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View Structure Prediction Details

Protein: CYR1
Organism: Saccharomyces cerevisiae
Length: 2026 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYR1.

Description E-value Query
Range		 Subject
Range
gi|171360 - gi|171360|gb|AAA34549.1| adenylate cyclase
 1713.0 [0..1] [2026..1]
gi|38099318, gi|... - gi|39964959|ref|XP_365053.1| hypothetical protein MGG_09898 [Magnaporthe grisea 70-15], gb|EAA46677....
 1235.0 [0..73] [2020..21]
gi|2267008 - gi|2267008|gb|AAC34139.1| adenylate cyclase [Magnaporthe grisea]
 1234.0 [0..73] [2020..21]
CYAA_PODAS - Adenylate cyclase OS=Podospora anserina PE=3 SV=1
 1228.0 [0..60] [2024..8]
gi|7228262 - gi|7228262|emb|CAB77164.1| adenylate cyclase [Botryotinia fuckeliana]
 1166.0 [0..61] [2004..9]
gi|10505261 - gi|10505261|gb|AAG18428.1|AF295379_1 adenylyl cyclase [Candida albicans]
 1117.0 [0..680] [2024..308]
gi|103488936 - gi|103488936|gb|ABF71879.1| adenylate cyclase [Sclerotinia sclerotiorum]
 1115.0 [0..61] [2004..9]

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Predicted Domain #1
Region A:
Residues: [1-409] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSKPDTGSE ISGPQRQEEQ EQQIEQSSPT EANDRSIHDE VPKVKKRHEQ NSGHKSRRNS  60
   61 AYSYYSPRSL SMTKSRESIT PNGMDDVSIS NVEHPRPTEP KIKRGPYLLK KTLSSLSMTS 120
  121 ANSTHDDNKD HGYALNSSKT HNYTSTHNHH DGHHDHHHVQ FFPNRKPSLA ETLFKRFSGS 180
  181 NSHDGNKSGK ESKVANLSLS TVNPAPANRK PSKDSTLSNH LADNVPSTLR RKVSSLVRGS 240
  241 SVHDINNGIA DKQIRPKAVA QSENTLHSSD VPNSKRSHRK SFLLGSTSSS SSRRGSNVSS 300
  301 MTNSDSASMA TSGSHVLQHN VSNVSPTTKS KDSVNSESAD HTNNKSEKVT PEYNENIPEN 360
  361 SNSDNKREAT TPTIETPISC KPSLFRLDTN LEDVTDITKT VPPTAVNST

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 13.38
Match:
Description: No description for 1i3qA was found.

Predicted Domain #2
Region A:
Residues: [410-553] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNSTHGTETA SPKTVIMPEG PRKSVSMADL SVAAAAPNGE FTSTSNDRSQ WVAPQSWDVE  60
   61 TKRKKTKPKG RSKSRRSSID ADELDPMSPG PPSKKDSRHH HDRKDNESMV TAGDSNSSFV 120
  121 DICKENVPND SKTALDTKSV NRLK

[Run NCBI BLAST on this sequence.]

Detection Method: ab initio
Confidence: 13.52
Match:
Description: No description for 1ldvA was found.

Predicted Domain #3
Region A:
Residues: [554-659] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNLAMSPPSI RYAPSNLDGD YDTSSTSSSL PSSSISSEDT SSCSDSSSYT NAYMEANREQ  60
   61 DNKTPILNKT KSYTKKFTSS SVNMNSPDGA QSSGLLLQDE KDDEVE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1dfjI
Description: Ribonuclease inhibitor
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [660-719] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CQLEHYYKDF SDLDPKRHYA IRIFNTDDTF TTLSCTPATT VEEIIPALKR KFNITAQGNF  60
   61

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1dfjI
Description: Ribonuclease inhibitor
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [720-777] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QISLKVGKLS KILRPTSKPI LIERKLLLLN GYRKSDPLHI MGIEDLSFVF KFLFHPVT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1dfjI
Description: Ribonuclease inhibitor
Matching Structure (courtesy of the PDB):

Predicted Domain #6
Region A:
Residues: [778-947] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PSHFTPEQEQ RIMRSEFVHV DLRNMDLTTP PIIFYQHTSE IESLDVSNNA NIFLPLEFIE  60
   61 SSIKLLSLRM VNIRASKFPS NITKAYKLVS LELQRNFIRK VPNSIMKLSN LTILNLQCNE 120
  121 LESLPAGFVE LKNLQLLDLS SNKFMHYPEV INYCTNLLQI DLSYNKIQSL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.39794
Match: 1dfjI
Description: Ribonuclease inhibitor
Matching Structure (courtesy of the PDB):

Predicted Domain #7
Region A:
Residues: [948-1030] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PQSTKYLVKL AKMNLSHNKL NFIGDLSEMT DLRTLNLRYN RISSIKTNAS NLQNLFLTDN  60
   61 RISNFEDTLP KLRALEIQEN PIT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 9.045757
Match: 1k5dC
Description: Rna1p (RanGAP1), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted Domain #8
Region A:
Residues: [1031-1123] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SISFKDFYPK NMTSLTLNKA QLSSIPGELL TKLSFLEKLE LNQNNLTRLP QEISKLTKLV  60
   61 FLSVARNKLE YIPPELSQLK SLRTLDLHSN NIR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 81.751666
Match: 1g9uA
Description: Leucine rich effector protein YopM
Matching Structure (courtesy of the PDB):

Predicted Domain #9
Region A:
Residues: [1124-1185] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DFVDGMENLE LTSLNISSNA FGNSSLENSF YHNMSYGSKL SKSLMFFIAA DNQFDDAMWP  60
   61 LF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #10
Region A:
Residues: [1186-1300] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NCFVNLKVLN LSYNNFSDVS HMKLESITEL YLSGNKLTTL SGDTVLKWSS LKTLMLNSNQ  60
   61 MLSLPAELSN LSQLSVFDVG ANQLKYNISN YHYDWNWRNN KELKYLNFSG NRRFE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 3.39794
Match: 1kooA
Description: mRNA export factor tap
Matching Structure (courtesy of the PDB):

Predicted Domain #11
Region A:
Residues: [1301-1352] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IKSFISHDID ADLSDLTVLP QLKVLGLMDV TLNTTKVPDE NVNFRLRTTA SI

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #12
Region A:
Residues: [1353-1649] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 INGMRYGVAD TLGQRDYVSS RDVTFERFRG NDDECLLCLH DSKNQNADYG HNISRIVRDI  60
   61 YDKILIRQLE RYGDETDDNI KTALRFSFLQ LNKEINGMLN SVDNGADVAN LSYADLLSGA 120
  121 CSTVIYIRGK KLFAANLGDC MAILSKNNGD YQTLTKQHLP TKREEYERIR ISGGYVNNGK 180
  181 LDGVVDVSRA VGFFDLLPHI HASPDISVVT LTKADEMLIV ATHKLWEYMD VDTVCDIARE 240
  241 NSTDPLRAAA ELKDHAMAYG CTENITILCL ALYENIQQQN RFTLNKNSLM TRRSTFE

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 178.69897
Match: 1a6qA
Description: CRYSTAL STRUCTURE OF THE PROTEIN SERINE/THREONINE PHOSPHATASE 2C AT 2 A RESOLUTION
Matching Structure (courtesy of the PDB):

Predicted Domain #13
Region A:
Residues: [1650-1902] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTTLRRLQPE ISPPTGNLAM VFTDIKSSTF LWELFPNAMR TAIKTHNDIM RRQLRIYGGY  60
   61 EVKTEGDAFM VAFPTPTSGL TWCLSVQLKL LDAQWPEEIT SVQDGCQVTD RNGNIIYQGL 120
  121 SVRMGIHWGC PVPELDLVTQ RMDYLGPMVN KAARVQGVAD GGQIAMSSDF YSEFNKIMKY 180
  181 HERVVKGKES LKEVYGEEII GEVLEREIAM LESIGWAFFD FGEHKLKGLE TKELVTIAYP 240
  241 KILASRHEFA SED

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 310.156545
Match: 1fx4A
Description: Receptor-type monomeric adenylyl cyclase
Matching Structure (courtesy of the PDB):

Predicted Domain #14
Region A:
Residues: [1903-2026] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQSKLINETM LFRLRVISNR LESIMSALSG GFIELDSRTE GSYIKFNPKV ENGIMQSISE  60
   61 KDALLFFDHV ITRIESSVAL LHLRQQRCSG LEICRNDKTS ARSNIFNVVD ELLQMVKNAK 120
  121 DLST

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

    MCM
Score		 SCOP
Match		 SCOP Description
View Download 0.857 a.24.9 alpha-catenin/vinculin

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle