YRC Public Data Repository - Protein Structure Prediction

Protein:	YIL167W
Organism:	Saccharomyces cerevisiae
Length:	210 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YIL167W.

Description	E-value	Query Range	Subject Range
gi\|60502212, gi\|... - gi\|60502212\|gb\|AAX22214.1\| threonine deaminase [Nicotiana attenuata], gi\|12539611\|gb\|AAG59585.1\|AF22...	4.0E-46	[2..209]	[230..421]
TRPB1_PYRAB - Tryptophan synthase beta chain 1 OS=Pyrococcus abyssi (strain GE5 / Orsay) GN=trpB1 PE=3 SV=1 TRPB1_PYRAB, TRB... - Tryptophan synthase beta chain 1 OS=Pyrococcus abyssi GN=trpB1 PE=3 SV=1, (Q9V1G8) Tryptophan syntha...	2.0E-43	[14..203]	[189..384]
gi\|146452 - gi\|146452\|gb\|AAA24014.1\| threonine dehydratase [Escherichia coli]	3.0E-43	[2..198]	[142..328]
TRPB1_PYRFU - Tryptophan synthase beta chain 1 OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / V... TRPB1_PYRFU, TRB... - Tryptophan synthase beta chain 1 OS=Pyrococcus furiosus GN=trpB1 PE=1 SV=1, (Q8U093) Tryptophan synt...	3.0E-43	[14..203]	[189..384]
gi\|11352638 - pir\|\|B83479 threonine dehydratase, biosynthetic PA1326 [imported] - Pseudomonas aeruginosa (strain P... gi\|116049278, gi... - gi\|32041368\|ref\|ZP_00138951.1\| COG1171: Threonine dehydratase [Pseudomonas aeruginosa UCBPP-PA14], g... gi\|15596523, gi\|... - gi\|9947265\|gb\|AAG04715.1\|AE004562_2 threonine dehydratase, biosynthetic [Pseudomonas aeruginosa PAO1... gi\|194545433, gi... - gi\|84321937\|ref\|ZP_00970288.1\| COG1171: Threonine dehydratase [Pseudomonas aeruginosa C3719], gi\|254... gi\|254239698, gi... - gi\|84328262\|ref\|ZP_00976269.1\| COG1171: Threonine dehydratase [Pseudomonas aeruginosa 2192], gi\|2542... gi\|218772797, gi... - gi\|218892569\|ref\|YP_002441438.1\| threonine dehydratase [Pseudomonas aeruginosa LESB58], gi\|218772797...	4.0E-43	[2..209]	[142..334]
TRPB_HELPJ - Tryptophan synthase beta chain OS=Helicobacter pylori (strain J99 / ATCC 700824) GN=trpB PE=3 SV=1 gi\|7437012 - gi\|7437012\|pir\|\|C71836 tryptophan synthase beta chain - Helicobacter pylori (strain J99)	4.0E-43	[14..206]	[192..390]
TRPB_CAMAC - Tryptophan synthase beta chain 2, chloroplastic OS=Camptotheca acuminata GN=TSB PE=2 SV=1	5.0E-43	[14..204]	[268..464]
TRPB_HELPY - Tryptophan synthase beta chain OS=Helicobacter pylori (strain ATCC 700392 / 26695) GN=trpB PE=3 SV=1 TRPB_HELPY - Tryptophan synthase beta chain OS=Helicobacter pylori GN=trpB PE=3 SV=1	7.0E-43	[14..206]	[192..390]
TRBP2_ARATH - Tryptophan synthase beta chain 2, chloroplastic OS=Arabidopsis thaliana GN=TSB2 PE=1 SV=2	2.0E-42	[14..205]	[277..474]

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Predicted Domain #1

Region A:
Residues: [1-210]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAQESQHGSK TLYVHPFDNE TIWEGHSTIV DEIIEQLKEN DISLPRVKAL VCSVGGGGLF  60
   61 SGIIKGLDRN QLAEKIPVVA VETAGCDVLN KSLKKGSPVT LEKLTSVATS LASPYIASFA 120
  121 FESFNKYGCK SVVLSDQDVL ATCLRYADDY NFIVEPACGA SLHLCYHPEI LEDILEQKIY 180
  181 EDDIVIIIAC GGSCMTYEDL VKASSTLNVS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	81.533179
Match:	1tdj__
Description:	Allosteric threonine deaminase N-terminal domain; Allosteric threonine deaminase C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	1.85988364660567	bayes_pls_golite062009
lyase activity	0.92121242786289	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: