YRC Public Data Repository - Protein Structure Prediction

Protein:	ERG20
Organism:	Saccharomyces cerevisiae
Length:	352 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERG20.

Description	E-value	Query Range	Subject Range
gi\|168269804, gi... - gi\|168269804\|dbj\|BAG10029.1\| farnesyl pyrophosphate synthetase [synthetic construct], gi\|123998535\|g... FDPS - farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, ger... gi\|114560081, gi... - gi\|114560089\|ref\|XP_001160292.1\| PREDICTED: farnesyl diphosphate synthase isoform 8 [Pan troglodytes...	6.0E-98	[7..352]	[78..419]
gi\|149048093, gi... - gi\|37590777\|gb\|AAH59125.1\| Farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethy...	2.0E-95	[6..352]	[11..353]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	6.0E-95	[7..352]	[12..353]
FPPS_BOVIN - Farnesyl pyrophosphate synthase OS=Bos taurus GN=FDPS PE=1 SV=1	5.0E-94	[7..352]	[12..353]
FPPS1_ARATH - Farnesyl pyrophosphate synthase 1, mitochondrial OS=Arabidopsis thaliana GN=FPS1 PE=2 SV=2	6.0E-94	[9..352]	[47..384]

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Predicted Domain #1

Region A:
Residues: [1-168]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASEKEIRRE RFLNVFPKLV EELNASLLAY GMPKEACDWY AHSLNYNTPG GKLNRGLSVV  60
   61 DTYAILSNKT VEQLGQEEYE KVAILGWCIE LLQAYFLVAD DMMDKSITRR GQPCWYKVPE 120
  121 VGEIAINDAF MLEAAIYKLL KSHFRNEKYY IDITELFHEV TFQTELGQ

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [199-218]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYYSFYLPVA LAMYVAGITD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	976.0103
Match:	1fps__
Description:	Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [169-191]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LMDLITAPED KVDLSKFSLK KHS

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [238-314]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IQDDYLDCFG TPEQIGKIGT DIQDNKCSWV INKALELASA EQRKTLDENY GKKDSVAEAK  60
   61 CKKIFNDLKI EQLYHEY

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	976.0103
Match:	1fps__
Description:	Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [192-198]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FIVTFKT

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [219-237]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EKDLKQARDV LIPLGEYFQ

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [315-352]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EESIAKDLKA KISQVDESRG FKADVLTAFL NKVYKRSK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	976.0103
Match:	1fps__
Description:	Farnesyl diphosphate synthase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits