YRC Public Data Repository - Protein Structure Prediction

Protein:	RPN2
Organism:	Saccharomyces cerevisiae
Length:	945 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RPN2.

Description	E-value	Query Range	Subject Range
gi\|172578 - gi\|172578\|gb\|AAA87613.1\| SEN3 [Saccharomyces cerevisiae]	906.0	[0..1]	[945..1]
gi\|76610889 - gi\|76610889\|ref\|XP_886237.1\| PREDICTED: similar to proteasome 26S non-ATPase subunit 1 isoform 16 [B...	841.0	[0..3]	[926..2]
gi\|109101399 - gi\|109101399\|ref\|XP_001113035.1\| PREDICTED: similar to proteasome 26S non-ATPase subunit 1 [Macaca m...	833.0	[0..3]	[926..2]
gi\|55732382 - gi\|55732382\|emb\|CAH92892.1\| hypothetical protein [Pongo abelii] PSMD1_PONAB - 26S proteasome non-ATPase regulatory subunit 1 OS=Pongo abelii GN=PSMD1 PE=2 SV=1 ENSPTRT00000024140 - null	833.0	[0..3]	[926..2]
PSD, PSMD1 - proteasome (prosome, macropain) 26S subunit, non-ATPase, 1, pleckstrin and Sec7 domain containing	832.0	[0..3]	[926..2]
PSMD1_MOUSE - 26S proteasome non-ATPase regulatory subunit 1 OS=Mus musculus GN=Psmd1 PE=1 SV=1	831.0	[0..3]	[926..2]
PSMD1_RAT - 26S proteasome non-ATPase regulatory subunit 1 OS=Rattus norvegicus GN=Psmd1 PE=1 SV=1	830.0	[0..3]	[926..2]

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Predicted Domain #1

Region A:
Residues: [1-148]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLTTAAPLL ALLRENQDSV KTYALESINN VVDQLWSEIS NELPDIEALY DDDTFSDREM  60
   61 AALIASKVYY NLGEYESAVK YALAAKDRFD IDEKSQFVET IVSKSIEMYV QEASKQYTKD 120
  121 EQFYTKDIID PKLTSIFERM IEKCLKAS

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	8.22
Match:
Description:	No description for 1b3uA was found.

Predicted Domain #2

Region A:
Residues: [149-235]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELKLALGIAL EGYRLDIIES ALKSKLDQDS TSENVKIINY LLTLAITTVT NSKFRSSILR  60
   61 KSFDFLMNMP NCDYLTLNKV VVNLNDA

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	8.22
Match:
Description:	No description for 1b3uA was found.

Predicted Domain #3

Region A:
Residues: [236-360]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLALQLFKKL KEENDEGLSA QIAFDLVSSA SQQLLEILVT ELTAQGYDPA LLNILSGLPT  60
   61 CDYYNTFLLN NKNIDIGLLN KSKSSLDGKF SLFHTAVSVA NGFMHAGTTD NSFIKANLPW 120
  121 LGKAQ

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	8.22
Match:
Description:	No description for 1b3uA was found.

Predicted Domain #4

Region A:
Residues: [361-560]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NWAKFTATAS LGVIHKGNLL EGKKVMAPYL PGSRASSRFI KGGSLYGLGL IYAGFGRDTT  60
   61 DYLKNIIVEN SGTSGDEDVD VLLHGASLGI GLAAMGSANI EVYEALKEVL YNDSATSGEA 120
  121 AALGMGLCML GTGKPEAIHD MFTYSQETQH GNITRGLAVG LALINYGRQE LADDLITKML 180
  181 ASDESLLRYG GAFTIALAYA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.221849
Match:	1b3uA
Description:	Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #5

Region A:
Residues: [561-721]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTGNNSAVKR LLHVAVSDSN DDVRRAAVIA LGFVLLRDYT TVPRIVQLLS KSHNAHVRCG  60
   61 TAFALGIACA GKGLQSAIDV LDPLTKDPVD FVRQAAMIAL SMILIQQTEK LNPQVADINK 120
  121 NFLSVITNKH QEGLAKFGAC VAQGIMNAGG RNVTIQLENA D

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.221849
Match:	1b3uA
Description:	Constant regulatory domain of protein phosphatase 2a, pr65alpha
Matching Structure (courtesy of the PDB):

Predicted Domain #6

Region A:
Residues: [722-801]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TGTLDTKSVV GLVMFSQFWY WFPLAHFLSL SFTPTTVIGI RGSDQAIPKF QMNCYAKEDA  60
   61 FSYPRMYEEA SGKEVEKVAT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.0
Match:	1jmmA
Description:	V-region of surface antigen I/II (SA I/II, PAC)
Matching Structure (courtesy of the PDB):

Predicted Domain #7

Region A:
Residues: [802-945]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AVLSTTARAK ARAKKTKKEK GPNEEEKKKE HEEKEKERET NKKGIKETKE NDEEFYKNKY  60
   61 SSKPYKVDNM TRILPQQSRY ISFIKDDRFV PVRKFKGNNG VVVLRDREPK EPVALIETVR 120
  121 QMKDVNAPLP TPFKVDDNVD FPSA

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits