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View Structure Prediction Details

Protein: CST6
Organism: Saccharomyces cerevisiae
Length: 587 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CST6.

Description E-value Query
Range
Subject
Range
gi|114581857 - gi|114581857|ref|XP_001152057.1| PREDICTED: chimerin (chimaerin) 1 isoform 6 [Pan troglodytes]
243.0 [0..171] [507..96]
gi|840708 - gi|840708|dbj|BAA09334.1| trans-sialidase [Trypanosoma cruzi]
197.0 [0..7] [389..682]
gi|70869911 - gi|70869911|gb|EAN84377.1| trans-sialidase, putative [Trypanosoma cruzi]
gi|71407532 - gi|71407532|ref|XP_806228.1| trans-sialidase [Trypanosoma cruzi strain CL Brener]
190.0 [0..7] [418..670]
gi|67970401 - gi|67970401|dbj|BAE01543.1| unnamed protein product [Macaca fascicularis]
184.0 [0..162] [544..89]
ACA1 - Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription ...
ACA1_YEAST - ATF/CREB activator 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ACA1 PE=2 SV=1
183.0 [0..127] [531..81]
gi|76609561, gi|... - gi|76609561|ref|XP_881017.1| PREDICTED: similar to activating transcription factor 2 isoform 11 [Bos...
182.0 [0..162] [544..89]

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Predicted Domain #1
Region A:
Residues: [1-300]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MFTGQEYHSV DSNSNKQKDN NKRGIDDTSK ILNNKIPHSV SDTSAAATTT STMNNSALSR  60
   61 SLDPTDINYS TNMAGVVDQI HDYTTSNRNS LTPQYSIAAG NVNSHDRVVK PSANSNYQQA 120
  121 AYLRQQQQQD QRQQSPSMKT EEESQLYGDI LMNSGVVQDM HQNLATHTNL SQLSSTRKSA 180
  181 PNDSTTAPTN ASNIANTASV NKQMYFMNMN MNNNPHALND PSILETLSPF FQPFGVDVAH 240
  241 LPMTNPPIFQ SSLPGCDEPI RRRRISISNG QISQLGEDIE TLENLHNTQP PPMPNFHNYN 300
  301 

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [301-379]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GLSQTRNVSN KPVFNQAVPV SSIPQYNAKK VINPTKDSAL GDQSVIYSKS QQRNFVNAPS  60
   61 KNTPAESISD LEGMTTFAP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.583 a.4.5 "Winged helix" DNA-binding domain
View Download 0.487 a.4.1 Homeodomain-like
View Download 0.430 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.430 a.4.6 C-terminal effector domain of the bipartite response regulators
View Download 0.381 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.370 a.4.5 "Winged helix" DNA-binding domain
View Download 0.298 d.39.1 Dynein light chain 8 (DLC8)
View Download 0.275 a.156.1 S13-like H2TH domain

Predicted Domain #3
Region A:
Residues: [380-504]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TTGGENRGKS ALRESHSNPS FTPKSQGSHL NLAANTQGNP IPGTTAWKRA RLLERNRIAA  60
   61 SKCRQRKKVA QLQLQKEFNE IKDENRILLK KLNYYEKLIS KFKKFSKIHL REHEKLNKDS 120
  121 DNNVN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 21.522879
Match: 1gtwA
Description: CRYSTAL STRUCTURE OF C/EBPBETA BZIP HOMODIMER BOUND TO A DNA FRAGMENT FROM THE TOM-1A PROMOTER
Matching Structure (courtesy of the PDB):

Predicted Domain #4
Region A:
Residues: [505-587]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GTNSSNKNES MTVDSLKIIE ELLMIDSDVT EVDKDTGKII AIKHEPYSQR FGSDTDDDDI  60
   61 DLKPVEGGKD PDNQSLPNSE KIK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.461 a.77.1 DEATH domain
View Download 0.461 a.77.1 DEATH domain
View Download 0.352 a.77.1 DEATH domain
View Download 0.296 a.77.1 DEATH domain
View Download 0.296 a.77.1 DEATH domain
View Download 0.266 a.77.1 DEATH domain
View Download 0.260 d.58.11 EF-G/eEF-2 domains III and V
View Download 0.233 a.35.1 lambda repressor-like DNA-binding domains
View Download 0.202 a.163.1 Crustacean CHH/MIH/GIH neurohormone


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle