N/A a.48.1 N-terminal domain of cbl (N-cbl)
View Download 0.218 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.218 N/A N/A a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.217 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.214 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.214 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.212 N/A N/A g.36.1 Ferredoxin thioredoxin reductase (FTR), catalytic beta chain
View Download 0.212 N/A N/A a.22.1 Histone-fold
View Download 0.211 N/A N/A a.4.1 Homeodomain-like
View Download 0.208 N/A N/A f.35.1 Multidrug efflux transporter AcrB transmembrane domain
View Download 0.207 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.207 N/A N/A a.149.1 RNase III endonuclease catalytic domain
View Download 0.207 N/A N/A a.25.1 Ferritin-like
View Download 0.206 N/A N/A a.48.2 Transferrin receptor ectodomain, C-terminal domain
View Download 0.205 N/A N/A d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.204 N/A N/A a.29.5 alpha-ketoacid dehydrogenase kinase, N-terminal domain
View Download 0.204 N/A N/A a.62.1 Hepatitis B viral capsid (hbcag)
View Download 0.204 N/A N/A a.7.8 GAT domain
View Download 0.204 N/A N/A a.7.8 GAT domain
View Download 0.203 N/A N/A a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.203 N/A N/A d.185.1 LuxS/MPP-like metallohydrolase
View Download 0.201 N/A N/A d.122.1 ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase
View Download 0.201 N/A N/A a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.201 N/A N/A a.7.8 GAT domain
View Download 0.200 N/A N/A a.185.1 Gametocyte protein Pfg27

Predicted Domain #2
Region A:
Residues: [133-206]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMDERVTGFP FNVSNNPMYQ GSTLSFLGIA LYKGKPAGLV VSAVVYFMYK IALRWEEPFT  60
   61 AMIYANRDKA KKNM

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.684 0.238 mitochondrion a.17.1 p8-MTCP1
View Download 0.673 0.005 endoplasmic reticulum a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.619 0.004 endoplasmic reticulum a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.589 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.581 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.540 N/A N/A a.5.3 N-terminal domain of phosphatidylinositol transfer protein sec14p
View Download 0.530 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.491 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.481 N/A N/A a.118.8 TPR-like
View Download 0.461 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.437 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.424 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.409 N/A N/A a.4.1 Homeodomain-like
View Download 0.406 N/A N/A a.4.1 Homeodomain-like
View Download 0.404 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.392 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.378 N/A N/A a.52.1 Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin
View Download 0.370 N/A N/A a.20.1 PGBD-like
View Download 0.362 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.359 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.359 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.352 N/A N/A a.8.3 Families 57/38 glycoside transferase middle domain
View Download 0.351 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.345 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.343 N/A N/A a.17.1 p8-MTCP1
View Download 0.335 N/A N/A a.3.1 Cytochrome c
View Download 0.323 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.322 N/A N/A a.57.1 Protein HNS-dependent expression A; HdeA
View Download 0.319 N/A N/A a.64.2 Bacteriocin AS-48
View Download 0.310 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.304 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.303 N/A N/A a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.301 N/A N/A a.28.2 Colicin E immunity proteins
View Download 0.288 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.282 N/A N/A a.20.1 PGBD-like
View Download 0.278 N/A N/A a.4.1 Homeodomain-like
View Download 0.263 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.262 N/A N/A a.28.3 Retrovirus capsid protein C-terminal domain
View Download 0.260 N/A N/A a.4.5 "Winged helix" DNA-binding domain
View Download 0.250 N/A N/A a.60.5 Barrier-to-autointegration factor, BAF
View Download 0.249 N/A N/A a.20.1 PGBD-like
View Download 0.242 N/A N/A a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.242 N/A N/A a.3.1 Cytochrome c
View Download 0.237 N/A N/A d.39.1 Dynein light chain 8 (DLC8)
View Download 0.237 N/A N/A a.43.1 Met repressor-like
View Download 0.220 N/A N/A a.41.1 Domain of poly(ADP-ribose) polymerase
View Download 0.217 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.216 N/A N/A a.23.4 Mitochondrial import receptor subunit Tom20
View Download 0.209 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.204 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle