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View Structure Prediction Details

Protein: MTC6
Organism: Saccharomyces cerevisiae
Length: 526 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTC6.

Description E-value Query
Range
Subject
Range
MTC6_YEAST - Maintenance of telomere capping protein 6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) G...
MTC6_YEAS7 - Maintenance of telomere capping protein 6 OS=Saccharomyces cerevisiae (strain YJM789) GN=MTC6 PE=3 S...
MTC6 - Protein of unknown function; mtc6 is synthetically sick with cdc13-1
0.0 [1..526] [1..526]

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Predicted Domain #1
Region A:
Residues: [1-526]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MWILIYLFII WSSLRTWVTA VDSTTTVGDD LNETVSASVW PTMSPQMTVA FRSQRDVMGN  60
   61 LTIDQLPYVG LNLRRVLLNN ETSMVNEGNN TRLLTLFKSM LSSEANAFVL DLEQYNNDLR 120
  121 VVDTTLLFSD VLTALQSFIF STQNNLYANI IVLLLNISAP ELDSTEYRHQ NQTLNTTYIL 180
  181 DKNLGNSFIY KPTDLQSDRA KNNTWNIYGK SSIDGWPTLG SVLYEQKKRL VIGELTDFFN 240
  241 ETTAPYIFPH DVFHYEQGNS TLDCPSTVEG LTDLSSIHWR FLDSLFNSVD IKEYISCGLS 300
  301 PIISNSAYVN NVTQLADIIH EGSVWSWDSD QPSVTQSTSK SGSSSGTLEA YNCVLLYYFA 360
  361 NNETVTWRVG NCYNSNIGLC RYENMAFRWL VRSNKATYFD FDSYQGSKCP DQYSFNIPRS 420
  421 PLEQRSFIAY MRNSSFSDTQ IWIDLNSISV SNCWVSGGPY ASCPYEKVIS RRNFVTMMVP 480
  481 ASVCSFALLC IVVYLSVLRV PIYDNRKNWR RVINKISKSE LEGVPS

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [289-526]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VDIKEYISCG LSPIISNSAY VNNVTQLADI IHEGSVWSWD SDQPSVTQST SKSGSSSGTL  60
   61 EAYNCVLLYY FANNETVTWR VGNCYNSNIG LCRYENMAFR WLVRSNKATY FDFDSYQGSK 120
  121 CPDQYSFNIP RSPLEQRSFI AYMRNSSFSD TQIWIDLNSI SVSNCWVSGG PYASCPYEKV 180
  181 ISRRNFVTMM VPASVCSFAL LCIVVYLSVL RVPIYDNRKN WRRVINKISK SELEGVPS

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.05
Match: 1htnA
Description: HUMAN TETRANECTIN, A TRIMERIC PLASMINOGEN BINDING PROTEIN WITH AN ALPHA-HELICAL COILED COIL
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.327824947914988 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle