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View Structure Prediction Details

Protein: ATP12
Organism: Saccharomyces cerevisiae
Length: 325 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATP12.

Description E-value Query
Range
Subject
Range
gi|171106 - gi|171106|gb|AAA34442.1| ATP12 [Saccharomyces cerevisiae]
0.0 [1..325] [1..325]
ATP12_SCHPO - Protein atp12, mitochondrial OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=atp12 PE=2 SV...
atp12 - F1-ATPase chaperone Atp12
3.0E-81 [17..320] [2..270]
FBpp0303527, l(2... - The gene lethal (2) k14505 is referred to in FlyBase by the symbol Dmel\l(2)k14505 (CG8674, FBgn0021...
1.0E-76 [8..322] [3..264]
ATPF2_MOUSE - ATP synthase mitochondrial F1 complex assembly factor 2 OS=Mus musculus GN=Atpaf2 PE=1 SV=1
2.0E-72 [41..322] [36..273]
gi|9758094 - gi|9758094|dbj|BAB08538.1| unnamed protein product [Arabidopsis thaliana]
5.0E-68 [41..322] [73..316]
gi|15965140 - gi|15965140|ref|NP_385493.1| hypothetical protein SMc01277 [Sinorhizobium meliloti 1021]
gi|15074320 - gi|15074320|emb|CAC45966.1| Hypothetical protein [Sinorhizobium meliloti 1021]
2.0E-66 [49..320] [28..256]
gi|25374568 - pir||AF3374 hypothetical protein BMEI0980 [imported] - Brucella melitensis (strain 16M)
gi|17982939, gi|... - gi|17987263|ref|NP_539897.1| hypothetical protein BMEI0980 [Brucella melitensis 16M], gi|17982939|gb...
2.0E-62 [50..317] [31..254]
gi|25374572, gi|... - pir||F97538 hypothetical protein (AB009052) [imported] - Agrobacterium tumefaciens (strain C58, Cere...
gi|15888797, gi|... - gi|17935373|ref|NP_532163.1| hypothetical protein Atu1473 [Agrobacterium tumefaciens str. C58], gi|1...
1.0E-60 [49..312] [28..246]

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Predicted Domain #1
Region A:
Residues: [1-134]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLPSLRKGCF IVNSIRLKLP RFYSLNAQPL GTDNTIENNT PTETNRLSKT SQKFWEKVSL  60
   61 NRDVEKGKIA LQLDGRTIKT PLGNGIIVDN AKSLLAYLLK LEWSSLSSLS IKTHSLPLTS 120
  121 LVARCIDLQM TNEP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.427 0.147 mitochondrial matrix a.3.1 Cytochrome c
View Download 0.396 0.143 mitochondrial matrix a.1.1 Globin-like
View Download 0.555 0.034 mitochondrial matrix f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.516 N/A N/A a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.388 N/A N/A a.1.1 Globin-like
View Download 0.368 N/A N/A a.1.1 Globin-like
View Download 0.367 N/A N/A b.60.1 Lipocalins
View Download 0.362 N/A N/A a.1.1 Globin-like
View Download 0.352 N/A N/A f.18.1 F1F0 ATP synthase subunit A
View Download 0.351 N/A N/A a.61.1 Retroviral matrix proteins
View Download 0.325 N/A N/A f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.307 N/A N/A a.3.1 Cytochrome c
View Download 0.284 N/A N/A a.126.1 Serum albumin-like
View Download 0.279 N/A N/A a.142.1 PTS-regulatory domain, PRD
View Download 0.274 N/A N/A a.22.1 Histone-fold
View Download 0.238 N/A N/A a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.234 N/A N/A a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.223 N/A N/A c.45.1 (Phosphotyrosine protein) phosphatases II
View Download 0.213 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.203 N/A N/A b.60.1 Lipocalins

Predicted functions:

Term Confidence Notes
binding 1.72024350544232 bayes_pls_golite062009
protein binding 1.2388395457113 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [135-213]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GCDPQLVAKI GGNSDVIKNQ LLRYLDTDTL LVFSPMNEFE GRLRNAQNEL YIPIIKGMEE  60
   61 FLRNFSSESN IRLQILDAD

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.655 0.026 mitochondrial matrix d.58.7 RNA-binding domain, RBD
View Download 0.818 0.026 mitochondrial matrix f.14.1 Voltage-gated potassium channels
View Download 0.612 0.026 mitochondrial matrix d.52.7 Ribosome-binding factor A, RbfA
View Download 0.563 0.026 mitochondrial matrix d.58.23 Probable ACP-binding domain of malonyl-CoA ACP transacylase
View Download 0.512 0.026 mitochondrial matrix d.58.7 RNA-binding domain, RBD
View Download 0.467 0.026 mitochondrial matrix d.58.4 Dimeric alpha+beta barrel
View Download 0.466 0.026 mitochondrial matrix d.68.6 DNA-binding protein Sso10b (AlbA)
View Download 0.464 0.026 mitochondrial matrix d.58.11 EF-G/eEF-2 domains III and V
View Download 0.448 0.026 mitochondrial matrix a.6.1 Putative DNA-binding domain
View Download 0.446 0.026 mitochondrial matrix d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.426 0.026 mitochondrial matrix a.28.1 ACP-like
View Download 0.418 0.026 mitochondrial matrix d.58.17 Metal-binding domain
View Download 0.416 0.026 mitochondrial matrix d.58.48 MTH1187-like
View Download 0.414 0.026 mitochondrial matrix d.58.10 Acylphosphatase-like
View Download 0.409 0.026 mitochondrial matrix a.4.1 Homeodomain-like
View Download 0.397 0.026 mitochondrial matrix d.58.3 Protease propeptides/inhibitors
View Download 0.396 0.026 mitochondrial matrix a.77.1 DEATH domain
View Download 0.395 0.026 mitochondrial matrix a.15.1 TAF(II)230 TBP-binding fragment
View Download 0.386 0.026 mitochondrial matrix d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.385 0.026 mitochondrial matrix a.46.1 Methionine synthase domain
View Download 0.385 0.026 mitochondrial matrix d.58.7 RNA-binding domain, RBD
View Download 0.384 0.026 mitochondrial matrix a.60.2 RuvA domain 2-like
View Download 0.382 0.026 mitochondrial matrix d.58.8 Viral DNA-binding domain
View Download 0.380 0.026 mitochondrial matrix d.58.17 Metal-binding domain
View Download 0.380 0.026 mitochondrial matrix a.6.1 Putative DNA-binding domain
View Download 0.376 0.026 mitochondrial matrix f.34.1 Mechanosensitive channel protein MscS (YggB), transmembrane region
View Download 0.371 0.026 mitochondrial matrix d.58.12 eEF-1beta-like
View Download 0.369 0.026 mitochondrial matrix d.58.24 CheY-binding domain of CheA
View Download 0.364 0.026 mitochondrial matrix d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.362 0.026 mitochondrial matrix d.68.1 Translation initiation factor IF3, C-terminal domain
View Download 0.354 0.026 mitochondrial matrix d.58.49 YajQ-like
View Download 0.347 0.026 mitochondrial matrix d.58.18 Regulatory domain in the aminoacid metabolism
View Download 0.338 0.026 mitochondrial matrix d.57.1 DNA damage-inducible protein DinI
View Download 0.338 0.026 mitochondrial matrix d.58.8 Viral DNA-binding domain
View Download 0.335 0.026 mitochondrial matrix a.6.1 Putative DNA-binding domain
View Download 0.333 0.026 mitochondrial matrix c.102.1 Cell-division inhibitor MinC, N-terminal domain
View Download 0.329 0.026 mitochondrial matrix d.58.11 EF-G/eEF-2 domains III and V
View Download 0.323 0.026 mitochondrial matrix d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.321 0.026 mitochondrial matrix a.4.5 "Winged helix" DNA-binding domain
View Download 0.315 0.026 mitochondrial matrix a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.315 0.026 mitochondrial matrix d.58.7 RNA-binding domain, RBD
View Download 0.297 0.026 mitochondrial matrix d.52.4 YhbC-like, N-terminal domain
View Download 0.289 0.026 mitochondrial matrix a.4.3 ARID-like
View Download 0.287 0.026 mitochondrial matrix d.58.40 D-ribose-5-phosphate isomerase (RpiA), lid domain
View Download 0.285 0.026 mitochondrial matrix a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.271 0.026 mitochondrial matrix a.4.8 Ribosomal protein S18
View Download 0.269 0.026 mitochondrial matrix f.13.1 Family A G protein-coupled receptor-like
View Download 0.268 0.026 mitochondrial matrix a.147.1 Bcr-Abl oncoprotein oligomerization domain
View Download 0.267 0.026 mitochondrial matrix d.40.1 CI-2 family of serine protease inhibitors
View Download 0.265 0.026 mitochondrial matrix a.2.8 Eukaryotic DNA topoisomerase I, dispensable insert domain
View Download 0.265 0.026 mitochondrial matrix d.58.5 GlnB-like
View Download 0.259 0.026 mitochondrial matrix d.58.48 MTH1187-like
View Download 0.255 0.026 mitochondrial matrix a.42.1 MDM2
View Download 0.253 0.026 mitochondrial matrix a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.253 0.026 mitochondrial matrix d.58.5 GlnB-like
View Download 0.249 0.026 mitochondrial matrix a.60.9 lambda integrase-like, N-terminal domain
View Download 0.246 0.026 mitochondrial matrix a.64.2 Bacteriocin AS-48
View Download 0.243 0.026 mitochondrial matrix a.22.1 Histone-fold
View Download 0.236 0.026 mitochondrial matrix d.94.1 HPr-like
View Download 0.229 0.026 mitochondrial matrix a.100.1 6-phosphogluconate dehydrogenase C-terminal domain-like
View Download 0.227 0.026 mitochondrial matrix a.2.7 tRNA-binding arm
View Download 0.227 0.026 mitochondrial matrix a.144.2 Ribosomal protein L20
View Download 0.227 0.026 mitochondrial matrix d.33.1 Bacterial protein-export protein SecB
View Download 0.218 0.026 mitochondrial matrix d.68.4 YhbY-like
View Download 0.215 0.026 mitochondrial matrix d.68.5 C-terminal domain of ProRS
View Download 0.213 0.026 mitochondrial matrix d.58.44 Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains
View Download 0.213 0.026 mitochondrial matrix a.47.2 t-snare proteins
View Download 0.210 0.026 mitochondrial matrix d.52.3 Prokaryotic type KH domain (KH-domain type II)
View Download 0.209 0.026 mitochondrial matrix d.52.1 Alpha-lytic protease prodomain
View Download 0.208 0.026 mitochondrial matrix a.22.1 Histone-fold
View Download 0.207 0.026 mitochondrial matrix a.4.5 "Winged helix" DNA-binding domain
View Download 0.204 0.026 mitochondrial matrix g.57.1 Serine proteinase inhibitor lekti
View Download 0.204 0.026 mitochondrial matrix a.61.1 Retroviral matrix proteins
View Download 0.202 0.026 mitochondrial matrix a.180.1 N-terminal, cytoplasmic domain of anti-sigmaE factor RseA
View Download 0.200 0.026 mitochondrial matrix d.58.43 Mechanosensitive channel protein MscS (YggB), C-terminal domain

Predicted Domain #3
Region A:
Residues: [214-325]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IHGLRGNQQS DIVKNAAKKY MSSLSPWDLA ILEKTVLTTK SFICGVLLLE NKKDTANLIP  60
   61 ALKTDMDNIV RAATLETIFQ VEKWGEVEDT HDVDKRDIRR KIHTAAIAAF KQ

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.457 0.022 mitochondrial matrix a.74.1 Cyclin-like
View Download 0.705 0.020 mitochondrial matrix a.47.2 t-snare proteins
View Download 0.562 0.013 mitochondrial matrix a.24.9 alpha-catenin/vinculin
View Download 0.529 0.008 mitochondrial matrix a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.512 0.002 mitochondrial matrix a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.407 N/A N/A a.1.1 Globin-like
View Download 0.365 N/A N/A a.40.1 Calponin-homology domain, CH-domain
View Download 0.341 N/A N/A a.7.8 GAT domain
View Download 0.328 N/A N/A a.112.1 Description not found.
View Download 0.306 N/A N/A a.39.2 Insect pheromon/odorant-binding proteins
View Download 0.299 N/A N/A a.24.9 alpha-catenin/vinculin
View Download 0.297 N/A N/A a.142.1 PTS-regulatory domain, PRD
View Download 0.296 N/A N/A g.36.1 Ferredoxin thioredoxin reductase (FTR), catalytic beta chain
View Download 0.296 N/A N/A i.11.1 Computational models partly based on NMR data
View Download 0.296 N/A N/A a.1.1 Globin-like
View Download 0.283 N/A N/A d.56.1 GroEL-intermediate domain like
View Download 0.280 N/A N/A g.53.1 TAZ domain
View Download 0.277 N/A N/A a.133.1 Phospholipase A2, PLA2
View Download 0.273 N/A N/A a.24.10 Histidine-containing phosphotransfer domain, HPT domain
View Download 0.270 N/A N/A a.24.3 Cytochromes
View Download 0.255 N/A N/A a.24.3 Cytochromes
View Download 0.255 N/A N/A a.60.9 lambda integrase-like, N-terminal domain
View Download 0.251 N/A N/A a.7.7 BAG domain
View Download 0.251 N/A N/A a.24.11 Bacterial GAP domain
View Download 0.251 N/A N/A a.29.2 Bromodomain
View Download 0.249 N/A N/A a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.248 N/A N/A d.188.1 Prokaryotic ribosomal protein L17
View Download 0.248 N/A N/A a.185.1 Gametocyte protein Pfg27
View Download 0.246 N/A N/A a.5.4 Elongation factor TFIIS domain 2
View Download 0.240 N/A N/A a.59.1 PAH2 domain
View Download 0.239 N/A N/A d.110.1 Profilin (actin-binding protein)
View Download 0.239 N/A N/A d.58.20 NAD-binding domain of HMG-CoA reductase
View Download 0.238 N/A N/A a.6.1 Putative DNA-binding domain
View Download 0.233 N/A N/A a.60.10 Enzyme I of the PEP:sugar phosphotransferase system HPr-binding (sub)domain
View Download 0.233 N/A N/A a.162.1 Pre-protein croslinking domain of SecA
View Download 0.226 N/A N/A a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.224 N/A N/A a.4.12 TrpR-like
View Download 0.222 N/A N/A a.71.2 Helical domain of Sec23/24
View Download 0.222 N/A N/A d.92.2 beta-N-acetylhexosaminidase-like domain
View Download 0.221 N/A N/A a.4.1 Homeodomain-like
View Download 0.218 N/A N/A a.29.2 Bromodomain
View Download 0.213 N/A N/A c.23.12 Formate/glycerate dehydrogenase catalytic domain-like
View Download 0.213 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.205 N/A N/A f.13.1 Family A G protein-coupled receptor-like
View Download 0.202 N/A N/A a.24.3 Cytochromes


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle