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View Structure Prediction Details

Protein: GTT1
Organism: Saccharomyces cerevisiae
Length: 234 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GTT1.

Description E-value Query
Range
Subject
Range
GSTF_HYOMU - Glutathione S-transferase OS=Hyoscyamus muticus PE=1 SV=1
1.0E-54 [3..225] [1..209]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
4.0E-54 [3..228] [1..212]
gi|8052535 - gi|8052535|gb|AAF71799.1|AC013430_8 F3F9.13 [Arabidopsis thaliana]
5.0E-53 [1..233] [1..208]
gi|34914768, gi|... - gi|34914768|ref|NP_918731.1| putative glutathione S-transferase [Oryza sativa (japonica cultivar-gro...
gi|125525968 - gi|125525968|gb|EAY74082.1| hypothetical protein OsI_01970 [Oryza sativa Indica Group]
9.0E-53 [1..229] [1..213]
gi|14538027, gi|... - gi|5923877|gb|AAD56395.1|AF184059_1 glutathione S-transferase [Triticum aestivum], gi|14538027|gb|AA...
3.0E-52 [1..228] [1..211]
gi|38679413, gi|... - gi|38679413|gb|AAR26528.1| glutathione S-transferase [Glycine max], gi|11385435|gb|AAG34800.1|AF2433...
5.0E-52 [1..233] [1..208]

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Predicted Domain #1
Region A:
Residues: [1-89]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLPIIKVHW LDHSRAFRLL WLLDHLNLEY EIVPYKRDAN FRAPPELKKI HPLGRSPLLE  60
   61 VQDRETGKKK ILAESGFIFQ YVLQHFDHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.09691
Match: 1byeA_
Description: Class phi GST
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
glutathione transferase activity 4.50796867464992 bayes_pls_golite062009
antioxidant activity 3.8464796631544 bayes_pls_golite062009
peroxidase activity 3.44705858438242 bayes_pls_golite062009
oxidoreductase activity, acting on peroxide as acceptor 3.44705858438242 bayes_pls_golite062009
glutathione binding 2.53131331487579 bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors 2.23310780102446 bayes_pls_golite062009
peroxiredoxin activity 2.12777217096121 bayes_pls_golite062009
glutathione peroxidase activity 2.012364779649 bayes_pls_golite062009
thioredoxin peroxidase activity 1.96134566495756 bayes_pls_golite062009
selenium binding 1.67987004910726 bayes_pls_golite062009
protein disulfide oxidoreductase activity 1.47769936616412 bayes_pls_golite062009
disulfide oxidoreductase activity 1.32811008894503 bayes_pls_golite062009
oxidoreductase activity 0.896889139171464 bayes_pls_golite062009
protein disulfide isomerase activity 0.866317336989678 bayes_pls_golite062009
intramolecular oxidoreductase activity, transposing S-S bonds 0.866317336989678 bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH 0.76684639032666 bayes_pls_golite062009
intramolecular oxidoreductase activity, interconverting keto- and enol-groups 0.748123488370707 bayes_pls_golite062009
catalytic activity 0.672192331361968 bayes_pls_golite062009
binding 0.274799360132997 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [90-234]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HVLMSEDADI ADQINYYLFY VEGSLQPPLM IEFILSKVKD SGMPFPISYL ARKVADKISQ  60
   61 AYSSGEVKNQ FDFVEGEISK NNGYLVDGKL SGADILMSFP LQMAFERKFA APEDYPAISK 120
  121 WLKTITSEES YAASKEKARA LGSNF

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.09691
Match: 1byeA_
Description: Class phi GST
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle