YRC Public Data Repository - Protein Structure Prediction

Protein:	TED1
Organism:	Saccharomyces cerevisiae
Length:	473 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TED1.

Description	E-value	Query Range	Subject Range
TED1_YEAST - Protein TED1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TED1 PE=1 SV=1 TED1 - Conserved phosphoesterase domain-containing protein that acts together with Emp24p/Erv25p in cargo e...	0.0	[1..473]	[1..473]
MPPE1_MACFA - Metallophosphoesterase 1 OS=Macaca fascicularis GN=MPPE1 PE=2 SV=1	8.0E-93	[116..468]	[59..374]
gi\|4063002, gi\|2... - gi\|4063002\|dbj\|BAA36220.1\| fr [Neurospora crassa], gi\|32414579\|ref\|XP_327769.1\| hypothetical protein... gi\|85116321 - gi\|85116321\|ref\|XP_965030.1\| hypothetical protein ( (AB021703) fr [Neurospora crassa OR74A] )	8.0E-86	[85..473]	[127..558]
gi\|18027324, gi\|... - ref\|NP_613074.1\| metallophosphoesterase 1 [Homo sapiens], gi\|18027324\|gb\|AAL55744.1\|AF289560_1 unkn...	2.0E-80	[117..416]	[60..340]
SPAC630.12 - phosphoprotein phosphatase YKIC_SCHPO - Uncharacterized protein C630.12 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC630.12...	2.0E-75	[114..472]	[34..364]
gi\|25501285 - pir\|\|H96924 probable phosphohydrolases, Icc family [imported] - Clostridium acetobutylicum gi\|15893498, gi\|... - gi\|15893498\|ref\|NP_346847.1\| Icc family phosphohydrolase [Clostridium acetobutylicum ATCC 824], gi\|1...	2.0E-67	[61..422]	[64..398]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	3.0E-65	[82..453]	[53..374]

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Predicted Domain #1

Region A:
Residues: [1-175]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLRCAVKKFA YFATFLTIVA NIYIYTYPSF HPEQCSWNCS NKNAPLQKDL TFVDKVKNYF  60
   61 SDVREQWHGS HASAGNDEDI HILAFGDPQI KGIWPKTPYV SRLDTYGNDY YLGHIYDMMQ 120
  121 QRLKPQVVTV MGDLFSSQWI GDSEFHNRTK RYISRIFKRD PTSIENIKQQ NLDEK

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [176-473]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GQYKANWPEW GDRFNEILDN VKENEADNQE LSFGFGYENI HSWNPDLEDF LIINITGNHD  60
   61 VGYSGDATYQ HMTRFHDLFG KDNYWIEYET NTTHPWRIVV LNDLLLEGPA LQPEFVEATW 120
  121 IFLNQLNERK FNGSTVLLTH VPFYKREGLC VDGPDTRYYP DAHAPESYKS GLLRSQNHLS 180
  181 ESVSNQVLNM IFENGKPGII LTGHDHEGCE TVYNKKSTST WEATKNIESD VFVKEITVKS 240
  241 MMGEFNGNTG LVTGHFNTDS MTWEWTFSLC PFAIQHVWWF AKVSLLVTIF TWSSLLFV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.39794
Match:	1qfcA_
Description:	Mammalian purple acid phosphatase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits