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View Structure Prediction Details

Protein: NEO1
Organism: Saccharomyces cerevisiae
Length: 1151 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NEO1.

Description E-value Query
Range		 Subject
Range
gi|207344311 - gi|207344311|gb|EDZ71498.1| YIL048Wp-like protein [Saccharomyces cerevisiae AWRI1631]
NEO1 - Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; l...
gi|190406268 - gi|190406268|gb|EDV09535.1| P-type ATPase [Saccharomyces cerevisiae RM11-1a]
ATC7_YEAST - Probable phospholipid-transporting ATPase NEO1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S28...
gi|151943111 - gi|151943111|gb|EDN61446.1| neomycin-resistance protein [Saccharomyces cerevisiae YJM789]
 0.0 [1..1151] [1..1151]
AT1A1_HORSE - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Equus caballus GN=ATP1A1 PE=3 SV=1
 0.0 [102..1144] [5..1017]
gi|447739 - gi|447739|prf||1915304A nylB upstream ORF
 0.0 [117..1144] [15..1011]
AT1A2_CHICK - Sodium/potassium-transporting ATPase subunit alpha-2 OS=Gallus gallus GN=ATP1A2 PE=2 SV=1
 0.0 [117..1144] [17..1013]
AT1A1_SHEEP - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Ovis aries GN=ATP1A1 PE=1 SV=1
 0.0 [103..1144] [6..1017]
SPBC887.12 - P-type ATPase
YOOC_SCHPO - Probable phospholipid-transporting ATPase C887.12 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24...
 0.0 [30..1150] [36..1197]
gi|89248 - pir||B24862 Na+/K+-exchanging ATPase (EC 3.6.3.9) alpha chain - pig
AT1A1_PIG - Sodium/potassium-transporting ATPase subunit alpha-1 OS=Sus scrofa GN=ATP1A1 PE=1 SV=1
 0.0 [103..1144] [6..1017]

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Predicted Domain #1
Region A:
Residues: [1-114] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPNPPSFKSH KQNLFNSNNN QHANSVDSFD LHLDDSFDAA LDSLQINNNP EPLSKHNTVG  60
   61 DRESFEMRTV DDLDNFSNHS SDSHRKSSNT DTHPLMYDNR LSQDDNFKFT NIAS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [115-177] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SPPSSSNNIF SKALSYLKVS NTKNWSKFGS PIELSDQHIE REIHPDTTPV YDRNRYVSNE  60
   61 LSN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [254-356] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ELYHVITRNR SIPSKDLKVG DLIKVHKGDR IPADLVLLQS SEPSGESFIK TDQLDGETDW  60
   61 KLRVACPLTQ NLSENDLINR ISITASAPEK SIHKFLGKVT YKD

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1072.218487
Match: 1eulA_
Description: Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #3
Region A:
Residues: [178-246] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AKYNAVTFVP TLLYEQFKFF YNLYFLVVAL SQAVPALRIG YLSSYIVPLA FVLTVTMAKE  60
   61 AIDDIQRRR

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [357-466] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STSNPLSVDN TLWANTVLAS SGFCIACVVY TGRDTRQAMN TTTAKVKTGL LELEINSISK  60
   61 ILCACVFALS ILLVAFAGFH NDDWYIDILR YLILFSTIIP VSLRVNLDLA

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [932-1151] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SYKRSAKLAQ FVMHRGLIIA ICQAVYSICS LFEPIALYQG WLMVGYATCY TMAPVFSLTL  60
   61 DHDIEESLTK IYPELYKELT EGKSLSYKTF FVWVLLSLFQ GSVIQLFSQA FTSLLDTDFT 120
  121 RMVAISFTAL VVNELIMVAL EIYTWNKTML VTEIATLLFY IVSVPFLGDY FDLGYMTTVN 180
  181 YYAGLLVILL ISIFPVWTAK AIYRRLHPPS YAKVQEFATP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1072.218487
Match: 1eulA_
Description: Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #4
Region A:
Residues: [247-253] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDRESNN

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [467-510] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KSVYAHQIEH DKTIPETIVR TSTIPEDLGR IEYLLSDKTG TLTQ

[Run NCBI BLAST on this sequence.]

Region C:
Residues: [752-931] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQKDVKSSIE LLRNAGIKIW MLTGDKVETA RCVSISAKLI SRGQYVHTIT KVTRPEGAFN  60
   61 QLEYLKINRN ACLLIDGESL GMFLKHYEQE FFDVVVHLPT VIACRCTPQQ KADVALVIRK 120
  121 MTGKRVCCIG DGGNDVSMIQ CADVGVGIVG KEGKQASLAA DFSITQFCHL TELLLWHGRN 180
  181

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1072.218487
Match: 1eulA_
Description: Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M

Predicted Domain #5
Region A:
Residues: [511-751] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDMQLKKIHL GTVSYTSETL DIVSDYVQSL VSSKNDSLNN SKVALSTTRK DMSFRVRDMI  60
   61 LTLAICHNVT PTFEDDELTY QAASPDEIAI VKFTESVGLS LFKRDRHSIS LLHEHSGKTL 120
  121 NYEILQVFPF NSDSKRMGII VRDEQLDEYW FMQKGADTVM SKIVESNDWL EEETGNMARE 180
  181 GLRTLVIGRK KLNKKIYEQF QKEYNDASLS MLNRDQQMSQ VITKYLEHDL ELLGLTGVED 240
  241 K

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 1072.218487
Match: 1eulA_
Description: Calcium ATPase, transduction domain A; Calcium ATPase, catalytic domain P; Calcium ATPase; Calcium ATPase, transmembrane domain M
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle