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View Structure Prediction Details

Protein: ESL1
Organism: Saccharomyces cerevisiae
Length: 1118 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ESL1.

Description E-value Query
Range
Subject
Range
ESL1 - Putative protein of unknown function, predicted to contain a PINc domain
ESL1_YEAST - EST/SMG-like protein 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ESL1 PE=1 SV=1
0.0 [1..1118] [1..1118]

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Predicted Domain #1
Region A:
Residues: [1-943]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVDLMVPAND DPSNETDYSR SNNNHTHIVS DMRPTSAAFL HQKRHSSSSH NDTPESSFAK  60
   61 RRVPGIVDPV GKGFIDGITN SQISAQNTPS KTDDASRRPS ISRKVMESTP QVKTSSIPTM 120
  121 DVPKSPYYVN RTMLARNMKV VSRDTYEDNA NPQMRADEPL VASNGIYSNS QPQSQVTLSD 180
  181 IRRAPVVAAS PPPMIRQLPS AQPNQTFIKK LQEIYKIIVV QETELQQRCL YLTTSQTTEL 240
  241 KSLWAIYRLN TELIKNYINF IITALLTTQP INDLIMGQEI LDIYRIEKRL WVYGIITFLD 300
  301 VLKNFSNFMD PEVCCQFIIY AFISVSNMLE DIPLKYSILW RQRLGDLSRM AISLYPSGFI 360
  361 DWRLSAEYWY TESMKYIYGC GKLYYHIATV QQNSLEAFVN LGKSVFCQDP FTPSQQTLQL 420
  421 LIENIYQSAF IDRSSGSANN NEIAHRNSQL IDYLKHTEVM LLPSFLENMD LQHVVLMYFK 480
  481 DKFGKDFNGN DVFDTKDMFC QNPESLRYYF RHAPAFAESQ LLQLIGFGNP KNPFALLFQL 540
  541 PKYLKLKKDK REKKRSEATE TSSYTDPFDV QISSESYFQN IDALNSSFND IPTNLNIWLD 600
  601 SLNHINMTSI QCSIHVLTKF LHAPLVVALP HFLTWLHFIV AILKKLEMVN SKQVVAFWIH 660
  661 FLRRTMPWNS IVTLGNVLVC YMLDNLHPFL KKELEKFYSL ELDDLIEYYN ENENLPEIWK 720
  721 CWGTLWFDAI KKCDVMEIPG VQDHLFFDSP LDGIVFDEKD EVGEKFWMRS VRAVLLLKGI 780
  781 AKKFPDLGLK VSFQASVFCR RNDIPPDYFL KNLTFKLDAY DEDNYNDNNE LDDLYDTIEI 840
  841 NEEIEAVNMD PQATPNLSVV SGESIFEYTG YTRLAPDYHC FDKNGGFNSA FIYSQWSNVG 900
  901 NGVTLDVSGE SIYDVANNNL SLHWEKIFFD KIAAASKGSD ENY

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [944-1118]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NCTLYFVIDA TSWLRHFAHI FKLAKNNTLK FAICLTTFQE LRYLRGSKDD TVVEAATRSV  60
   61 ITIRQLYDEK KIIPMRFTGN IATHVEENLE FEEQITWKTH VDEFVIDAIA KLNQRFQAER 120
  121 LTDENKNKGK EFAVLVTDDD NMNQKAKDRM IKTCNTKYLF SLGSKLGINS GLCTN

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term Confidence Notes
protein binding 1.39469381877563 bayes_pls_golite062009
binding 1.15429718277387 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [819-899]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AYDEDNYNDN NELDDLYDTI EINEEIEAVN MDPQATPNLS VVSGESIFEY TGYTRLAPDY  60
   61 HCFDKNGGFN SAFIYSQWSN V

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [900-1118]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GNGVTLDVSG ESIYDVANNN LSLHWEKIFF DKIAAASKGS DENYNCTLYF VIDATSWLRH  60
   61 FAHIFKLAKN NTLKFAICLT TFQELRYLRG SKDDTVVEAA TRSVITIRQL YDEKKIIPMR 120
  121 FTGNIATHVE ENLEFEEQIT WKTHVDEFVI DAIAKLNQRF QAERLTDENK NKGKEFAVLV 180
  181 TDDDNMNQKA KDRMIKTCNT KYLFSLGSKL GINSGLCTN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 4.18
Match: 2dokA
Description: No description for 2dokA was found.

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle