YRC Public Data Repository - Protein Structure Prediction

Protein:	TIR3
Organism:	Saccharomyces cerevisiae
Length:	269 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TIR3.

Description	E-value	Query Range	Subject Range
gi\|840706 - gi\|840706\|dbj\|BAA09333.1\| trans-sialidase [Trypanosoma cruzi]	3.0E-42	[35..251]	[667..889]
CE12954 - WBGene00011326 EGF-like domains status:Partially_confirmed TR:O01335 protein_id:CAB03261.1	4.0E-41	[9..242]	[2942..3172]
gi\|15828996 - gi\|15828996\|ref\|NP_326356.1\| lipoprotein VSAC (fragment) [Mycoplasma pulmonis UAB CTIP] gi\|14089939, gi\|... - pir\|\|E90577 lipoprotein vsaC [imported] - Mycoplasma pulmonis (strain UAB CTIP) (fragment), gi\|14089...	3.0E-28	[11..245]	[110..350]
PKN6_MYXXA - Serine/threonine-protein kinase pkn6 OS=Myxococcus xanthus GN=pkn6 PE=2 SV=1 gi\|108464787, gi... - gi\|108760907\|ref\|YP_630769.1\| serine/threonine protein kinase Pkn6 [Myxococcus xanthus DK 1622], gi\|...	2.0E-27	[61..262]	[301..492]
gi\|9695347 - gi\|9695347\|gb\|AAF97432.1\|U23947_9 VsaC1 [Mycoplasma pulmonis]	6.0E-26	[11..245]	[277..517]
gi\|25530707 - pir\|\|AC2098 hypothetical protein alr2338 [imported] - Nostoc sp. (strain PCC 7120) gi\|17229830, gi\|... - gi\|17229830\|ref\|NP_486378.1\| hypothetical protein alr2338 [Nostoc sp. PCC 7120], gi\|17131430\|dbj\|BAB...	5.0E-24	[8..212]	[195..389]

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Predicted Domain #1

Region A:
Residues: [1-110]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFTKIAALL AVAAASTQLV SAEVGQYEIV EFDAILADVK ANLEQYMSLA MNNPDFTLPS  60
   61 GVLDVYQHMT TATDDSYTSY FTEMDFAQIT TAMVQVPWYS SRLEPEIIAA

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	63.49485
Match:	PF00660
Description:	Seripauperin and TIP1 family

Shown below is our most confident prediction for this domain.
Click here to view all matches.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.925	N/A	N/A	a.7.3	Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain

Predicted Domain #2

Region A:
Residues: [111-269]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LQSAGISITS LGQTVSESGS ESATASSDAS SASESSSAAS SSASESSSAA SSSASESSSA  60
   61 ASSSASESSS AASSSASEAA KSSSSAKSSG SSAASSAASS ASSKASSAAS SSAKASSSAE 120
  121 KSTNSSSSAT SKNAGAAMDM GFFSAGVGAA IAGAAAMLL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	3.69897
Match:	1deqA_
Description:	Fibrinogen
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits