YRC Public Data Repository - Protein Structure Prediction

Protein:	YHR122W
Organism:	Saccharomyces cerevisiae
Length:	231 amino acids
Reference:	Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YHR122W.

Description	E-value	Query Range	Subject Range
YHS2_YEAST - MIP18 family protein YHR122W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHR122W PE=... gi\|190405901 - gi\|190405901\|gb\|EDV09168.1\| protein FAM96B [Saccharomyces cerevisiae RM11-1a] gi\|207344587 - gi\|207344587\|gb\|EDZ71686.1\| YHR122Wp-like protein [Saccharomyces cerevisiae AWRI1631] YHR122W - Protein of unknown function required for establishment of sister chromatid cohesion; synthetically l...	2.0E-92	[1..231]	[1..231]
gi\|220958760, gi... - gi\|220958760\|gb\|ACL91923.1\| CG7949-PA [synthetic construct], gi\|220952360\|gb\|ACL88723.1\| CG7949-PA [... CG7949-PA - This gene is referred to in FlyBase by the symbol Dmel\CG7949 (CG7949, FBgn0036107). It is a protein...	2.0E-61	[71..228]	[1..153]
FAM96B - family with sequence similarity 96, member B	1.0E-59	[75..227]	[12..159]
MIP18_MOUSE - Mitotic spindle-associated MMXD complex subunit MIP18 OS=Mus musculus GN=Fam96b PE=1 SV=1	3.0E-59	[75..227]	[12..159]
YIVG_SCHPO - MIP18 family protein C144.16 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPAC144.16 PE... SPAC144.16 - DUF59 family protein	2.0E-58	[6..230]	[7..178]
CE16053 - status:Confirmed UniProt:O62252 protein_id:CAB07619.1	2.0E-55	[75..229]	[6..158]
U195_ARATH, U195... - (Q9C9G6) Hypothetical UPF0195 protein At1g68310, UPF0195 protein At1g68310 OS=Arabidopsis thaliana G...	2.0E-49	[71..227]	[1..155]
gi\|19069380, gi\|... - gi\|19074738\|ref\|NP_586244.1\| similarity to HYPOTHETICAL PROTEIN YHS2_YEAST [Encephalitozoon cuniculi... gi\|19074738 - gi\|19074738\|ref\|NP_586244.1\| similarity to HYPOTHETICAL PROTEIN YHS2_YEAST [Encephalitozoon cuniculi...	2.0E-46	[104..227]	[27..156]

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Predicted Domain #1

Region A:
Residues: [1-100]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEFLNENPD ILEENQLPTR KEDSTKDLLL GGFSNEATLE RRSLLLKIDH SLKSQVLQDI  60
   61 EVLDKLLSIR IPPELTSDED SLPAESEDES VAGGGKEEEE

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [101-231]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDLIDAQEIY DLIAHISDPE HPLSLGQLSV VNLEDIDVHD SGNQNEMAEV VIKITPTITH  60
   61 CSLATLIGLG IRVRLERSLP PRFRITILLK KGTHDSENQV NKQLNDKERV AAACENEQLL 120
  121 GVVSKMLVTC K

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	10.080922
Match:	PF01883
Description:	Domain of unknown function DUF59

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	1.7754423394137	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: