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View Structure Prediction Details

Protein: EPT1
Organism: Saccharomyces cerevisiae
Length: 391 amino acids
Reference: Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EPT1.

Description E-value Query
Range
Subject
Range
gi|190405902 - gi|190405902|gb|EDV09169.1| sn-1,2-diacylglycerol ethanolamine [Saccharomyces cerevisiae RM11-1a]
EPT1_YEAST - Choline/ethanolaminephosphotransferase 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...
EPT1 - sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability
0.0 [1..391] [1..391]
AAPT1_ARATH - Choline/ethanolaminephosphotransferase 1 OS=Arabidopsis thaliana GN=AAPT1 PE=1 SV=1
2.0E-97 [1..389] [1..388]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
2.0E-96 [1..389] [1..388]
gi|5917787 - gi|5917787|gb|AAD56040.1|AF183933_1 aminoalcoholphosphotransferase [Brassica rapa]
8.0E-95 [1..389] [1..388]
CCDS830.1_1 - null
CEPT1 - choline/ethanolamine phosphotransferase 1
gi|114558962, gi... - gi|114558966|ref|XP_001161701.1| PREDICTED: choline/ethanolaminephosphotransferase isoform 7 [Pan tr...
7.0E-94 [4..388] [42..409]
gi|3927806 - gi|3927806|gb|AAC79507.1| aminoalcoholphosphotransferase [Pimpinella brachycarpa]
2.0E-93 [1..389] [1..388]

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Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGYFVPDSHI ENLKSYKYQS EDRSLVSKYF LKPFWQRFCH IFPTWMAPNI ITLSGFAFIV  60
   61 INVLTVFYYD PNLNT

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.479 a.71.2 Helical domain of Sec23/24
View Download 0.564 a.4.1 Homeodomain-like
View Download 0.460 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.724 a.156.1 S13-like H2TH domain
View Download 0.558 a.64.1 Saposin
View Download 0.785 a.7.7 BAG domain
View Download 0.424 a.47.2 t-snare proteins
View Download 0.489 a.144.1 PABC (PABP) domain
View Download 0.573 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.473 a.17.1 p8-MTCP1
View Download 0.558 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.489 a.144.1 PABC (PABP) domain
View Download 0.483 a.2.11 Fe,Mn superoxide dismutase (SOD), N-terminal domain
View Download 0.479 a.71.2 Helical domain of Sec23/24
View Download 0.473 a.17.1 p8-MTCP1
View Download 0.468 a.112.1 Description not found.
View Download 0.460 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.458 a.101.1 Uteroglobin-like
View Download 0.456 a.64.2 Bacteriocin AS-48
View Download 0.451 d.95.2 Homing endonucleases
View Download 0.439 a.4.1 Homeodomain-like
View Download 0.432 a.156.1 S13-like H2TH domain
View Download 0.431 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.427 f.14.1 Voltage-gated potassium channels
View Download 0.424 a.47.2 t-snare proteins
View Download 0.416 a.156.1 S13-like H2TH domain
View Download 0.383 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.377 a.58.1 Chemotaxis receptor methyltransferase CheR, N-terminal domain
View Download 0.374 a.177.1 Sigma2 domain of RNA polymerase sigma factors
View Download 0.370 d.87.2 CO dehydrogenase flavoprotein C-terminal domain-like
View Download 0.369 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.363 c.9.1 Barstar (barnase inhibitor)
View Download 0.358 d.51.1 Eukaryotic type KH-domain (KH-domain type I)
View Download 0.358 d.56.1 GroEL-intermediate domain like
View Download 0.352 a.50.1 Anaphylotoxins (complement system)
View Download 0.350 a.130.1 Chorismate mutase II
View Download 0.338 a.27.1 Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View Download 0.337 a.24.3 Cytochromes
View Download 0.336 d.96.1 Tetrahydrobiopterin biosynthesis enzymes-like
View Download 0.335 d.202.1 Transcription factor NusA, N-terminal domain
View Download 0.331 a.7.6 Ribosomal protein S20
View Download 0.329 a.64.2 Bacteriocin AS-48
View Download 0.327 a.112.1 Description not found.
View Download 0.323 a.4.5 "Winged helix" DNA-binding domain
View Download 0.319 a.46.1 Methionine synthase domain
View Download 0.318 a.5.6 Hypothetical protein MTH1615
View Download 0.309 a.151.1 Glutamyl tRNA-reductase dimerization domain
View Download 0.307 a.38.1 Helix-loop-helix DNA-binding domain
View Download 0.306 d.58.17 Metal-binding domain
View Download 0.301 a.24.13 Domain of the SRP/SRP receptor G-proteins
View Download 0.300 a.2.7 tRNA-binding arm
View Download 0.299 a.30.2 Homodimeric domain of signal transducing histidine kinase
View Download 0.298 a.64.1 Saposin
View Download 0.296 a.2.6 Effector domain of the protein kinase pkn/prk1
View Download 0.295 a.133.1 Phospholipase A2, PLA2
View Download 0.285 a.54.1 Domain of early E2A DNA-binding protein, ADDBP
View Download 0.284 a.39.1 EF-hand
View Download 0.284 a.4.11 RNA polymerase subunit RPB10
View Download 0.277 d.58.7 RNA-binding domain, RBD
View Download 0.275 a.11.1 Acyl-CoA binding protein
View Download 0.275 a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.273 a.4.5 "Winged helix" DNA-binding domain
View Download 0.272 a.7.3 Succinate dehydrogenase/fumarate reductase flavoprotein C-terminal domain
View Download 0.263 a.13.1 alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View Download 0.263 a.29.2 Bromodomain
View Download 0.261 a.7.7 BAG domain
View Download 0.260 a.144.1 PABC (PABP) domain
View Download 0.255 a.39.1 EF-hand
View Download 0.254 a.159.1 Protein serine/threonine phosphatase 2C, C-terminal domain
View Download 0.253 a.105.1 FIS-like
View Download 0.250 d.43.1 Elongation factor Ts (EF-Ts), dimerisation domain
View Download 0.246 d.57.1 DNA damage-inducible protein DinI
View Download 0.238 a.4.1 Homeodomain-like
View Download 0.235 f.28.1 Nonheme 11 kDa protein of cytochrome bc1 complex (Ubiquinol-cytochrome c reductase)
View Download 0.228 a.4.9 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3
View Download 0.226 a.42.1 MDM2
View Download 0.225 a.46.2 Nucleoside phosphorylase/phosphoribosyltransferase N-terminal domain
View Download 0.220 a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.218 a.23.1 HSC20 (HSCB), C-terminal oligomerisation domain
View Download 0.217 a.164.1 C-terminal domain of DFF45/ICAD (DFF-C domain)
View Download 0.217 a.74.1 Cyclin-like
View Download 0.213 d.235.1 Hypothetical protein Yhr087W
View Download 0.213 a.181.1 Antibiotic binding domain of TipA-like multidrug resistance regulators
View Download 0.206 a.4.5 "Winged helix" DNA-binding domain
View Download 0.204 a.46.1 Methionine synthase domain
View Download 0.201 c.58.1 Aminoacid dehydrogenase-like, N-terminal domain

Predicted Domain #2
Region A:
Residues: [76-257]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DTPRWTYFSY ALGVFLYQTF DGCDGVHARR INQSGPLGEL FDHSIDAINS TLSIFIFASE  60
   61 TGMGFSYNLM LSQFAMLTNF YLSTWEEYHT HTLYLSEFSG PVEGILIVCV SLILTGIYGK 120
  121 QVIWHTYLFT ITVGDKVIDV DTLDIVFSLA VFGLVMNALS AKRNVDKYYR NSTSSANNIT 180
  181 QI

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 11.920819
Match: PF01066
Description: CDP-alcohol phosphatidyltransferase

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [258-391]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EQDSAIKGLL PFFAYYASIA LLVWMQPSFI TLSFILSVGF TGAFTVGRII VCHLTKQSFP  60
   61 MFNAPMLIPL CQIVLYKICL SLWGIESNKI VFALSWLGFG LSLGVHIMFM NDIIHEFTEY 120
  121 LDVYALSIKR SKLT

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.960 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.945 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.941 N/A N/A f.36.1 Neurotransmitter-gated ion-channel pransmembrane pore
View Download 0.913 N/A N/A a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.892 N/A N/A a.74.1 Cyclin-like


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle