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View Structure Prediction Details

Protein: MNN5
Organism: Saccharomyces cerevisiae
Length: 586 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MNN5.

Description E-value Query
Range
Subject
Range
MNN5 - Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of th...
0.0 [1..586] [1..586]
gi|1658377 - gi|1658377|gb|AAB18320.1| unknown [Pichia pastoris]
0.0 [2..320] [5..305]

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Predicted Domain #1
Region A:
Residues: [1-136]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLIRLKKRKI LQVIVSAVVL ILFFCSVHND VSSSWLYGKK LRLPVLTRSN LKNNFYTTLV  60
   61 QAIVENKPAD SSPDLSKLHG AEGCSFANNV AAHDSGHDSD LSYESLSKCY NLNKTVQESL 120
  121 REVHSKFTDT LSGKLN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [137-302]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FSIPQREALF SGSEGIVTIG GGKYSVLAYT MIKKLRDTGT TLPIEVIIPP QDEGEDDFCK  60
   61 NWLPKFNGKC IYFSDIVPSK PLSDLKLTHF QLKVFGLIIS SFKRIIFLDA DNYAVKNLDL 120
  121 AFNTTSFNDT GLILWPDFWR RVTPPAFYNI IGSSINIGKR VRFVSD

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.49
Match: 1ga8A
Description: Galactosyltransferase LgtC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
mannosyltransferase activity 5.1732667004955 bayes_pls_golite062009
transferase activity, transferring hexosyl groups 4.02812104984198 bayes_pls_golite062009
transferase activity, transferring glycosyl groups 4.02134669395634 bayes_pls_golite062009
UDP-glycosyltransferase activity 3.59185576348855 bayes_pls_golite062009
alpha-1,2-mannosyltransferase activity 3.3757785630345 bayes_pls_golite062009
acetylgalactosaminyltransferase activity 2.9474291454591 bayes_pls_golite062009
polypeptide N-acetylgalactosaminyltransferase activity 2.69652752452892 bayes_pls_golite062009
transferase activity 2.3313878748424 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 1.79751747857925 bayes_pls_golite062009
catalytic activity 1.73979371332125 bayes_pls_golite062009
nucleotidyltransferase activity 0.641710647713692 bayes_pls_golite062009
binding 0.165472828059574 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [303-586]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DISPVSRYDP FVSNSNDYTP KERQEHFLKH VPLHDLDGTM PDLSSESGQM VIDKIRHFNT  60
   61 LLLALYYNVY GPTWYYKMIS QGTAGEGDKD TFFAAAHALN MPYYQVRTNF EFDGFFYQKD 120
  121 DYKGLALLQH DFEQDYKQYQ KAQQKVKANI EEFSKLDPDY TLDNGFLKTL MVNDDGSDLD 180
  181 IMFIHASFYK ADPWTLYHEN RFIGPNGEQV RGFRKPHRYG MDFELFLFND MRGSFCTTPK 240
  241 SQVIKFKYFT DKVNTPEWDA MCEYLTNHVN YLESTHKEAM GEKN

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


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Created and Maintained by: Michael Riffle