YRC Public Data Repository - Protein Structure Prediction

Protein:	TPM2
Organism:	Saccharomyces cerevisiae
Length:	161 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TPM2.

Description	E-value	Query Range	Subject Range
gi\|37403, gi\|224906 - gi\|37403\|emb\|CAA27243.1\| unnamed protein product [Homo sapiens], gi\|224906\|prf\|\|1203383A gene oncD	5.0E-39	[2..161]	[8..171]
gi\|542160194\|ref... - PREDICTED: tropomyosin beta chain isoform X1 [Zonotrichia albicollis] TPM2_CHICK - Tropomyosin beta chain OS=Gallus gallus GN=TPM2 PE=1 SV=1	1.0E-24	[4..161]	[46..207]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-24	[4..161]	[46..207]
TPM1_RANTE - Tropomyosin alpha-1 chain OS=Rana temporaria GN=tpm1 PE=2 SV=1	2.0E-24	[3..161]	[45..207]

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Predicted Domain #1

Region A:
Residues: [1-91]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKIKEKLNS LKLESESWQE KYEELREQLK ELEQSNTEKE NEIKSLSAKN EQLDSEVEKL  60
   61 ESQLSDTKQL AEDSNNLRSN NENYTKKNQD L

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.29073
Match:	2tmaA_
Description:	Tropomyosin
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [92-161]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQQLEDSEAK LKEAMDKLKE ADLNSEQMGR RIVALEEERD EWEKKCEEFQ SKYEEAQKEL  60
   61 DEIANSLENL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.29073
Match:	2tmaA_
Description:	Tropomyosin
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits