| Protein: | KHA1 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 873 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KHA1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..873] | [1..873] |
|
|
0.0 | [1..655] | [12..639] |
|
|
0.0 | [1..625] | [39..638] |
|
Region A: Residues: [1-451] |
1 11 21 31 41 51
| | | | | |
1 MANTVGGILS GVNPFHYNSS SPLTLFLFQA CLILLVCNLI HIPFSMMRQP KVISEVISGV 60
61 ILGPTIFGQI PNYTNTIFPT SSIPGLNLVA NLGIILFMFF LGLEVDIAFI KKHLKKALVI 120
121 GIVTLAVPFG FGCLLAIPLF HTYANKTEGE RHIKFSVFMV FIAVSISVTA FPVLCRILNE 180
181 LRLIKDRAGI VVLAAGIIND IMGWILLALS IILSSAEGSP VNTVYILLIT FAWFLIYFFP 240
241 LKYLLRWVLI RTHELDRSKP SPLATMCILF IMFISAYFTD IIGVHPIFGA FIAGLVVPRD 300
301 DHYVVKLTER MEDIPNIVFI PIYFAVAGLN VDLTLLNEGR DWGYVFATIG IAIFTKIISG 360
361 TLTAKLTGLF WREATAAGVL MSCKGIVEIV VLTVGLNAGI ISRKIFGMFV LMALVSTFVT 420
421 TPLTQLVYPD SYRDGVRKSL STPAEDDGAA D
|
| Detection Method: |  |
| Confidence: | 16.187087 |
| Match: | PF00999 |
| Description: | Sodium/hydrogen exchanger family |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [452-551] |
1 11 21 31 41 51
| | | | | |
1 GLDSEGVDKT EINTQLNSLA DVSKYRIGEL TTVINTTEAI SPSLKLLNYL SLGVSPKPKN 60
61 NKHKNETSLS RMTTATDSTL KSNTFKIKKM VHIWSKSVDD
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.767 | a.141.1 | Frizzled cystein-rich domain |
| View | Download | 0.730 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.655 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.651 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.645 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.767 | a.141.1 | Frizzled cystein-rich domain |
| View | Download | 0.730 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.655 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.651 | a.57.1 | Protein HNS-dependent expression A; HdeA |
| View | Download | 0.645 | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.538 | a.64.1 | Saposin |
| View | Download | 0.504 | a.26.1 | 4-helical cytokines |
| View | Download | 0.504 | a.64.1 | Saposin |
| View | Download | 0.501 | a.118.1 | ARM repeat |
| View | Download | 0.476 | a.180.1 | N-terminal, cytoplasmic domain of anti-sigmaE factor RseA |
| View | Download | 0.452 | a.181.1 | Antibiotic binding domain of TipA-like multidrug resistance regulators |
| View | Download | 0.440 | a.165.1 | Myosin phosphatase inhibitor 17kDa protein, CPI-17 |
| View | Download | 0.417 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.417 | a.24.7 | FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP) |
| View | Download | 0.404 | a.24.4 | Hemerythrin |
| View | Download | 0.399 | a.7.6 | Ribosomal protein S20 |
| View | Download | 0.395 | a.39.1 | EF-hand |
| View | Download | 0.394 | a.42.1 | MDM2 |
| View | Download | 0.394 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.371 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.369 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.354 | a.24.3 | Cytochromes |
| View | Download | 0.354 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.351 | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.347 | a.24.13 | Domain of the SRP/SRP receptor G-proteins |
| View | Download | 0.347 | a.69.1 | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| View | Download | 0.336 | a.4.12 | TrpR-like |
| View | Download | 0.332 | a.100.1 | 6-phosphogluconate dehydrogenase C-terminal domain-like |
| View | Download | 0.331 | a.74.1 | Cyclin-like |
| View | Download | 0.331 | c.25.1 | Ferredoxin reductase-like, C-terminal NADP-linked domain |
| View | Download | 0.330 | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.315 | d.58.13 | Anticodon-binding domain of PheRS |
| View | Download | 0.314 | a.1.1 | Globin-like |
| View | Download | 0.313 | a.60.5 | Barrier-to-autointegration factor, BAF |
| View | Download | 0.306 | a.1.1 | Globin-like |
| View | Download | 0.288 | a.61.1 | Retroviral matrix proteins |
| View | Download | 0.278 | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.277 | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.269 | a.95.1 | Influenza virus matrix protein M1 |
| View | Download | 0.267 | a.23.2 | Diol dehydratase, gamma subunit |
| View | Download | 0.253 | f.1.4 | Bcl-2 inhibitors of programmed cell death |
| View | Download | 0.239 | c.51.3 | B12-dependend dehydatases associated subunit |
| View | Download | 0.238 | a.39.4 | Hypothetical protein MTH865 |
| View | Download | 0.230 | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.220 | a.4.2 | Methylated DNA-protein cysteine methyltransferase, C-terminal domain |
| View | Download | 0.218 | a.121.1 | Tetracyclin repressor-like, C-terminal domain |
| View | Download | 0.215 | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.215 | a.1.1 | Globin-like |
| View | Download | 0.215 | a.39.1 | EF-hand |
| View | Download | 0.211 | a.46.2 | Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain |
| View | Download | 0.207 | a.36.1 | Signal peptide-binding domain |
| View | Download | 0.203 | a.118.9 | ENTH/VHS domain |
| View | Download | 0.202 | a.1.1 | Globin-like |
|
Region A: Residues: [552-656] |
1 11 21 31 41 51
| | | | | |
1 VDTNLSVIDE KLTPFEGVGA LRAIHLRLLT ERTTDLLQSS SLYNDDPHFT ANTDSLLQIF 60
61 DIFSNLSKIP FSSEVIFSTM REKAANIATM KMDSTDLILL PLKGA
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.774 | 0.164 | monovalent inorganic cation transport | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.649 | 0.004 | monovalent inorganic cation transport | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.556 | 0.002 | monovalent inorganic cation transport | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.774 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.725 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.725 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.649 | N/A | N/A | a.60.9 | lambda integrase-like, N-terminal domain |
| View | Download | 0.567 | N/A | N/A | a.4.5 | "Winged helix" DNA-binding domain |
| View | Download | 0.556 | N/A | N/A | a.24.17 | Group V grass pollen allergen |
| View | Download | 0.550 | N/A | N/A | c.13.2 | Anti-sigma factor antagonist SpoIIaa |
| View | Download | 0.549 | N/A | N/A | a.4.1 | Homeodomain-like |
| View | Download | 0.537 | N/A | N/A | a.23.1 | HSC20 (HSCB), C-terminal oligomerisation domain |
| View | Download | 0.535 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.520 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.512 | N/A | N/A | a.4.6 | C-terminal effector domain of the bipartite response regulators |
| View | Download | 0.483 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.476 | N/A | N/A | a.85.1 | Hemocyanin, N-terminal domain |
| View | Download | 0.474 | N/A | N/A | a.24.10 | Histidine-containing phosphotransfer domain, HPT domain |
| View | Download | 0.452 | N/A | N/A | a.45.1 | Glutathione S-transferase (GST), C-terminal domain |
| View | Download | 0.450 | N/A | N/A | a.118.11 | Cytochrome c oxidase subunit E |
| View | Download | 0.440 | N/A | N/A | a.56.1 | CO dehydrogenase ISP C-domain like |
| View | Download | 0.424 | N/A | N/A | a.71.2 | Helical domain of Sec23/24 |
| View | Download | 0.420 | N/A | N/A | c.95.1 | Thiolase-like |
| View | Download | 0.419 | N/A | N/A | d.8.1 | Urease, gamma-subunit |
| View | Download | 0.410 | N/A | N/A | a.7.8 | GAT domain |
| View | Download | 0.405 | N/A | N/A | a.1.2 | alpha-helical ferredoxin |
| View | Download | 0.399 | N/A | N/A | d.88.1 | SRF-like |
| View | Download | 0.390 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.378 | N/A | N/A | f.34.1 | Mechanosensitive channel protein MscS (YggB), transmembrane region |
| View | Download | 0.365 | N/A | N/A | a.52.1 | Bifunctional inhibitor/lipid-transfer protein/seed storage 2S albumin |
| View | Download | 0.362 | N/A | N/A | a.74.1 | Cyclin-like |
| View | Download | 0.350 | N/A | N/A | a.151.1 | Glutamyl tRNA-reductase dimerization domain |
| View | Download | 0.349 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.341 | N/A | N/A | a.7.1 | Spectrin repeat |
| View | Download | 0.341 | N/A | N/A | a.69.1 | C-terminal domain of alpha and beta subunits of F1 ATP synthase |
| View | Download | 0.327 | N/A | N/A | d.150.1 | 4'-phosphopantetheinyl transferase |
| View | Download | 0.325 | N/A | N/A | d.21.1 | Diaminopimelate epimerase-like |
| View | Download | 0.324 | N/A | N/A | c.102.1 | Cell-division inhibitor MinC, N-terminal domain |
| View | Download | 0.322 | N/A | N/A | c.45.1 | (Phosphotyrosine protein) phosphatases II |
| View | Download | 0.320 | N/A | N/A | d.106.1 | Sterol carrier protein, SCP |
| View | Download | 0.318 | N/A | N/A | f.15.1 | Small-conductance potassium channel |
| View | Download | 0.317 | N/A | N/A | a.81.1 | N-terminal domain of DnaB helicase |
| View | Download | 0.314 | N/A | N/A | a.80.1 | DNA polymerase III clamp loader subunits, C-terminal domain |
| View | Download | 0.305 | N/A | N/A | c.52.2 | tRNA splicing endonuclease, C-terminal domain |
| View | Download | 0.296 | N/A | N/A | d.110.3 | PYP-like sensor domain (PAS domain) |
| View | Download | 0.289 | N/A | N/A | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.287 | N/A | N/A | f.36.1 | Neurotransmitter-gated ion-channel pransmembrane pore |
| View | Download | 0.284 | N/A | N/A | a.24.9 | alpha-catenin/vinculin |
| View | Download | 0.284 | N/A | N/A | a.118.8 | TPR-like |
| View | Download | 0.279 | N/A | N/A | a.142.1 | PTS-regulatory domain, PRD |
| View | Download | 0.279 | N/A | N/A | a.47.2 | t-snare proteins |
| View | Download | 0.275 | N/A | N/A | c.23.1 | CheY-like |
| View | Download | 0.269 | N/A | N/A | d.202.1 | Transcription factor NusA, N-terminal domain |
| View | Download | 0.264 | N/A | N/A | d.79.1 | YjgF-like |
| View | Download | 0.263 | N/A | N/A | a.90.1 | Transcription factor STAT-4 N-domain |
| View | Download | 0.260 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.257 | N/A | N/A | d.68.1 | Translation initiation factor IF3, C-terminal domain |
| View | Download | 0.252 | N/A | N/A | a.4.9 | Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3 |
| View | Download | 0.246 | N/A | N/A | a.26.1 | 4-helical cytokines |
| View | Download | 0.239 | N/A | N/A | a.64.1 | Saposin |
| View | Download | 0.235 | N/A | N/A | a.51.1 | Cytochrome c oxidase subunit h |
| View | Download | 0.234 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.231 | N/A | N/A | c.37.1 | P-loop containing nucleoside triphosphate hydrolases |
| View | Download | 0.223 | N/A | N/A | a.21.1 | HMG-box |
| View | Download | 0.220 | N/A | N/A | a.24.4 | Hemerythrin |
| View | Download | 0.220 | N/A | N/A | a.118.1 | ARM repeat |
| View | Download | 0.218 | N/A | N/A | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| View | Download | 0.218 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.218 | N/A | N/A | a.1.1 | Globin-like |
| View | Download | 0.216 | N/A | N/A | c.84.1 | Phosphoglucomutase, first 3 domains |
| View | Download | 0.215 | N/A | N/A | d.2.1 | Lysozyme-like |
| View | Download | 0.215 | N/A | N/A | b.55.1 | PH domain-like |
| View | Download | 0.209 | N/A | N/A | a.46.1 | Methionine synthase domain |
| View | Download | 0.208 | N/A | N/A | a.59.1 | PAH2 domain |
| View | Download | 0.207 | N/A | N/A | a.130.1 | Chorismate mutase II |
| View | Download | 0.207 | N/A | N/A | d.21.1 | Diaminopimelate epimerase-like |
| View | Download | 0.206 | N/A | N/A | d.169.1 | C-type lectin-like |
| View | Download | 0.205 | N/A | N/A | d.236.1 | DNA-binding protein Tfx |
| View | Download | 0.201 | N/A | N/A | a.74.1 | Cyclin-like |
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Region A: Residues: [657-873] |
1 11 21 31 41 51
| | | | | |
1 SYEYRGSPVF IDEKYANFDH IYSHLLGLNE LSSTFFKSIF QSLKANFAVQ ISNTYGRLNA 60
61 DRFKRKRFNL LLPKPYLTQS DYLGLYLLLL ICYRDGYNND NASCSIFINS KNIDFAKDLS 120
121 TAFAEHDWLN ESTIKIVDIP FETKVPEEAI EKPSFIETVL DVGLSDTALA DIEETTFIIG 180
181 EDLPDESEPF SEEVRTVIFE GSNRRFDTLI VHHFSSE
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
